Synthesis and biological evaluation of novel flavonols as potential anti-prostate cancer agents

European Journal of Medicinal Chemistry

Volumn 54, Issue , 2012, Pages 952-958

  Britton, Robert G ^a   Horner Glister, Emma ^a   Pomenya, Odette A ^a   Smith, Ewan E ^a   Denton, Roanne ^a   Jenkins, Paul R ^a   Steward, William P ^a   Brown, Karen ^a   Gescher, Andreas ^a   Sale, Stewart ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

AR signalling pathway; Flavonols; Prostate cancer management

Indexed keywords

3' METHOXYFLAVONOL; 3',4' DIMETHOXYFLAVONOL; 3',4',5' TRIHYDROXYFLAVONOL; 3',4',5' TRIMETHOXYFLAVONOL; 3',5' DIMETHOXYFLAVONOL; 3,3',4',5' TETRAMETHOXYFLAVONE; 4' METHOXYFLAVONOL; 5,7 DIFLUORO 3',4' DIHYDROXYFLAVONOL; 5,7 DIFLUORO 3',4' DIMETHOXYFLAVONOL; 5,7 DIFLUORO 3',4',5' TRIMETHOXYFLAVONOL; 5,7 DIFLUORO 4' HYDROXYFLAVONOL; 5,7 DIFLUORO 4' METHOXYFLAVONOL; 6 FLUORO 3',4',5' TRIMETHOXYFLAVONOL; 7 FLUORO 3',4' DIHYDROXYFLAVONOL; 7 FLUORO 3',4' DIMETHOXYFLAVONOL; 7 FLUORO 3',4',5' TRIHYDROXYFLAVONOL; 7 FLUORO 3',4',5' TRIMETHOXYFLAVONOL; 7 FLUORO 4' HYDROXYFLAVONOL; 7 FLUORO 4' METHOXYFLAVONOL; ANTINEOPLASTIC AGENT; FISETIN; FLAVONE DERIVATIVE; FLAVONOL; FLAVONOL DERIVATIVE; HYDROXYL GROUP; KAEMPFEROL; MYRICETIN; QUERCETIN; ROBINETIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; GROWTH INHIBITION; HUMAN; HUMAN CELL; IC 50; PROSTATE CANCER;

ANTINEOPLASTIC AGENTS; BIOLOGICAL AVAILABILITY; CELL LINE, TUMOR; CHEMISTRY TECHNIQUES, SYNTHETIC; DRUG STABILITY; FLAVONOLS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MALE; PROSTATIC NEOPLASMS;

EID: 84864399953     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.06.031     Document Type: Article

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