Polycystic kidney disease: An early urea-selective urine-concentrating defect in ADPKD

Nature Reviews Nephrology

Volumn 8, Issue 8, 2012, Pages 437-439

  Bankir, Lise ^a   Bichet, Daniel G ^b  

^a CENTRE DE RECHERCHE DES CORDELIERS   (France)

^b HÔPITAL DU SACRÉ COEUR DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

COPEPTIN; UREA; VASOPRESSIN;

ARTICLE; EARLY DIAGNOSIS; GLOMERULUS FILTRATION RATE; HUMAN; KIDNEY CONCENTRATING CAPACITY; KIDNEY DYSFUNCTION; KIDNEY POLYCYSTIC DISEASE; OSMOREGULATION; PRIORITY JOURNAL; SODIUM BLOOD LEVEL;

BIOLOGICAL MARKERS; GLYCOPEPTIDES; HUMANS; POLYCYSTIC KIDNEY, AUTOSOMAL DOMINANT; UREA; VASOPRESSINS;

EID: 84864327554     PISSN: 17595061     EISSN: 1759507X     Source Type: Journal    
DOI: 10.1038/nrneph.2012.139     Document Type: Article

References (10)

1. Meijer, E., Boertien, W. E., Zietse, R. & Gansevoort, R. T. Potential deleterious effects of vasopressin in chronic kidney disease and particularly autosomal dominant polycystic kidney disease. Kidney Blood Press. Res. 34, 235-244 (2011).
2. Zittema, D. et al. Vasopressin, copeptin, and renal concentrating capacity in patients with autosomal dominant polycystic kidney disease without renal impairment. Clin. J. Am. Soc. Nephrol. 7, 906-913 (2012).
3. Ho, T. A. et al. Autosomal dominant polycystic kidney disease is associated with central and nephrogenic defects in osmoregulation. Kidney Int. (in press).
4. Fenton, R. A. Urea transporters and renal function: lessons from knockout mice. Curr. Opin. Nephrol. Hypertens. 17, 513-518 (2008).
5. Yang, B. & Bankir, L. Urea and urine concentrating ability: New insights from studies in mice. Am. J. Physiol. Renal Physiol. 288, F881-F896 (2005). (Pubitemid 40569752)
6. Bankir, L. & Yang, B. New insights into urea and glucose handling by the kidney, and the urine concentrating mechanism. Kidney Int. 81, 1179-1198 (2012).
7. Schlondorff, D. Renal prostaglandin synthesis. Sites of production and specific actions of prostaglandins. Am. J. Med. 81, 1-11 (1986).
8. Corey, H. E., Greifer, I., Greenstein, S. M., Tellis, V. & Spitzer, A. The fractional excretion of urea: A new diagnostic test for acute renal allograft rejection. Pediatr. Nephrol. 7, 268-272 (1993). (Pubitemid 23213987)
9. Miller, T. R. et al. Urinary diagnostic indices in acute renal failure: A prospective study. Ann. Intern. Med. 89, 47-50 (1978). (Pubitemid 8390144)
10. Bae, K. T. & Grantham, J. J. Imaging for the prognosis of autosomal dominant polycystic kidney disease. Nat. Rev. Nephrol. 6, 96-106 (2010).