Serology in adults with celiac disease: Limited accuracy in patients with mild histological lesions

Internal and Emergency Medicine

Volumn 7, Issue 4, 2012, Pages 337-342

  Licata, Anna ^a   Cappello, Maria ^a   Arini, Andrea ^a   Florena, Ada M ^a   Randazzo, Claudia ^a   Butera, Giuseppe ^a   Almasio, Piero L ^a   Craxì, Antonio ^a  

^a UNIVERSITY OF PALERMO   (Italy)

Author keywords

Celiac disease; Duodenal histology; Minimal lesions; Serology

Indexed keywords

IMMUNOGLOBULIN A;

ADOLESCENT; ADULT; AGED; ARTICLE; BLOOD; CELIAC DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENETIC MARKER; GENETICS; HUMAN; INTESTINE MUCOSA; ITALY; MALE; MIDDLE AGED; NONPARAMETRIC TEST; PATHOLOGY; PROSPECTIVE STUDY; SEVERITY OF ILLNESS INDEX;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CELIAC DISEASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENETIC MARKERS; HUMANS; IMMUNOGLOBULIN A; INTESTINAL MUCOSA; ITALY; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; STATISTICS, NONPARAMETRIC; YOUNG ADULT;

EID: 84864398650     PISSN: 18280447     EISSN: 19709366     Source Type: Journal    
DOI: 10.1007/s11739-011-0585-8     Document Type: Article

References (34)

1. Di Sabatino A, Corazza GR (2009) Coeliac disease. Lancet 373: 1480-1493.
2. Gasbarrini G, Miele L, Malandrino N, Grieco A, Addolorato G, Gasbarrini A et al (2009) Celiac disease in the 21st century: issues of under- and over-diagnosis. Int J Immunopathol Pharmacol 22: 1-7.
3. Farrell RJ, Kelly CP (2002) Celiac sprue. N Engl J Med 346: 180-188.
4. Green PH, Cellier C (2007) Celiac disease. N Engl J Med 357: 1731-1743.
5. Kagnoff MF (2005) Overview and pathogenesis of celiac disease. Gastroenterology 128: S10-S18.
6. Alaedini A, Green PH (2005) Narrative review: celiac disease-understanding a complex autoimmune disorder. Ann Intern Med 142: 289-298.
7. Dewar DH, Ciclitira PJ (2005) Clinical features and diagnosis of celiac disease. Gastroenterology 128: S19-S24.
8. Green PH, Jabri B (2006) Celiac disease. Annu Rev Med 57: 207-221.
9. Hill ID, Dirks MH, Liptak GS, Colletti RB, Fasano A, Guandalini S et al (2005) Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr 40: 1-19.
10. Rostom A, Dube C, Cranney A, Saloojee N, Sy R, Garritty C et al (2005) The diagnostic accuracy of serologic tests for celiac disease: a systematic review. Gastroenterology 128: S38-S46.
11. Donaldson MR, Firth SD, Wimpee H, Leiferman KM, Zone JJ, Horsley W, O'Gorman MA, Jackson WD, Neuhausen SL, Hull Cm, Book LS (2007) Correlation of duodenal histology with tissue transglutaminase and endomysial antibody levels in pediatric celiac disease. Clin Gastroenterol Hepatol 5: 567-573.
12. Clemente MG, Musu MP, Frau F, Brusco G, Sole G, Corazza GR et al (2000) Immune reaction against the cytoskeleton in coeliac disease. Gut 47: 520-526.
13. NIH Consensus Development Conference on Celiac Disease (2004) NIH Consens State Sci Statements. 21: 1-23.
14. Marsh MN (1992) Gluten, major histocompatibility complex, and the small intestine. A molecular and immunologic approach to the spectrum of gluten sensitivity ['celiac sprue']. Gastroenterology 102: 330-354.
15. Oberhuber G, Granditsch G, Vogelsang H (1999) The histopathology of celiac disease: time for a standardized report scheme for pathologists. Eur J Gastroenterol Hepatol 11: 1185-1194.
16. Hill ID, Bhatnagar S, Cameron DJS et al (2002) Celiac disease: working group report of the first world congress of pediatric gastroenterology, hepatology and nutrition. J Pediatr Gastroenterol Nutr 35: S78-S88.
17. Tursi A, Brandimarte G, Giorgetti GM (2003) Prevalence of anti tissue transglutaminase antibodies in different degrees of intestinal damage in celiac disease. J Clin Gastroenterol 36: 219-221.
18. Tursi A, Brandimarte G (2003) The symptomatic and histologic response to a gluten-free diet in patients with borderline enteropathy. J Clin Gastroenterol 36: 13-17.
19. Abrams JA, Diamond B, Rotterdam H, Green PH (2004) Seronegative celiac disease: increased prevalence with lesser degrees of villous atrophy. Dig Dis Sci 49: 546-550.
20. Dubé C, Rostom A, Sy R, Cranney A, Saloojee N, Garritty C et al (2005) The prevalence of celiac disease in average-risk and at-risk Western European populations: a systematic review. Gastroenterology 128: S57-S67.
21. Hill ID (2005) What are the sensitivity and specificity of serologic tests for celiac disease? Do sensitivity and specificity vary in different populations? Gastroenterology 128: S25-S32.
22. Tursi A, Brandimarte G, Giorgetti G, Gigliobianco A, Lombardi D, Gasbarrini G (2001) Low prevalence of antigliadin and anti-endomysium antibodies in subclinical/silent celiac disease. Am J Gastroenterol 96: 1507-1510.
23. Rostami K, Kerckhaert J, Tiemessen R, Meijer J, Mulder C (1999) The relationship between anti-endomysium antibodies and villous atrophy in coeliac disease using both monkey and human substrate. Eur J Gastroenterol Hepatol 11: 439-442.
24. Steele R (2011) CRF. Diagnosis and management of coeliac disease in children. Postgrad Med J 87: 19-25.
25. Dickey W, Hughes DF, McMillan SA (2000) Reliance on serum endomysial antibody testing underestimates the true prevalence of coeliac disease by one fifth. Scand J Gastroenterol 35: 181-183.
26. Goldstein NS (2004) Non-gluten sensitivity-related small bowel villous flattening with increased intraepithelial lymphocytes: not all that flattens is celiac sprue. Am J Clin Pathol 121: 546-550.
27. Biagi F, Bianchi PI, Campanella J, Badulli C, Martinetti M, Klersy C et al (2008) The prevalence and the causes of minimal intestinal lesions in patients complaining of symptoms suggestive of enteropathy: a follow-up study. J Clin Pathol 61: 1116-1118.
28. Verdu EF, Armstrong D, Murray JA (2009) Between celiac disease and irritable bowel syndrome: the "no man's land" of gluten sensitivity. Am J Gastroenterol 104: 1587-1594.
29. Granito A, Muratori P, Cassani F, Pappas G, Muratori L, Agostinelli D et al (2004) Anti-actin IgA antibodies in severe coeliac disease. Clin Exp Immunol 137: 386-392.
30. Murray JA, Rubio-Tapia A, van Dyke CT et al (2008) Mucosal atrophy in celiac disease: extent of involvement, correlation with clinical presentation, and response to treatment. Clin Gastroenterol Hepatol 6: 186-193.
31. Karinen H, Karkkainen P, Pihlajamaki J et al (2006) Gene dose effect of the DQB1*0201 allele contributes to severity of coeliac disease. Scand J Gastroenterol 41: 191-199.
32. Jores RD, Frau F, Cucca F et al (2007) HLA-DQB1*0201 homozygosis predisposes to severe intestinal damage in celiac disease. Scand J Gastroenterol 42: 48-53.
33. Johnson TC, Diamond B, Memeo L et al (2004) Relationship of HLA-DQ8 and severity of celiac disease: comparison of New York and Parisian cohorts. Clin Gastroenterol Hepatol 2: 888-894.
34. Rondonotti E, Spada C, Cave D et al (2007) Video capsule enteroscopy in the diagnosis of celiac disease: a multicenter study. Am J Gastroenterol 102: 1624-1631.