Effect of physical states of binders on high-shear wet granulation and granule properties: A mechanistic approach toward understanding high-shear wet granulation process, part 3: Effect of binder rheological properties

Journal of Pharmaceutical Sciences

Volumn 101, Issue 5, 2012, Pages 1877-1887

  Li, Jinjiang ^a   Tao, Li ^a   Buckley, David ^a   Tao, Jing ^a   Gao, Julia ^a   Hubert, Mario ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Glass transition; Granulation; Moisture sorption; Phase transition; Polymers; Preformulation; Rheology; Solid dosage form; Sorption; Water sorption

Indexed keywords

GLASS; HYDROXYPROPYLCELLULOSE; POLYMER; POVIDONE; RUBBER; WATER; CELLULOSE; DRUG DERIVATIVE;

ARTICLE; BINDING AFFINITY; DRUG GRANULATION; FLOW KINETICS; HIGH SHEAR WET GRANULATION; PARTICLE SIZE; PHYSICAL CHEMISTRY; TABLET FRIABILITY; VISCOELASTICITY; CHEMISTRY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG FORMULATION; PHARMACEUTICS;

CALORIMETRY, DIFFERENTIAL SCANNING; CELLULOSE; DRUG COMPOUNDING; PARTICLE SIZE; RHEOLOGY; TECHNOLOGY, PHARMACEUTICAL;

EID: 84864321890     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23059     Document Type: Article

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