Diagnosing and monitoring cirrhosis: Liver biopsy, hepatic venous pressure gradient and elastography

Gastroenterologia y Hepatologia

Volumn 35, Issue 7, 2012, Pages 488-495

  Abraldes, Juan G ^a,b   Araujo, Isis K ^a   Turón, Fanny ^a   Berzigotti, Annalisa ^a,b,c  

^a INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c HOSPITAL CLÍNIC   (Spain)

Author keywords

Cirrosis; Portal hypertension; Varices

Indexed keywords

ANTIVIRUS AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CHELATING AGENT; STEROID;

ARTICLE; DECOMPENSATED LIVER CIRRHOSIS; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DISEASE COURSE; ECHOGRAPHY; ELASTOGRAPHY; HEPATIC VENOUS PRESSURE GRADIENT; HUMAN; LIVER BIOPSY; LIVER CIRRHOSIS; NON INVASIVE PROCEDURE; PATIENT MONITORING; PORTAL HYPERTENSION; PRESSURE GRADIENT; PROGNOSIS; SCREENING TEST; SENSITIVITY AND SPECIFICITY; TRANSIENT ELASTOGRAPHY; TREATMENT RESPONSE; VARICOSIS; VEIN CATHETERIZATION;

BIOPSY; COMPLIANCE; ELASTICITY IMAGING TECHNIQUES; ESOPHAGEAL AND GASTRIC VARICES; ESOPHAGOSCOPY; HUMANS; HYPERTENSION, PORTAL; LIVER; LIVER CIRRHOSIS; PORTAL PRESSURE; REPRODUCIBILITY OF RESULTS; TREATMENT OUTCOME;

EID: 84864365956     PISSN: 02105705     EISSN: 15789519     Source Type: Journal    
DOI: 10.1016/j.gastrohep.2012.02.010     Document Type: Article

References (58)

1. Rockey D.C., Caldwell S.H., Goodman Z.D., Nelson R.C., Smith A.D. Liver biopsy. Hepatology 2009, 49:1017-1044.
2. Bedossa P. Liver biopsy. Gastroenterol Clin Biol 2008, 32:4-7.
3. Bedossa P., Dargere D., Paradis V. Sampling variability of liver fibrosis in chronic hepatitis C. Hepatology 2003, 38:1449-1457.
4. Bosch J., Abraldes J.G., Berzigotti A., Garcia-Pagan J.C. The clinical use of HVPG measurements in chronic liver disease. Nat Rev Gastroenterol Hepatol 2009, 6:576-582.
5. Zipprich A., Winkler M., Seufferlein T., Dollinger M.M. Comparison of balloon vs. straight catheter for the measurement of portal hypertension. Aliment Pharmacol Ther 2010, 32:1351-1356.
6. Perello A., Escorsell A., Bru C., Gilabert R., Moitinho E., Garcia-Pagan J.C., et al. Wedged hepatic venous pressure adequately reflects portal pressure in hepatitis C virus-related cirrhosis. Hepatology 1999, 30:1393-1397.
7. La Mura V., Abraldes J.G., Berzigotti A., Erice E., Flores-Arroyo A., Garcia-Pagan J.C., et al. Right atrial pressure is not adequate to calculate portal pressure gradient in cirrhosis: a clinical-hemodynamic correlation study. Hepatology 2010, 51:2108-2116.
8. Groszmann R.J., Wongcharatrawee S. The hepatic venous pressure gradient: anything worth doing should be done right. Hepatology 2004, 39:280-282.
9. Yepes-Barreto I., Rincon-Rodriguez D., de la Vega Catalina-Rodriguez, Ripoll-Noiseux C., Banares-Canizares R. Technical features of liver hemodynamics and transjugular liver biopsy. Gastroenterol Hepatol 2011, 34:116-123.
10. Groszmann R.J., Abraldes J.G. Portal hypertension: from bedside to bench. J Clin Gastroenterol 2005, 39:S215.
11. Carrion J.A., Navasa M., Buti M., Torras X., Xiol X., Vergara M., et al. Hepatic elastography, position paper of the Catalan society of gastroenterology. Gastroenterol Hepatol 2011, 34:504-510.
12. Sandrin L., Fourquet B., Hasquenoph J.M., Yon S., Fournier C., Mal F., et al. Transient elastography: a new noninvasive method for assessment of hepatic fibrosis. Ultrasound Med Biol 2003, 29:1705-1713.
13. Degos F., Perez P., Roche B., Mahmoudi A., Asselineau J., Voitot H., et al. Diagnostic accuracy of FibroScan and comparison to liver fibrosis biomarkers in chronic viral hepatitis: a multicenter prospective study (the FIBROSTIC study). J Hepatol 2010, 53:1013-1021.
14. Berzigotti A., Abraldes J.G., Tandon P., Erice E., Gilabert R., Garcia-Pagan J.C., et al. Ultrasonographic evaluation of liver surface and transient elastography in clinically doubtful cirrhosis. J Hepatol 2010, 52:846-853.
15. Castera L., Foucher J., Bernard P.H., Carvalho F., Allaix D., Merrouche W., et al. Pitfalls of liver stiffness measurement: a 5-year prospective study of 13,369 examinations. Hepatology 2010, 51:828-835.
16. Berzigotti A., Rossi V., Tiani C., Pierpaoli L., Zappoli P., Riili A., et al. Prognostic value of a single HVPG measurement and Doppler-ultrasound evaluation in patients with cirrhosis and portal hypertension. J Gastroenterol 2011, 46:687-695.
17. Ziol M., Handra-Luca A., Kettaneh A., Christidis C., Mal F., Kazemi F., et al. Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with chronic hepatitis C. Hepatology 2005, 41:48-54.
18. Ganne-Carrie N., Ziol M., Douvin C., Marcellin P., Castera L., et al. Accuracy of liver stiffness measurement for the diagnosis of cirrhosis in patients with chronic liver diseases. Hepatology 2006, 44:1511-1517.
19. Wong V.W., Vergniol J., Wong G.L., Foucher J., Chan H.L., Le B.B., et al. Diagnosis of fibrosis and cirrhosis using liver stiffness measurement in nonalcoholic fatty liver disease. Hepatology 2010, 51:454-462.
20. Marcellin P., Ziol M., Bedossa P., Douvin C., Poupon R., et al. Non-invasive assessment of liver fibrosis by stiffness measurement in patients with chronic hepatitis B. Liver Int 2009, 29:242-247.
21. Gonzalez Guilabert M.I., Hinojosa Mena-Bernal C., del Pozo G.J., del Pozo Perez M.A. Retrospective study of FibroScan, APRI, FIB-4 and FORNS indexes compared with liver biopsy in the evaluation of liver fibrosis in patients with chronic hepatitis C monoinfection and HIV coinfection. Gastroenterol Hepatol 2010, 33:425-432.
22. Castera L., Le B.B., Roudot-Thoraval F., Bernard P.H., Foucher J., Merrouche W., et al. Early detection in routine clinical practice of cirrhosis and oesophageal varices in chronic hepatitis C: comparison of transient elastography (FibroScan) with standard laboratory tests and non-invasive scores. J Hepatol 2009, 50:59-68.
23. Friedrich-Rust M., Ong M.F., Martens S., Sarrazin C., Bojunga J., Zeuzem S., et al. Performance of transient elastography for the staging of liver fibrosis: a meta-analysis. Gastroenterology 2008, 134:960-974.
24. Deeks J.J., Altman D.G. Diagnostic tests 4: likelihood ratios. BMJ 2004, 329:168-169.
25. Simel D.L., Samsa G.P., Matchar D.B. Likelihood ratios for continuous test results - making the clinicians' job easier or harder?. J Clin Epidemiol 1993, 46:85-93.
26. Arena U., Vizzutti F., Abraldes J.G., Corti G., Stasi C., Moscarella S., et al. Reliability of transient elastography for the diagnosis of advanced fibrosis in chronic hepatitis C. Gut 2008, 57:1288-1293.
27. Bosch J., Garcia-Pagan J.C., Berzigotti A., Abraldes J.G. Measurement of portal pressure and its role in the management of chronic liver disease. Semin Liver Dis 2006, 26:348-362.
28. Gines P., Quintero E., Arroyo V., Teres J., Bruguera M., Rimola A., et al. Compensated cirrhosis: natural history and prognostic factors. Hepatology 1987, 7:122-128.
29. Garcia-Tsao G., Groszmann R.J., Fisher R.L., Conn H.O., Atterbury C.E., Glickman M. Portal pressure, presence of gastroesophageal varices and variceal bleeding. Hepatology 1985, 5:419-424.
30. Groszmann R.J., Garcia-Tsao G., Bosch J., Grace N.D., Burroughs A.K., Planas R., et al. Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis. N Engl J Med 2005, 353:2254-2261.
31. Ripoll C., Groszmann R., Garcia-Tsao G., Grace N., Burroughs A., Planas R., et al. Hepatic venous pressure gradient predicts clinical decompensation in patients with compensated cirrhosis. Gastroenterology 2007, 133:481-488.
32. Ripoll C., Groszmann R.J., Garcia-Tsao G., Bosch J., Grace N., Burroughs A., et al. Hepatic venous pressure gradient predicts development of hepatocellular carcinoma independently of severity of cirrhosis. J Hepatol 2009, 50:923-928.
33. Masuzaki R., Tateishi R., Yoshida H., Goto E., Sato T., Ohki T., et al. Prospective risk assessment for hepatocellular carcinoma development in patients with chronic hepatitis C by transient elastography. Hepatology 2009, 49:1954-1961.
34. Jung K.S., Kim S.U., Ahn S.H., Park Y.N., Kim Y, Park J.Y., et al. Risk assessment of hepatitis B virus-related hepatocellular carcinoma development using liver stiffness measurement (FibroScan). Hepatology 2011, 53:885-894.
35. Robic M.A., Procopet B., Metivier S., Peron J.M., Selves J., Vinel J.P., et al. Liver stiffness accurately predicts portal hypertension related complications in patients with chronic liver disease: a prospective study. J Hepatol 2011, 55:1017-1024.
36. Nagula S., Jain D., Groszmann R.J., Garcia-Tsao G. Histological-hemodynamic correlation in cirrhosis-a histological classification of the severity of cirrhosis. J Hepatol 2006, 44:111-117.
37. Carrion J.A., Navasa M., Bosch J., Bruguera M., Gilabert R., Forns X. Transient elastography for diagnosis of advanced fibrosis and portal hypertension in patients with hepatitis C recurrence after liver transplantation. Liver Transpl 2006, 12:1791-1798.
38. Bureau C., Metivier S., Peron J.M., Selves J., Robic M.A., Gourraud P.A., et al. Transient elastography accurately predicts presence of significant portal hypertension in patients with chronic liver disease. Aliment Pharmacol Ther 2008, 27:1261-1268.
39. Lemoine M., Katsahian S., Ziol M., Nahon P., Ganne-Carrie N., Kazemi F., et al. Liver stiffness measurement as a predictive tool of clinically significant portal hypertension in patients with compensated hepatitis C virus or alcohol-related cirrhosis. Aliment Pharmacol Ther 2008, 28:1102-1110.
40. Llop E., Berzigotti A., Reig M., Erice E., Reverter E., Seijo S., et al. Assessment of portal hypertension by transient elastography in patients with compensated cirrhosis and potentially resectable liver tumors. J Hepatol 2012, 56:103-108.
41. Vizzutti F., Arena U., Romanelli R.G., Rega L., Foschi M., Colagrande S., et al. Liver stiffness measurement predicts severe portal hypertension in patients with HCV-related cirrhosis. Hepatology 2007, 45:1290-1297.
42. Sanchez-Conde M., Miralles P., Bellon J.M., Rincon D., Ramirez M., Gutierrez I., et al. Use of transient elastography (FibroScan(R)) for the noninvasive assessment of portal hypertension in HIV/HCV-coinfected patients. J Viral Hepat 2011, 18:685-691.
43. Rizzo L., Calvaruso V., Cacopardo B., Alessi N., Attanasio M., Petta S., et al. Comparison of transient elastography and acoustic radiation force impulse for non-invasive staging of liver fibrosis in patients with chronic hepatitis C. Am J Gastroenterol 2011, 106:2112-2120.
44. Hirooka M., Ochi H., Koizumi Y., Kisaka Y., Abe M., Ikeda Y., et al. Splenic elasticity measured with real-time tissue elastography is a marker of portal hypertension. Radiology 2011, 261:960-968.
45. de Franchis R. Revising consensus in portal hypertension: report of the Baveno V consensus workshop on methodology of diagnosis and therapy in portal hypertension. J Hepatol 2010, 53:762-768.
46. D'Amico G., Garcia-Tsao G., Pagliaro L. Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies. J Hepatol 2006, 44:217-231.
47. Kazemi F., Kettaneh A., N'kontchou G., Pinto E., Ganne-Carrie N., Trinchet J.C., et al. Liver stiffness measurement selects patients with cirrhosis at risk of bearing large oesophageal varices. J Hepatol 2006, 45:230-235.
48. Bureau C., Metivier S., Peron J.M., Robic M.A., Rouquet O., Dupuis E., et al. Prospective assessment of liver stiffness for the non-invasive prediction of portal hypertension. J Hepatol 2007, 46:S34.
49. Pritchett S., Cardenas A., Manning D., Curry M., Afdhal N.H. The optimal cut-off for predicting large oesophageal varices using transient elastography is disease specific. J Viral Hepat 2011, 18:e75-e80.
50. Kim B.K., Kim Y., Han K.H., Park J.Y., Kim J.K., Paik Y.H., et al. Risk assessment of esophageal variceal bleeding in B-viral liver cirrhosis by a liver stiffness measurement-based model. Am J Gastroenterol 2011, 106:1654-1662. 1730.
51. Kim B.K., Han K.H., Park J.Y., Ahn S.H., Kim J.K., Paik Y.H., et al. A liver stiffness measurement-based, noninvasive prediction model for high-risk esophageal varices in B-viral liver cirrhosis. Am J Gastroenterol 2010, 105:1382-1390.
52. Germani G., Hytiroglou P., Fotiadu A., Burroughs A.K., Dhillon A.P. Assessment of fibrosis and cirrhosis in liver biopsies: an update. Semin Liver Dis 2011, 31:82-90.
53. Desmet V.J., Roskams T. Cirrhosis reversal: a duel between dogma and myth. J Hepatol 2004, 40:860-867.
54. Mallet V., Gilgenkrantz H., Serpaggi J., Verkarre V., Vallet-Pichard A., Fontaine H., et al. Brief communication: the relationship of regression of cirrhosis to outcome in chronic hepatitis C. Ann Intern Med 2008, 149:399-403.
55. Rincon D., Ripoll C., Iacono O.L., Salcedo M., Catalina M.V., Alvarez E., et al. Antiviral therapy decreases hepatic venous pressure gradient in patients with chronic hepatitis C and advanced fibrosis. Am J Gastroenterol 2006, 101:2269-2274.
56. Roberts S., Gordon A., McLean C., Pedersen J., Bowden S., Thomson K., et al. Effect of sustained viral response on hepatic venous pressure gradient in hepatitis C-related cirrhosis. Clin Gastroenterol Hepatol 2007, 5:932-937.
57. Villanueva C., Aracil C., Colomo A., Hernandez-Gea V., Lopez-Balaguer J.M., Varez-Urturi C., et al. Acute hemodynamic response to beta-blockers and prediction of long-term outcome in primary prophylaxis of variceal bleeding. Gastroenterology 2009.
58. Turnes J., Garcia-Pagan J.C., Abraldes J.G., Hernandez-Guerra M., Dell'Era A., Bosch J. Pharmacological reduction of portal pressure and long-term risk of first variceal bleeding in patients with cirrhosis. Am J Gastroenterol 2006, 101:506-512.