Krüppel-like factor 4 contributes to high phosphate-induced phenotypic switching of vascular smooth muscle cells into osteogenic cells

Journal of Biological Chemistry

Volumn 287, Issue 31, 2012, Pages 25706-25714

  Yoshida, Tadashi ^a   Yamashita, Maho ^a   Hayashi, Matsuhiko ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM DEPOSITION; CHRONIC KIDNEY DISEASE; DIFFERENTIATION MARKERS; OSTEOGENIC; OSTEOGENIC CELLS; OSTEOPONTIN; PHENOTYPIC SWITCHING; PHOSPHATE CONCENTRATION; PROMOTER REGION; SMOOTH MUSCLES; TRANSCRIPTIONAL REPRESSORS; VASCULAR CALCIFICATION; VASCULAR SMOOTH MUSCLE CELLS;

BIOMINERALIZATION; BLOOD VESSELS; BONE; PHOSPHORYLATION; PROTEINS;

GENE EXPRESSION;

ADENINE; ALPHA SMOOTH MUSCLE ACTIN; KRUPPEL LIKE FACTOR 4; OSTEOPONTIN; PHOSPHATE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR ELK 1; TRANSCRIPTION FACTOR RUNX2; ACTIN; DIFFERENTIATION ANTIGEN; KRUPPEL LIKE FACTOR; RUNX2 PROTEIN, RAT; SMOOTH MUSCLE ACTIN, RAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CALCIFICATION; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE; GENE EXPRESSION PROFILING; GENE SWITCHING; KRUPPEL LIKE FACTOR 4 GENE; MALE; MOLECULAR DYNAMICS; NONHUMAN; OSTEOBLAST; OSTEOPONTIN GENE; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; RUNX2 GENE; SMOOTH MUSCLE 22 ALPHA GENE; SMOOTH MUSCLE ALPHA ACTIN GENE; SMOOTH MUSCLE FIBER; ANIMAL; BLOOD VESSEL CALCIFICATION; CELL CULTURE; CELL TRANSDIFFERENTIATION; CHEMICALLY INDUCED DISORDER; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN PROCESSING; RNA INTERFERENCE; SPRAGUE DAWLEY RAT; THORACIC AORTA; UREMIA; VASCULAR SMOOTH MUSCLE;

RATTUS;

ACTINS; ANIMALS; ANTIGENS, DIFFERENTIATION; AORTA, THORACIC; CELL TRANSDIFFERENTIATION; CELLS, CULTURED; CORE BINDING FACTOR ALPHA 1 SUBUNIT; ETS-DOMAIN PROTEIN ELK-1; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MALE; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; OSTEOBLASTS; PHENOTYPE; PHOSPHATES; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RATS, SPRAGUE-DAWLEY; RNA INTERFERENCE; UREMIA; VASCULAR CALCIFICATION;

EID: 84864394228     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.361360     Document Type: Article

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