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Volumn 56, Issue 8, 2012, Pages 4439-4449

Experimental central nervous system aspergillosis therapy: Efficacy, drug levels and localization, immunohistopathology, and toxicity

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B DEOXYCHOLATE; AMPHOTERICIN B LIPID COMPLEX; CASPOFUNGIN; INTERCELLULAR ADHESION MOLECULE 1; PADGEM PROTEIN; VORICONAZOLE;

EID: 84864387255     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.06015-11     Document Type: Article
Times cited : (32)

References (41)
  • 1
    • 0029565618 scopus 로고
    • Infusion-related toxicity of three different amphotericin B formulations and its relation to cytokine plasma levels
    • Arning M, Kliche KO, Heer-Sonderhoff AH, Wehmeier A. 1995. Infusion-related toxicity of three different amphotericin B formulations and its relation to cytokine plasma levels. Mycoses 38:459-465. (Pubitemid 26042075)
    • (1995) Mycoses , vol.38 , Issue.11-12 , pp. 459-465
    • Arning, M.1    Kliche, K.O.2    Heer-Sonderhoff, A.H.3    Wehmeier, A.4
  • 2
    • 0031893392 scopus 로고    scopus 로고
    • Toxicological profile and pharmacokinetics of a unilamellar liposomal vesicle formulation of amphotericin B in rats
    • Boswell GW, Bekersky I, Buell D, Hiles R, Walsh TJ. 1998. Toxicological profile and pharmacokinetics of a unilamellar liposomal vesicle formulation of amphotericin B in rats. Antimicrob. Agents Chemother. 42:263-268. (Pubitemid 28114429)
    • (1998) Antimicrobial Agents and Chemotherapy , vol.42 , Issue.2 , pp. 263-268
    • Boswell, G.W.1    Bekersky, I.2    Buell, D.3    Hiles, R.4    Walsh, T.J.5
  • 4
    • 0037311124 scopus 로고    scopus 로고
    • Efficacy of amphotericin B or itraconazole in a murine model of central nervous system Aspergillus infection
    • DOI 10.1128/AAC.47.2.813-815.2003
    • Chiller TM, Sobel RA, Luque JC, Clemons KV, Stevens DA. 2003. Efficacy of amphotericin B or itraconazole in a murine model of central nervous system Aspergillus infection. Antimicrob. Agents Chemother. 47:813-815. (Pubitemid 36158122)
    • (2003) Antimicrobial Agents and Chemotherapy , vol.47 , Issue.2 , pp. 813-815
    • Chiller, T.M.1    Sobel, R.A.2    Luque, J.C.3    Clemons, K.V.4    Stevens, D.A.5
  • 5
    • 28844507822 scopus 로고    scopus 로고
    • Comparative efficacies of conventional amphotericin B, liposomal amphotericin B (AmBisome), caspofungin, micafungin, and voriconazole alone and in combination against experimental murine central nervous system aspergillosis
    • DOI 10.1128/AAC.49.12.4867-4875.2005
    • Clemons KV, Espiritu M, Parmar R, Stevens DA. 2005. Comparative efficacies of conventional amphotericin B, liposomal amphotericin B (AmBisome), caspofungin, micafungin, and voriconazole alone and in combination against experimental murine central nervous system aspergillosis. Antimicrob. Agents Chemother. 49:4867-4875. (Pubitemid 41778896)
    • (2005) Antimicrobial Agents and Chemotherapy , vol.49 , Issue.12 , pp. 4867-4875
    • Clemons, K.V.1    Espiritu, M.2    Parmar, R.3    Stevens, D.A.4
  • 6
    • 33748035696 scopus 로고    scopus 로고
    • Efficacy of Abelcet alone, or in combination therapy, against experimental central nervous system aspergillosis
    • DOI 10.1093/jac/dkl236
    • Clemons KV, Parmar R, Martinez M, Stevens DA. 2006. Efficacy of Abelcet alone, or in combination therapy, against experimental central nervous system aspergillosis. J. Antimicrob. Chemother. 58:466-469. (Pubitemid 44294969)
    • (2006) Journal of Antimicrobial Chemotherapy , vol.58 , Issue.2 , pp. 466-469
    • Clemons, K.V.1    Parmar, R.2    Martinez, M.3    Stevens, D.A.4
  • 7
    • 80054709751 scopus 로고    scopus 로고
    • Therapeutic and toxicologic studies in a murine model of invasive pulmonary aspergillosis
    • Clemons KV, Schwartz JA, Stevens DA. 2011. Therapeutic and toxicologic studies in a murine model of invasive pulmonary aspergillosis. Med. Mycol. 49:834-847.
    • (2011) Med. Mycol. , vol.49 , pp. 834-847
    • Clemons, K.V.1    Schwartz, J.A.2    Stevens, D.A.3
  • 8
    • 0035991739 scopus 로고    scopus 로고
    • Efficacy of intravenous liposomal amphotericin B (AmBisome) against coccidioidal meningitis in rabbits
    • DOI 10.1128/AAC.46.8.2420-2426.2002
    • Clemons KV, Sobel RA, Williams PL, Pappagianis D, Stevens DA. 2002. Efficacy of intravenous liposomal amphotericin B (AmBisome) against coccidioidal meningitis in rabbits. Antimicrob. Agents Chemother. 46:2420-2426. (Pubitemid 34793444)
    • (2002) Antimicrobial Agents and Chemotherapy , vol.46 , Issue.8 , pp. 2420-2426
    • Clemons, K.V.1    Sobel, R.A.2    Williams, P.L.3    Pappagianis, D.4    Stevens, D.A.5
  • 9
    • 28444440655 scopus 로고    scopus 로고
    • Differential expression of selectins by mouse brain capillary endothelial cells in vitro in response to distinct inflammatory stimuli
    • DOI 10.1016/j.neulet.2005.09.028, PII S0304394005010803
    • Coisne C, et al. 2006. Differential expression of selectins by mouse brain capillary endothelial cells in vitro in response to distinct inflammatory stimuli. Neurosci. Lett. 392:216-220. (Pubitemid 41739628)
    • (2006) Neuroscience Letters , vol.392 , Issue.3 , pp. 216-220
    • Coisne, C.1    Faveeuw, C.2    Delplace, Y.3    Dehouck, L.4    Miller, F.5    Cecchelli, R.6    Dehouck, B.7
  • 10
    • 79956358982 scopus 로고    scopus 로고
    • Polyene macrolide antifungal drugs trigger interleukin-1β secretion by activating the NLRP3 inflammasome
    • doi:10.1371/journal.pone.0019588
    • Darisipudi MN, Allam R, Rupanagudi KV, Anders HJ. 2011. Polyene macrolide antifungal drugs trigger interleukin-1β secretion by activating the NLRP3 inflammasome. PLoS One 6:e19588. doi:10.1371/journal.pone.0019588.
    • (2011) PLoS One , vol.6
    • Darisipudi, M.N.1    Allam, R.2    Rupanagudi, K.V.3    Anders, H.J.4
  • 12
    • 0025241257 scopus 로고
    • Antifungal and surgical treatment of invasive aspergillosis: Review of 2,121 published cases
    • Denning DW, Stevens DA. 1990. Antifungal and surgical treatment of invasive aspergillosis: review of 2,121 published cases. Rev. Infect. Dis. 12:1147-1201.
    • (1990) Rev. Infect. Dis. , vol.12 , pp. 1147-1201
    • Denning, D.W.1    Stevens, D.A.2
  • 13
    • 0036295560 scopus 로고    scopus 로고
    • The adhesion molecule ICAM-1 and its regulation in relation with the blood-brain barrier
    • Dietrich JB. 2002. The adhesion molecule ICAM-1 and its regulation in relation with the blood-brain barrier. J. Neuroimmunol. 128:58-68.
    • (2002) J. Neuroimmunol. , vol.128 , pp. 58-68
    • Dietrich, J.B.1
  • 14
    • 60849135712 scopus 로고    scopus 로고
    • Cerebral microglia recruit monocytes into the brain in response to tumor necrosis factor-α signaling during peripheral organ inflammation
    • D'Mello C, Le T, Swain MG. 2009. Cerebral microglia recruit monocytes into the brain in response to tumor necrosis factor-α signaling during peripheral organ inflammation. J. Neurosci. 29:2089-2102.
    • (2009) J. Neurosci. , vol.29 , pp. 2089-2102
    • D'Mello, C.1    Le, T.2    Swain, M.G.3
  • 16
    • 67249101874 scopus 로고    scopus 로고
    • Pharmacokinetics and biodistribution of amphotericin B in rats following oral administration in a novel lipid-based formulation
    • Gershkovich P, et al. 2009. Pharmacokinetics and biodistribution of amphotericin B in rats following oral administration in a novel lipid-based formulation. J. Antimicrob. Chemother. 64:101-108.
    • (2009) J. Antimicrob. Chemother. , vol.64 , pp. 101-108
    • Gershkovich, P.1
  • 19
    • 0026592418 scopus 로고
    • Comparison of antifungal activity of amphotericin B deoxycholate suspension with that of amphotericin B cholesteryl sulfate colloidal dispersion
    • Hanson LH, Stevens DA. 1992. Comparison of antifungal activity of amphotericin B deoxycholate suspension with that of amphotericin B cholesteryl sulfate colloidal dispersion. Antimicrob. Agents Chemother. 36:486-488.
    • (1992) Antimicrob. Agents Chemother. , vol.36 , pp. 486-488
    • Hanson, L.H.1    Stevens, D.A.2
  • 20
    • 41649120398 scopus 로고    scopus 로고
    • Injury of the blood brain barrier and up-regulation of ICAM-1 in polymicrobial sepsis
    • Hofer S, et al. 2008. Injury of the blood brain barrier and up-regulation of ICAM-1 in polymicrobial sepsis. J. Surg. Res. 146:276-281.
    • (2008) J. Surg. Res. , vol.146 , pp. 276-281
    • Hofer, S.1
  • 21
    • 24044479088 scopus 로고    scopus 로고
    • Efficacy of Abelcet and caspofungin, alone or in combination, against CNS aspergillosis in a murine model
    • DOI 10.1093/jac/dki178
    • Imai J, Singh G, Fernandez B, Clemons KV, Stevens DA. 2005. Efficacy of Abelcet and caspofungin, alone or in combination, against CNS aspergillosis in a murine model. J. Antimicrob. Chemother. 56:166-171. (Pubitemid 41418352)
    • (2005) Journal of Antimicrobial Chemotherapy , vol.56 , Issue.1 , pp. 166-171
    • Imai, J.1    Singh, G.2    Fernandez, B.3    Clemons, K.V.4    Stevens, D.A.5
  • 22
    • 4644342873 scopus 로고    scopus 로고
    • Efficacy of posaconazole in a murine model of central nervous system aspergillosis
    • DOI 10.1128/AAC.48.10.4063-4066.2004
    • Imai JK, Singh G, Clemons KV, Stevens DA. 2004. Efficacy of posaconazole in a murine model of central nervous system aspergillosis. Antimicrob. Agents Chemother. 48:4063-4066. (Pubitemid 39304651)
    • (2004) Antimicrobial Agents and Chemotherapy , vol.48 , Issue.10 , pp. 4063-4066
    • Imai, J.K.1    Singh, G.2    Clemons, K.V.3    Stevens, D.A.4
  • 23
    • 0032860357 scopus 로고    scopus 로고
    • Worst-rank score analysis with informatively missing observations in clinical trials
    • DOI 10.1016/S0197-2456(99)00022-7, PII S0197245699000227
    • Lachin JM. 1999. Worst-rank score analysis with informatively missing observations in clinical trials. Control. Clin. Trials 20:408-422. (Pubitemid 29460918)
    • (1999) Controlled Clinical Trials , vol.20 , Issue.5 , pp. 408-422
    • Lachin, J.M.1
  • 24
    • 0029744880 scopus 로고    scopus 로고
    • Liposomal amphotericin B (AmBisome) reduces dissemination of infection as compared with amphotericin B deoxycholate (Fungizone) in a rat model of pulmonary aspergillosis
    • Leenders AC, de Marie S, ten Kate MT, Bakker-Woudenberg IA, Verbrugh HA. 1996. Liposomal amphotericin B (AmBisome) reduces dissemination of infection compared with amphotericin B deoxycholate (Fungizone) in a rat model of pulmonary aspergillosis. J. Antimicrob. Chemother. 38:215-225. (Pubitemid 26302582)
    • (1996) Journal of Antimicrobial Chemotherapy , vol.38 , Issue.2 , pp. 215-225
    • Leenders, A.C.A.P.1    De Marie, S.2    Ten, K.M.T.3    Bakker-Woudenberg, I.A.J.M.4    Verbrugh, H.A.5
  • 25
    • 77955358447 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of amphotericin B deoxycholate, liposomal amphotericin B, and amphotericin B lipid complex in an in vitro model of invasive pulmonary aspergillosis
    • Lestner JM, et al. 2010. Pharmacokinetics and pharmacodynamics of amphotericin B deoxycholate, liposomal amphotericin B, and amphotericin B lipid complex in an in vitro model of invasive pulmonary aspergillosis. Antimicrob. Agents Chemother. 54:3432-3441.
    • (2010) Antimicrob. Agents Chemother. , vol.54 , pp. 3432-3441
    • Lestner, J.M.1
  • 26
    • 0028605251 scopus 로고
    • Comparative capacity of four antifungal agents to stimulate murine macrophages to produce tumour necrosis factor alpha: An effect that is attenuated by pentoxifylline, liposomal vesicles, and dexamethasone
    • Louie A, Baltch AL, Franke MA, Smith RP, Gordon MA. 1994. Comparative capacity of four antifungal agents to stimulate murine macrophages to produce tumour necrosis factor alpha: an effect that is attenuated by pentoxifylline, liposomal vesicles, and dexamethasone. J. Antimicrob. Chemother. 34:975-987.
    • (1994) J. Antimicrob. Chemother. , vol.34 , pp. 975-987
    • Louie, A.1    Baltch, A.L.2    Franke, M.A.3    Smith, R.P.4    Gordon, M.A.5
  • 27
    • 33644839612 scopus 로고    scopus 로고
    • Signaling mechanisms regulating endothelial permeability
    • Mehta D, Malik AB. 2006. Signaling mechanisms regulating endothelial permeability. Physiol. Rev. 86:279-367.
    • (2006) Physiol. Rev. , vol.86 , pp. 279-367
    • Mehta, D.1    Malik, A.B.2
  • 28
    • 55649108603 scopus 로고    scopus 로고
    • Treatment of invasive fungal infections in immunocompromised and transplant patients: AmBiLoad trial and other new data
    • Munoz P, Guinea J, Narbona MT, Bouza E. 2008. Treatment of invasive fungal infections in immunocompromised and transplant patients: AmBiLoad trial and other new data. Int. J. Antimicrob. Agents 32(Suppl 2):S125-S131.
    • (2008) Int. J. Antimicrob. Agents , vol.32 , Issue.SUPPL. 2
    • Munoz, P.1    Guinea, J.2    Narbona, M.T.3    Bouza, E.4
  • 29
    • 0033788307 scopus 로고    scopus 로고
    • Mononuclear cell recruitment, granuloma assembly, and response to treatment in experimental visceral leishmaniasis: Intracellular adhesion molecule 1-dependent and -independent regulation
    • Murray HW. 2000. Mononuclear cell recruitment, granuloma assembly, and response to treatment in experimental visceral leishmaniasis: intracellular adhesion molecule 1-dependent and -independent regulation. Infect. Immun. 68:6294-6299.
    • (2000) Infect. Immun. , vol.68 , pp. 6294-6299
    • Murray, H.W.1
  • 30
    • 77956109969 scopus 로고    scopus 로고
    • Liposomal amphotericin B and echinocandins as monotherapy or sequential or concomitant therapy in murine disseminated and pulmonary Aspergillus fumigatus infections
    • Olson JA, et al. 2010. Liposomal amphotericin B and echinocandins as monotherapy or sequential or concomitant therapy in murine disseminated and pulmonary Aspergillus fumigatus infections. Antimicrob. Agents Chemother. 54:3884-3894.
    • (2010) Antimicrob. Agents Chemother. , vol.54 , pp. 3884-3894
    • Olson, J.A.1
  • 31
    • 75749133624 scopus 로고    scopus 로고
    • Immune cell entry to central nervous system - Current understanding and prospective therapeutic targets
    • Prendergast CT, Anderton SM. 2009. Immune cell entry to central nervous system - current understanding and prospective therapeutic targets. Endocr. Metab. Immune Disord. Drug Targets 9:315-327.
    • (2009) Endocr. Metab. Immune Disord. Drug Targets , vol.9 , pp. 315-327
    • Prendergast, C.T.1    Anderton, S.M.2
  • 32
    • 12244261220 scopus 로고    scopus 로고
    • Differential expression of genes encoding immunomodulatory proteins in response to amphotericin B in human mononuclear cells identified by cDNA microarray analysis
    • DOI 10.1093/jac/dkf234
    • Rogers PD, Pearson MM, Cleary JD, Sullivan DC, Chapman SW. 2002. Differential expression of genes encoding immunomodulatory proteins in response to amphotericin B in human mononuclear cells identified by cDNA microarray analysis. J. Antimicrob. Chemother. 50:811-817. (Pubitemid 36032799)
    • (2002) Journal of Antimicrobial Chemotherapy , vol.50 , Issue.6 , pp. 811-817
    • Rogers, P.D.1    Pearson, M.M.2    Cleary, J.D.3    Sullivan, D.C.4    Chapman, S.W.5
  • 33
    • 0033805643 scopus 로고    scopus 로고
    • Amphotericin B induces expression of genes encoding chemokines and cell adhesion molecules in the human monocytic cell line THP-1
    • Rogers PD, Stiles JK, Chapman SW, Cleary JD. 2000. Amphotericin B induces expression of genes encoding chemokines and cell adhesion molecules in the human monocytic cell line THP-1. J. Infect. Dis. 182:1280-1283.
    • (2000) J. Infect. Dis. , vol.182 , pp. 1280-1283
    • Rogers, P.D.1    Stiles, J.K.2    Chapman, S.W.3    Cleary, J.D.4
  • 34
    • 0242466086 scopus 로고    scopus 로고
    • Problems in dealing with missing data and informative censoring in clinical trials
    • Shih W. 2002. Problems in dealing with missing data and informative censoring in clinical trials. Curr. Control Trials Cardiovasc. Med. 3:4.
    • (2002) Curr. Control Trials Cardiovasc. Med. , vol.3 , pp. 4
    • Shih, W.1
  • 36
    • 16244373678 scopus 로고    scopus 로고
    • Efficacy of caspofungin against central nervous system Aspergillus fumigatus infection in mice determined by TaqMan PCR and CFU methods
    • DOI 10.1128/AAC.49.4.1369-1376.2005
    • Singh G, Imai J, Clemons KV, Stevens DA. 2005. Efficacy of caspofungin against central nervous system Aspergillus fumigatus infection in mice determined by TaqMan PCR and CFU methods. Antimicrob. Agents Chemother. 49:1369-1376. (Pubitemid 40463364)
    • (2005) Antimicrobial Agents and Chemotherapy , vol.49 , Issue.4 , pp. 1369-1376
    • Singh, G.1    Imai, J.2    Clemons, K.V.3    Stevens, D.A.4
  • 38
    • 70349237082 scopus 로고    scopus 로고
    • Amphotericin B-induced nephrotoxicity: Characterization of blood and urinary biochemistry and renal morphology in mice
    • Tonomura Y, et al. 2009. Amphotericin B-induced nephrotoxicity: characterization of blood and urinary biochemistry and renal morphology in mice. Hum. Exp. Toxicol. 28:293-300.
    • (2009) Hum. Exp. Toxicol. , vol.28 , pp. 293-300
    • Tonomura, Y.1


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