A multiphoton microscope platform for imaging the mouse eye

Molecular Vision

Volumn 18, Issue , 2012, Pages 1840-1848

  Masihzadeh, Omid ^a   Lei, Tim C ^a   Ammar, David A ^b   Kahook, Malik Y ^b   Gibson, Emily A ^a  

^a The University of Colorado Denver   (United States)

^b UNIVERSITY OF COLORADO HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL TISSUE; ANTERIOR EYE CHAMBER; ARTICLE; AUTOFLUORESCENCE IMAGING; CONJUNCTIVA; CORNEA ENDOTHELIUM; CORNEA EPITHELIUM; ENUCLEATION; EYE EXAMINATION; HISTOLOGY; IMAGE ANALYSIS; IMAGE QUALITY; IMAGE RECONSTRUCTION; IMAGING SYSTEM; IN VIVO STUDY; IRIS; MOUSE; MULTIPHOTON MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; THREE DIMENSIONAL IMAGING; TRABECULAR MESHWORK;

ANIMALS; ANTERIOR CHAMBER; CONJUNCTIVA; CORNEA; IMAGING, THREE-DIMENSIONAL; IRIS; MICE; MICE, INBRED C57BL; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; SCLERA; TRABECULAR MESHWORK;

EID: 84864321378     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Aihara M, Lindsey JD, Weinreb RN. Aqueous humor dynamics in mice. Invest Ophthalmol Vis Sci 2003; 44:5168-73. [PMID: 14638713]
2. Lei Y, Overby DR, Boussommier-Calleja A, Stamer WD, Ethier CR. Outflow Physiology of the Mouse Eye: Pressure Dependence and Washout. Invest Ophthalmol Vis Sci 2011; 52:1865-71. [PMID: 21169533]
3. Johnson M. 'What controls aqueous humour outflow resistance?'. Exp Eye Res 2006; 82:545-57. [PMID: 16386733]
4. Irshad FA, Mayfield MS, Zurakowski D, Ayyala RS. Variation in Schlemm's Canal Diameter and Location by Ultrasound Biomicroscopy. Ophthalmology 2010; 117:916-20. [PMID: 20079926]
5. Leung CK, Li H, Weinreb RN, Liu J, Cheung CY, Lai RY, Pang CP, Lam DS. Anterior chamber angle measurement with anterior segment optical coherence tomography: a comparison between slit lamp OCT and Visante OCT. Invest Ophthalmol Vis Sci 2008; 49:3469-74. [PMID: 18408181]
6. Kagemann L, Wollstein G, Ishikawa H, Sigal IA, Folio LS, Xu J, Gong HY, Schuman JS. Identification and Assessment of Schlemm's Canal by Spectral-Domain Optical Coherence Tomography. Invest Ophthalmol Vis Sci 2010; 51:4054-9. [PMID: 20237244]
7. Kagemann L, Wollstein G, Ishikawa H, Sigal IA, Folio LS, Xu J, Gong H, Schuman JS. 3D visualization of aqueous humor outflow structures in-situ in humans. Exp Eye Res 2011; 93:308-15. [PMID: 21514296]
8. Hann CR, Bentley MD, Vercnocke A, Ritman EL, Fautsch MP. Imaging the aqueous humor outflow pathway in human eyes by three-dimensional micro-computed tomography (3D micro-CT). Exp Eye Res 2011; 92:104-11. [PMID: 21187085]
9. Masihzadeh O, Ammar DA, Lei TC, Gibson EA, Kahook MY. Real-time measurements of nicotinamide adenine dinucleotide in live human trabecular meshwork cells: Effects of acute oxidative stress. Exp Eye Res 2011; 93:316-20. [PMID: 21354135]
10. Alvarado J, Murphy C, Juster R. Trabecular meshwork cellularity in primary open-angle glaucoma and nonglaucomatous normals. Ophthalmology 1984; 91:564-79. [PMID: 6462622]
11. Rohen JW, Lutjendrecoll E, Flugen C, Meyer M, Grierson I. Ultrastructure of the trabecular meshwork in untreated cases of primary open-angle glaucoma (POGA). Exp Eye Res 1993; 56:683-92. [PMID: 8595810]
12. Allingham RR, deKater A, Ethier C. Schlemm's canal and primary open angle glaucoma: Correlation between Schlemm's canal dimensions and outflow facility. Exp Eye Res 1996; 62:101-9. [PMID: 8674505]
13. Ammar DA, Lei TC, Gibson EA, Kahook MY. Two-photon imaging of the trabecular meshwork. Mol Vis 2010; 16:935-44. [PMID: 20596237]
14. Ammar DA, Lei TC, Masihzadeh O, Gibson EA, Kahook MY. Trans-scleral imaging of the human trabecular meshwork by two-photon microscopy. Mol Vis 2011; 17:583-90. [PMID: 21386924]
15. Johnson AW, Ammar DA, Kahook MY. Two-Photon Imaging of the Mouse Eye. Invest Ophthalmol Vis Sci 2011; 52:4098-105. [PMID: 21447675]
16. Lei TC, Ammar DA, Masihzadeh O, Gibson EA, Kahook MY. Label-free imaging of trabecular meshwork cells using Coherent Anti-Stokes Raman Scattering (CARS) microscopy. Mol Vis 2011; 17:2628-33. [PMID: 22025898]
17. Gibson EA, Masihzadeh O, Lei TC, Ammar DA, Kahook MY. Multiphoton microscopy for ophthalmic imaging. J Ophthalmol 2011; 2011:870879. [PMID: 21274261]
18. Imanishi Y, Batten M, Piston D, Baehr W, Palczewski K. Noninvasive two-photon imaging reveals retinyl ester storage structures in the eye. J Cell Biol 2004; 164:373-83. [PMID: 14745001]
19. Yeh AT, Nassif N, Zoumi A, Tromberg B. Selective corneal imaging using combined second-harmonic generation and two-photon excited fluorescence. Opt Lett 2002; 27:2082-4. [PMID: 18033448]
20. Steven P, Muller M, Koop N, Rose C, Huttmann G. Comparison of Cornea Module and DermaInspect for noninvasive imaging of ocular surface pathologies. J Biomed Opt 2009; 14:064040. [PMID: 20059278]
21. Lyubovitsky JG, Spencer J, Krasieva T, Andersen B, Tromberg B. Imaging corneal pathology in a transgenic mouse model using nonlinear microscopy. J Biomed Opt 2006; 11:014013. [PMID: 16526890]
22. La Schiazza O, Bille JF. High-speed two-photon excited autofluorescence imaging of ex vivo human retinal pigment epithelial cells toward age-related macular degeneration diagnostic. J Biomed Opt 2008; 13:064008. [PMID: 19123655]
23. Wang B-G, Koenig K, Riemann I, Krieg R, Halbhuber K-J. Intraocular multiphoton microscopy with subcellular spatial resolution by infrared femtosecond lasers. Histochem Cell Biol 2006; 126:507-15. [PMID: 16673095]
24. Piston D, Masters B, Webb W. 3-Dimensionally resolved NAD(P)H cellular metabolic redox imaging of the in-situ cornea with 2-photon excitation laser-scanning microscopy. J Microsc 1995; 178:20-7. [PMID: 7745599]
25. Morishige N, Wahlert AJ, Kenney MC, Brown DJ, Kawamoto K, Chikama T-i, Nishida T, Jester JV. Second-harmonic imaging microscopy of normal human and keratoconus cornea. Invest Ophthalmol Vis Sci 2007; 48:1087-94. [PMID: 17325150]
26. Teng S, Tan H, Peng J, Lin H, Kim K, Lo W, Sun Y, Lin WC, Lin SJ, Jee SH, So PTC, Dong CY. Multiphoton autofluorescence and second-harmonic generation imaging of the ex vivo porcine eye. Invest Ophthalmol Vis Sci 2006; 47:1216-24. [PMID: 16505061]
27. Aptel F, Olivier N, Deniset-Besseau A, Legeais J-M, Plamann K, Schanne-Klein M-C, Beaurepaire E. Multimodal nonlinear imaging of the human cornea. Invest Ophthalmol Vis Sci 2010; 51:2459-65. [PMID: 20071677]
28. Zipfel WR, Williams RM, Christie R, Nikitin AY, Hyman BT, Webb WW. Live tissue intrinsic emission microscopy using multiphoton-excited native fluorescence and second harmonic generation. Proc Natl Acad Sci USA 2003; 100:7075-80. [PMID: 12756303]
29. Campagnola PJ, Millard AC, Terasaki M, Hoppe PE, Malone CJ, Mohler WA. Three-dimensional high-resolution secondharmonic generation imaging of endogenous structural proteins in biological tissues. Biophys J 2002; 82:493-508. [PMID: 11751336]
30. Squier J, Muller M. High resolution nonlinear microscopy: A review of sources and methods for achieving optimal imaging. Rev Sci Instrum 2001; 72:2855-67.
31. Helmchen F, Denk W. Deep tissue two-photon microscopy. Nat Methods 2005; 2:932-40. [PMID: 16299478]
32. Trebino R, DeLong KW, Fittinghoff DN, Sweetser JN, Krumbugel MA, Richman BA, Kane DJ. Measuring ultrashort laser pulses in the time-frequency domain using frequency-resolved optical gating. Rev Sci Instrum 1997; 68:3277-95.
33. Steven P, Bock F, Huttmann G, Cursiefen C. Intravital twophoton microscopy of immune cell dynamics in corneal lymphatic vessels. PLoS ONE 2011; 6:e26253. [PMID: 22028842]
34. Zipfel WR, Williams RM, Webb WW. Nonlinear magic: multiphoton microscopy in the biosciences. Nat Biotechnol 2003; 21:1369-77. [PMID: 14595365]
35. Bueno JM, Gualda EJ, Artal P. Adaptive optics multiphoton microscopy to study ex vivo ocular tissues. J Biomed Opt 2010; 15:066004. [PMID: 21198178]
36. Gonzalez JM Jr, Heur M, Tan JC. Two-photon Immunofluorescence Characterization of the Trabecular Meshwork In situ. Invest Ophthalmol Vis Sci. 2012 [PMID: 22531697]