Antioxidant, analgesic, cytotoxic and antidiarrheal activities of ethanolic Zizyphus mauritiana bark extract

Oriental Pharmacy and Experimental Medicine

Volumn 12, Issue 1, 2012, Pages 67-73

  Rahman, Shafiur ^a,b  

^a KHULNA UNIVERSITY   (Bangladesh)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Analgesic activity; Antidiarrheal activity; Antioxidant activity; Cytotoxic activity; Medicinal plant; Zizyphus mauritiana

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ACETIC ACID; ALCOHOL; ALKALOID; ANALGESIC AGENT; ANTIDIARRHEAL AGENT; ANTIOXIDANT; ASCORBIC ACID; CASTOR OIL; CYTOTOXIC AGENT; DICLOFENAC; FLAVONOID; FREE RADICAL; LOPERAMIDE; PLANT EXTRACT; PLANT GUM; STEROID; SUGAR; TANNIN DERIVATIVE; UNCLASSIFIED DRUG; ZIZYPHUS MAURITIANA EXTRACT;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIARRHEAL ACTIVITY; ANTIOXIDANT ACTIVITY; ARTEMIA; ARTICLE; BARK; CONTROLLED STUDY; CYTOTOXICITY; DIARRHEA; FEMALE; LETHALITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; WRITHING TEST;

EID: 84864377801     PISSN: 15982386     EISSN: 22111069     Source Type: Journal    
DOI: 10.1007/s13596-011-0042-2     Document Type: Article

References (58)

1. Adzu B, Amos S, Wambebe C, Gamaniel K (2001) Antinociceptive activity of Ziziphus spinachristi root bark extract. Fitoterapia 72: 334-350.
2. Ahmed M, Shikha HA, Sadhu SK, Rahman MT, Datta BK (2001) Analgesic, diuretic, and anti-inflammatory principle from Scoparia dulcis. Pharmazie 56(8): 657-660.
3. Altman DF (2001) Drugs used in gastrointestinal diseases. In: Katzung BG (ed) Basic and clinical pharmacology, 8th edn. McGraw Hill, San Francisco, pp 1070-1071.
4. Arnous A, Makris DP, Kefalas P (2001) Effect of principal polyphenolic components in relation to antioxidant characteristics of aged red wines. J Agric Food Chem 49: 5736-742.
5. Aruoma OI (2003) Methodological considerations for characterizing potential antioxidant actions of bioactive components in food plants. Mutat Res 523-524: 9-20.
6. Atta AH, Mouneir SM (2004) Antidiarrheal activity of some Egyptian medicinal plant extracts. J Ethnopharmacol 92: 303-09.
7. Bannerman PGC, Mirsky R, Jessen KR, Timpl R, Duance VC (1986) Light microscopic immunolocalization of laminin, type IV collagen, nidogen, heparan sulphate proteoglycan and fibronectin in the enteric nervous system of rat and guinea pig. J Neurocytol 15: 432-443.
8. Bhatia A, Mishra T (2010) Hypoglycemic activity of Ziziphus mauritiana aqueous ethanol seed extract in alloxan-induced diabetic mice. Pharm Biol 48(6): 604-610.
9. Bhuiyan MAR, Hoque MZ (2010) Free radical scavenging activities of Zizyphus mauritiana. Elec J Envir Agricul Food Chem 9(1): 199-206.
10. Birs W, Heller W, Micheal C, Satan M (1991) Flavonoids as antioxidant. Determination of antiradical efficiencies. Methods litcymal 186: 343-353.
11. Calixto JB, Beirith A, Ferreira J, Santos AR, Cechinel filho V, Yunes RA (2000) Naturally occurring anti-nociceptive substances from plants. Phytother Res 14: 401-418.
12. Carlos CC, Saniel MC (1990) Etiology and epidemiology of diarrhoea. Phillips J Microbio Infect Dis 19: 51-53.
13. Chevallier A (1996) The Encyclopedia of medicinal plants, Ist ednth edn. DK Publishing Inc., New York, USA, pp 55-281.
14. Dahiru D, Obidoa O (2008) Evaluation of the antioxidant effects of Ziziphus mauritiana lam. Leaf extracts against chronic ethanolinduced hepatotoxicity in rat liver. Afr J Trad CAM 5(1): 39-45.
15. Dahiru D, William ET, Nadro MS (2005) Protective effect of Ziziphus mauritiana leaf extract on carbon tetrachloride-induced liver injury. Afr J Biotechnol 4(10): 1177-179.
16. Dahiru D, Sini JM, John-Africa L (2006) Antidiarrhoeal activity of Ziziphus mauritiana root extract in rodents. Afr J Biotechnol 5(10): 941-945.
17. Das AK, Mandal SC, Banerjee SK, Sinha S, Das J, Saha BP, Pal M (1999) Studies of antidiarrheal activity of Punica granatum seed extracts. J Ethnopharmacol 68: 205-208.
18. Derardt R, Jougney S, Delevalcee F, Falhout M (1980) Release of prostaglandins E and F in an algogenic reaction and its inhibition. Eur J Pharmacol 51: 17-24.
19. Devi S, Pandey VB, Singh JP, Shah AH (1987) Peptide alkaloids from Zizyphus species. Phytochem 26(1): 3374-3375.
20. Evans WC (1989) Trease and Evan's textbook of pharmacognosy, 13th edn. Cambridge University Press, London.
21. Farnsworth NR, Soejarto DD (1991) Global importance of medicinal plants. In: Akerele O, Heywood V, Synge H (eds) The conservation of medicinal plants. Cambridge University Press, Cambridge, pp 25-51.
22. Fernanda LB, Victor AK, Amelia TH, Elisabetsky E (2002) Analgesic properties of umbellatine from psychotria umbellate. Pharm Biol 44: 54-56.
23. Franzotti EM, Santos CVF, Rodrigues HMSL, Mourao RHV, Andrade MR, Antoniolli AR (2002) Anti-inflammatory, analgesic and acute toxicity of Sida cardiafolia L. J Ethnopharmacol 72: 273-278.
24. Gaginella TS, Phillips SF (1975) Ricinoleic acid: current view of ancient oil. Digest Dis Sci 23: 1171-1177.
25. Gani A (2003) Medicinal plants of Bangladesh. Chemical Constituents and Uses. Dhaka, Asiatic Society of Bangladesh, p 434.
26. th Edition), Macmillan Publishers, New York. pp. 924-926.
27. Gulcin I, Buyukokuroglu ME, Oktay M, Kufrevioglu OI (2002) On the in vitro antioxidant properties of melatonin. J Pineal Res 33: 167-171.
28. Gupta M, Mazumdar UK, Sivahkumar T, Vamis MLM, Karki S, Sambathkumar R, Manikandan L (2003) Antioxidant and anti-inflammatory activities of Acalypha fruticosa. Nig J Nat Prod Med 07: 25-29.
29. Gupta M, Mazumder UK, Vamsi MLM, Sivakumar T, Kandar CC (2004) Anti steroidogenic activity of the two Indian medicinal plants in mice. J Ethnopharmacol 90(1): 21-25.
30. Jadhav HR, Bhutani KK (2002) Antioxidant properties of Indian medicinal plant. Phytother Res 16: 771-773.
31. Jarald EE, Joshi SB, Jain DC (2009) Antidiabetic activity of extracts and fraction of zizyphus mauritiana. Pharm Biol 47(4): 328-334.
32. Kaaria I (1998) Seed production, dispersal and germination in Cryptostegia grandifolia and Ziziphus mauritiana, two invasive shrubs in tropical woodlands of Northern Australia. Aus J Ecol 21: 324-331.
33. Kong JM, Goh NK, Chia LS, Chia TF (2003) Recent advances in traditional plant drugs and orchids. Acta Pharmacol Sin 24: 7-21.
34. Lee MF, Chen YH, Lan JL, Tseng CY, Wu CH (2004) Allergenic components of Indian jujube (Zizyphus mauritiana) show IgE cross-reactivity with latex allergen. Int Arch Aller Immunol 133(3): 211-16.
35. Lork D (1983) A new approach to acute toxicity testing. Archives Toxicol 54: 275-287.
36. Lu F, Foo LY (1995) Toxicological aspects of food antioxidants. In: Madhavi DL, Deshpande SS, Salunkhe DK (eds) Food antioxidants. Marcel Dekker, New York.
37. McLaughlin JL, Anderson JE, Chang CJ (1988) Bioactive components of Allamanda schottii. J Nat Prod 51(2): 307-8.
38. McLauglin JL, Chang CJ, Smith DL (1993): Simple bench-top bioassays (brine shrimp and potato discs) for the discovery of plant antitumour compounds. In: Human Medicinal Agents from Plants. Kinghorn, A. D. And Balandrin, M. F. (Eds.), ACS Symposium 534, Am Chem Soc, Washington DC: 112-137.
39. Meyer BN, Ferrigni NR, Putnam JE, Jawbson LB, Nicholas DE, McLaughlin JL (1982) Brine shrimp: a convenient general bioassay for active plant constituents. Planta Med 45: 31-34.
40. Michel A (2002) Tree shrub and Liana of West African zone. Margraf Publishers GMBH, Paris, 440.
41. Nwodo OFC, Alumanah EO (1991) Studies on Abrus Precatorius seeds II: antidiarrheal activity. J Ethnopharmacol 31(3): 391-395.
42. Ojewole JAO (2004) Evaluation of antidiarrheal, anti-inflammatory and antidiabetic properties of Sclerocarya birrea (A. Rich.) Hochst. stem bark aqueous extract in mice and rats. Phytotherapy Res 18: 601-608.
43. Onasanwo SA, Elegbe RA (2006) Antinociceptive and anti-inflammatory properties of the leaf extracts of Hedranthera barteri in rats and mice. African J Biomed Res 9: 117-119.
44. Rahman MAA, Moon SS (2007) Antioxidant polyphenol glycosides from the plant Draba nemorosa. Bull Korean Chem Soc 28(5): 827-831.
45. Robaki, Glyglewski RJ (1988) Flavonoids are scavengers of supeoxide anim. Biochem Pharmacol 37: 837-841.
46. Sadhu SK, Okuyama E, Fujimoto H, Ishibashi M (2003) Separation of Leucas aspera, a medicinal plant of Bangladesh, guided by prostaglandin inhibitory and antioxidant activities. Chem Pharm Bull 51(5): 595-598.
47. Said HM (1996): Medicinal Herbal, Ist edn., Hamdard Foundation Pakistan, p. 7-268.
48. Sawadogo WR, Boly R, Lompo M, Some N (2006) Anti-inflammatory, analgesic and antipyretic activities of Dicliptera verticillata. In J Pharmacol 2: 435-438.
49. Schulz V, Hänsel R, Tyler VE (2002) Fitoterapia racional: Um Guia de Fitoterapia para as Ciências da Saúde, 4th edn. Barueri, Manole, p 386.
50. Srivastava SK, Srivastava SD (1979) Structure of zizogenin, a new sapogenin from Zizyphus mauritania. Phytochem 18(10): 1758-1759.
51. Taesotikul T, Panthong A, Kanjanapothi D, Verpoorte R, Scheffer JJC (2003) Anti-inflammatory, antipyretic and antinociceptive activities of Tabernaemontana pandacaqui Poir. J Ethnopharmacol 84: 31-35.
52. Vyklicky L (1979) Techniques for the study of pain in animals, p. 773-778. In: Bonica JJ, Liebeskin, Albe-Fessard DG (eds) Advances in pain research and therapy. Raven, New York, USA.
53. Wadekar RR, Patil KS (2008) Effect of Ziziphus mauritiana leaf extracts on phagocytosis by human neutrophils. J Pharm Res 1(1): 79-83.
54. Wagner H (1989) Search for new plant constituents with potential anti-phlogistic and anti- alergic activity. Planta Med 55: 235-241.
55. Whittle BA (1964) The use of changes in capillary permeability in mice to distinguish between narcotic and non-narcotic analgesics. British J Pharmacol Chem 22: 246-253.
56. Xu GJ (1996) The Chinese materia medica. Volume 1. Chinese Medicine and Technology, Beijing, China.
57. Yusuf M, Chowdhury JU, Wahab MA, Begum J (1994) Medicinal plants of Bangladesh. BCSIR, Dhaka, pp 17-266.
58. Zavala MA, Perez S, Perez C, Vargal R, Perez RM (1998) Antidiarrhoeal activity of Waltheria americana, Commelins cuelestris and Alternanthra repens. J Ethnopharmacol 61: 41-47.