Heterologous expression of human costimulatory molecule B7-2 and construction of B7-2 immobilized polyhydroxyalkanoate nanoparticles for use as an immune activation agent

BMC Biotechnology

Volumn 12, Issue , 2012, Pages

  Li, Ming Chuan ^a   Liu, Qian Qian ^a   Lu, Xiao Yun ^a   Zhang, Ya Li ^a   Wang, Lei Lei ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

B7 2; Costimulation; Immobilization; PHA nanoparticle; PhaP

Indexed keywords

ANTITUMOR IMMUNITY; B7-2; BINDING PROTEINS; BIOCOMPATIBLE POLYESTERS; COSTIMULATION; COSTIMULATORY MOLECULES; EXTRACELLULAR DOMAINS; HETEROLOGOUS EXPRESSION; HYDROPHOBIC INTERACTIONS; IMMUNE ACTIVATION; IN-VITRO; N-TERMINALS; NOVEL STRATEGIES; PHAP; POLY(3-HYDROXYBUTYRATE-CO-3-HYDROXYHEXANOATE) (PHBHHX); POLY-HYDROXYALKANOATE; POLYHYDROXYALKANOATES; RECOMBINANT ESCHERICHIA COLI; T CELL ACTIVATION; T CELLS;

CELLS; CYTOLOGY; ESCHERICHIA COLI; LOADING; MOLECULES; NANOPARTICLES; NANOSYSTEMS; RADIOACTIVE WASTE VITRIFICATION;

RECOMBINANT PROTEINS;

BINDING PROTEIN; CD86 ANTIGEN; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; PHA GRANULE BINDING PROTEIN PHASIN; POLY(3 HYDROXYBUTYRATE CO 3 HYDROXYHEXANOATE); POLYHYDROXYALKANOIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG MANUFACTURE; DRUG PURIFICATION; ESCHERICHIA COLI; HUMAN; HUMAN CELL; IMMUNOCOMPETENCE; PROTEIN DOMAIN; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION;

ANTIGENS, CD86; CELLS, CULTURED; ESCHERICHIA COLI; GENE EXPRESSION; HUMANS; IMMUNOLOGIC FACTORS; LYMPHOCYTE ACTIVATION; NANOPARTICLES; POLYHYDROXYALKANOATES; PROTEIN STRUCTURE, TERTIARY; T-LYMPHOCYTES;

ESCHERICHIA COLI;

EID: 84864329258     PISSN: None     EISSN: 14726750     Source Type: Journal    
DOI: 10.1186/1472-6750-12-43     Document Type: Article

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