TGF-beta1 increases cell rigidity by enhancing expression of smooth muscle actin: Keloid-derived fibroblasts as a model for cellular mechanics

Journal of Dermatological Science

Volumn 67, Issue 3, 2012, Pages 173-180

  Lee, Chih Hung ^a,b   Hong, Chien Hui ^c   Chen, Ying Ting ^a,b   Chen, Yu Chien ^d   Shen, Meng Ru ^d  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MUNICIPAL HSIAO KANG HOSPITAL   (Taiwan)

^c KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^d NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Cell rigidity; Keloid; SMA; TGF beta1; TGF beta1 receptor

Indexed keywords

PROTEIN KINASE INHIBITOR; SHORT HAIRPIN RNA; SMOOTH MUSCLE ACTIN; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; ARTICLE; ATOMIC FORCE MICROSCOPY; CELL RIGIDITY; CELLULAR PARAMETERS; CLINICAL ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FEMALE; FIBROBLAST; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; IMMUNOFLUORESCENCE; KELOID; MALE; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; WESTERN BLOTTING;

ACTINS; ADULT; CASE-CONTROL STUDIES; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; KELOID; MALE; MICROSCOPY, ATOMIC FORCE; MICROSCOPY, CONFOCAL; MIDDLE AGED; MUSCLE, SMOOTH; RNA INTERFERENCE; STRESS, MECHANICAL; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84864315010     PISSN: 09231811     EISSN: 1873569X     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2012.06.004     Document Type: Article

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