MEK/ERK pathway mediates insulin-promoted degradation of MKP-3 protein in liver cells

Molecular and Cellular Endocrinology

Volumn 361, Issue 1-2, 2012, Pages 116-123

  Feng, Bin ^a,b   Jiao, Ping ^a,c   Yang, Zaiqing ^b   Xu, Haiyan ^a  

^a BROWN UNIVERSITY   (United States)

^b HUAZHONG AGRICULTURAL UNIVERSITY   (China)

^c JILIN UNIVERSITY   (China)

Author keywords

Glucose output; MAP kinase phosphatase; Protein degradation

Indexed keywords

CYCLOHEXIMIDE; DUAL SPECIFICITY PHOSPHATASE 6; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; G6PASE GENE; GENE; GENE EXPRESSION; GLUCONEOGENESIS; LIVER CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY;

ANIMALS; DUAL SPECIFICITY PHOSPHATASE 6; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; GLUCONEOGENESIS; GLUCOSE; GLUCOSE-6-PHOSPHATASE; HEPATOCYTES; HUMANS; INSULIN; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MUTANT PROTEINS; PHOSPHORYLATION; PROTEOLYSIS; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84864331936     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2012.03.025     Document Type: Article

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