The structure of an archaeal viral integrase reveals an evolutionarily conserved catalytic core yet supports a mechanism of DNA cleavage in trans

Journal of Virology

Volumn 86, Issue 15, 2012, Pages 8309-8313

  Eilers, Brian J ^a   Young, Mark J ^a   Lawrence, C Martin ^a  

^a MONTANA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRASE;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARCHAEAL VIRUS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; DISULFIDE BOND; DNA CLEAVAGE; ENZYME ACTIVE SITE; ENZYME SUBUNIT; GENETIC CONSERVATION; MOLECULAR EVOLUTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN MOTIF; SEQUENCE ANALYSIS; STRUCTURAL HOMOLOGY; STRUCTURE ACTIVITY RELATION;

ARCHAEAL VIRUSES; DNA NUCLEOTIDYLTRANSFERASES; DNA, CRUCIFORM; DNA, VIRAL; ENZYME STABILITY; EVOLUTION, MOLECULAR; INTEGRASES; PROTEIN STRUCTURE, TERTIARY; VIRAL PROTEINS;

ARCHAEA; BACTERIA (MICROORGANISMS); EUKARYOTA;

EID: 84864386293     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00547-12     Document Type: Article

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