-
1
-
-
2942615282
-
Polo-like kinases and the orchestration of cell division
-
Barr F.A., Sillje H.H., Nigg E.A. Polo-like kinases and the orchestration of cell division. Nat Rev Mol Cell Biol 2004, 5:429-440.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 429-440
-
-
Barr, F.A.1
Sillje, H.H.2
Nigg, E.A.3
-
2
-
-
0034673537
-
Polo-like kinase1, a new target for antisense tumor therapy
-
Elez R., Piiper A., Giannini C.D., Brendel M., Zeuzem S. Polo-like kinase1, a new target for antisense tumor therapy. Biochem Biophys Res Commun 2000, 269:352-356.
-
(2000)
Biochem Biophys Res Commun
, vol.269
, pp. 352-356
-
-
Elez, R.1
Piiper, A.2
Giannini, C.D.3
Brendel, M.4
Zeuzem, S.5
-
3
-
-
0030462914
-
Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes
-
Lane H.A., Nigg E.A. Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes. J Cell Biol 1996, 135:1701-1713.
-
(1996)
J Cell Biol
, vol.135
, pp. 1701-1713
-
-
Lane, H.A.1
Nigg, E.A.2
-
4
-
-
13244271313
-
Polo-like kinases (Plks) and cancer
-
Takai N., Hamanaka R., Yoshimatsu J., Miyakawa I. Polo-like kinases (Plks) and cancer. Oncogene 2005, 24:287-291.
-
(2005)
Oncogene
, vol.24
, pp. 287-291
-
-
Takai, N.1
Hamanaka, R.2
Yoshimatsu, J.3
Miyakawa, I.4
-
5
-
-
17144393305
-
Progress in the discovery of polo-like kinase inhibitors
-
McInnes C., Mezna M., Fischer P.M. Progress in the discovery of polo-like kinase inhibitors. Curr Top Med Chem 2005, 5:181-197.
-
(2005)
Curr Top Med Chem
, vol.5
, pp. 181-197
-
-
McInnes, C.1
Mezna, M.2
Fischer, P.M.3
-
6
-
-
2942544699
-
Cancer inhibition in nude mice after systemic application of U6 promoter-driven short hairpin RNAs against PLK1
-
Spankuch B., Matthess Y., Knecht R., Zimmer B., Kaufmann M., Strebhardt K. Cancer inhibition in nude mice after systemic application of U6 promoter-driven short hairpin RNAs against PLK1. J Natl Cancer Inst 2004, 96:862-872.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 862-872
-
-
Spankuch, B.1
Matthess, Y.2
Knecht, R.3
Zimmer, B.4
Kaufmann, M.5
Strebhardt, K.6
-
7
-
-
10744221449
-
The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain
-
Elia A.E., Rellos P., Haire L.F., Chao J.W., Ivins F.J., Hoepker K., et al. The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain. Cell 2003, 115:83-95.
-
(2003)
Cell
, vol.115
, pp. 83-95
-
-
Elia, A.E.1
Rellos, P.2
Haire, L.F.3
Chao, J.W.4
Ivins, F.J.5
Hoepker, K.6
-
8
-
-
33847680936
-
Molecular and structural basis of polo-like kinase 1 substrate recognition: implications in centrosomal localization
-
Garcia-Alvarez B., de Carcer G., Ibanez S., Bragado-Nilsson E., Montoya G. Molecular and structural basis of polo-like kinase 1 substrate recognition: implications in centrosomal localization. Proc Natl Acad Sci U S A 2007, 104:3107-3112.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 3107-3112
-
-
Garcia-Alvarez, B.1
de Carcer, G.2
Ibanez, S.3
Bragado-Nilsson, E.4
Montoya, G.5
-
9
-
-
0037427082
-
Tumor regression by combination antisense therapy against Plk1 and Bcl-2
-
Elez R., Piiper A., Kronenberger B., Kock M., Brendel M., Hermann E., et al. Tumor regression by combination antisense therapy against Plk1 and Bcl-2. Oncogene 2003, 22:69-80.
-
(2003)
Oncogene
, vol.22
, pp. 69-80
-
-
Elez, R.1
Piiper, A.2
Kronenberger, B.3
Kock, M.4
Brendel, M.5
Hermann, E.6
-
10
-
-
33847403132
-
In vitro biological activity of a novel small-molecule inhibitor of polo-like kinase 1
-
Lansing T.J., McConnell R.T., Duckett D.R., Spehar G.M., Knick V.B., Hassler D.F., et al. In vitro biological activity of a novel small-molecule inhibitor of polo-like kinase 1. Mol Cancer Ther 2007, 6:450-459.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 450-459
-
-
Lansing, T.J.1
McConnell, R.T.2
Duckett, D.R.3
Spehar, G.M.4
Knick, V.B.5
Hassler, D.F.6
-
11
-
-
59049093510
-
Deficiency in chromosome congression by the inhibition of Plk1 polo box domain-dependent recognition
-
Watanabe N., Sekine T., Takagi M., Iwasaki J., Imamoto N., Kawasaki H., et al. Deficiency in chromosome congression by the inhibition of Plk1 polo box domain-dependent recognition. J Biol Chem 2009, 284:2344-2353.
-
(2009)
J Biol Chem
, vol.284
, pp. 2344-2353
-
-
Watanabe, N.1
Sekine, T.2
Takagi, M.3
Iwasaki, J.4
Imamoto, N.5
Kawasaki, H.6
-
12
-
-
0038624074
-
Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells
-
Liu X., Erikson R.L. Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells. Proc Natl Acad Sci U S A 2003, 100:5789-5794.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 5789-5794
-
-
Liu, X.1
Erikson, R.L.2
-
13
-
-
31144436811
-
Inhibitory effect of polo-like kinase 1 depletion on mitosis and apoptosis of gastric cancer cells
-
Chen X.H., Lan B., Qu Y., Zhang X.Q., Cai Q., Liu B.Y., et al. Inhibitory effect of polo-like kinase 1 depletion on mitosis and apoptosis of gastric cancer cells. World J Gastroenterol 2006, 12:29-35.
-
(2006)
World J Gastroenterol
, vol.12
, pp. 29-35
-
-
Chen, X.H.1
Lan, B.2
Qu, Y.3
Zhang, X.Q.4
Cai, Q.5
Liu, B.Y.6
-
14
-
-
16844369144
-
Small interfering RNA-mediated Polo-like kinase 1 depletion preferentially reduces the survival of p53-defective, oncogenic transformed cells and inhibits tumor growth in animals
-
Guan R., Tapang P., Leverson J.D., Albert D., Giranda V.L., Luo Y. Small interfering RNA-mediated Polo-like kinase 1 depletion preferentially reduces the survival of p53-defective, oncogenic transformed cells and inhibits tumor growth in animals. Cancer Res 2005, 65:2698-2704.
-
(2005)
Cancer Res
, vol.65
, pp. 2698-2704
-
-
Guan, R.1
Tapang, P.2
Leverson, J.D.3
Albert, D.4
Giranda, V.L.5
Luo, Y.6
-
15
-
-
20144387142
-
Intravesical administration of small interfering RNA targeting PLK-1 successfully prevents the growth of bladder cancer
-
Nogawa M., Yuasa T., Kimura S., Tanaka M., Kuroda J., Sato K., et al. Intravesical administration of small interfering RNA targeting PLK-1 successfully prevents the growth of bladder cancer. J Clin Invest 2005, 115:978-985.
-
(2005)
J Clin Invest
, vol.115
, pp. 978-985
-
-
Nogawa, M.1
Yuasa, T.2
Kimura, S.3
Tanaka, M.4
Kuroda, J.5
Sato, K.6
-
16
-
-
33644767315
-
Normal cells, but not cancer cells, survive severe Plk1 depletion
-
Liu X., Lei M., Erikson R.L. Normal cells, but not cancer cells, survive severe Plk1 depletion. Mol Cell Biol 2006, 26:2093-2108.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2093-2108
-
-
Liu, X.1
Lei, M.2
Erikson, R.L.3
-
17
-
-
68249137199
-
Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1
-
Yun S.M., Moulaei T., Lim D., Bang J.K., Park J.E., Shenoy S.R., et al. Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1. Nat Struct Mol Biol 2009, 16:876-882.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 876-882
-
-
Yun, S.M.1
Moulaei, T.2
Lim, D.3
Bang, J.K.4
Park, J.E.5
Shenoy, S.R.6
-
18
-
-
0028362876
-
Requirement of vascular integrin alpha v beta 3 for angiogenesis
-
Brooks P.C., Clark R.A., Cheresh D.A. Requirement of vascular integrin alpha v beta 3 for angiogenesis. Science 1994, 264:569-571.
-
(1994)
Science
, vol.264
, pp. 569-571
-
-
Brooks, P.C.1
Clark, R.A.2
Cheresh, D.A.3
-
19
-
-
0029610677
-
Definition of two angiogenic pathways by distinct alpha v integrins
-
Friedlander M., Brooks P.C., Shaffer R.W., Kincaid C.M., Varner J.A., Cheresh D.A. Definition of two angiogenic pathways by distinct alpha v integrins. Science 1995, 270:1500-1502.
-
(1995)
Science
, vol.270
, pp. 1500-1502
-
-
Friedlander, M.1
Brooks, P.C.2
Shaffer, R.W.3
Kincaid, C.M.4
Varner, J.A.5
Cheresh, D.A.6
-
20
-
-
33646468932
-
Reevaluation of P-selectin and alpha 4 integrin as targets for the treatment of experimental autoimmune encephalomyelitis
-
Kerfoot S.M., Norman M.U., Lapointe B.M., Bonder C.S., Zbytnuik L., Kubes P. Reevaluation of P-selectin and alpha 4 integrin as targets for the treatment of experimental autoimmune encephalomyelitis. J Immunol 2006, 176:6225-6234.
-
(2006)
J Immunol
, vol.176
, pp. 6225-6234
-
-
Kerfoot, S.M.1
Norman, M.U.2
Lapointe, B.M.3
Bonder, C.S.4
Zbytnuik, L.5
Kubes, P.6
-
21
-
-
12144287687
-
18F-labeled RGD peptide: initial evaluation for imaging brain tumor angiogenesis
-
Chen X., Park R., Shahinian A.H., Tohme M., Khankaldyyan V., Bozorgzadeh M.H., et al. 18F-labeled RGD peptide: initial evaluation for imaging brain tumor angiogenesis. Nucl Med Biol 2004, 31:179-189.
-
(2004)
Nucl Med Biol
, vol.31
, pp. 179-189
-
-
Chen, X.1
Park, R.2
Shahinian, A.H.3
Tohme, M.4
Khankaldyyan, V.5
Bozorgzadeh, M.H.6
-
22
-
-
33947693246
-
Evaluation of a (99m) Tc-labeled cyclic RGD tetramer for noninvasive imaging integrin alpha(v)beta3-positive breast cancer
-
Liu S., Hsieh W.Y., Jiang Y., Kim Y.S., Sreerama S.G., Chen X., et al. Evaluation of a (99m) Tc-labeled cyclic RGD tetramer for noninvasive imaging integrin alpha(v)beta3-positive breast cancer. Bioconjug Chem 2007, 18:438-446.
-
(2007)
Bioconjug Chem
, vol.18
, pp. 438-446
-
-
Liu, S.1
Hsieh, W.Y.2
Jiang, Y.3
Kim, Y.S.4
Sreerama, S.G.5
Chen, X.6
-
23
-
-
28744442266
-
MR molecular imaging and fluorescence microscopy for identification of activated tumor endothelium using a bimodal lipidic nanoparticle
-
Mulder W.J., Strijkers G.J., Habets J.W., Bleeker E.J., van der Schaft D.W., Storm G., et al. MR molecular imaging and fluorescence microscopy for identification of activated tumor endothelium using a bimodal lipidic nanoparticle. FASEB J 2005, 19:2008-2010.
-
(2005)
FASEB J
, vol.19
, pp. 2008-2010
-
-
Mulder, W.J.1
Strijkers, G.J.2
Habets, J.W.3
Bleeker, E.J.4
van der Schaft, D.W.5
Storm, G.6
-
24
-
-
83755168263
-
In vivo near-infrared fluorescence imaging of integrin alpha2beta1 in prostate cancer with cell-penetrating-peptide-conjugated DGEA probe
-
Huang C.W., Li Z., Conti P.S. In vivo near-infrared fluorescence imaging of integrin alpha2beta1 in prostate cancer with cell-penetrating-peptide-conjugated DGEA probe. J Nucl Med 2011, 52:1979-1986.
-
(2011)
J Nucl Med
, vol.52
, pp. 1979-1986
-
-
Huang, C.W.1
Li, Z.2
Conti, P.S.3
-
25
-
-
7444235966
-
In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in brain tumor xenografts
-
Chen X., Conti P.S., Moats R.A. In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in brain tumor xenografts. Cancer Res 2004, 64:8009-8014.
-
(2004)
Cancer Res
, vol.64
, pp. 8009-8014
-
-
Chen, X.1
Conti, P.S.2
Moats, R.A.3
-
26
-
-
0842263619
-
MicroPET and autoradiographic imaging of breast cancer alpha v-integrin expression using 18F- and 64Cu-labeled RGD peptide
-
Chen X., Park R., Tohme M., Shahinian A.H., Bading J.R., Conti P.S. MicroPET and autoradiographic imaging of breast cancer alpha v-integrin expression using 18F- and 64Cu-labeled RGD peptide. Bioconjug Chem 2004, 15:41-49.
-
(2004)
Bioconjug Chem
, vol.15
, pp. 41-49
-
-
Chen, X.1
Park, R.2
Tohme, M.3
Shahinian, A.H.4
Bading, J.R.5
Conti, P.S.6
-
27
-
-
0036829759
-
Tumor targeting with radiolabeled alpha(v)beta(3) integrin binding peptides in a nude mouse model
-
Janssen M.L., Oyen W.J., Dijkgraaf I., Massuger L.F., Frielink C., Edwards D.S., et al. Tumor targeting with radiolabeled alpha(v)beta(3) integrin binding peptides in a nude mouse model. Cancer Res 2002, 62:6146-6151.
-
(2002)
Cancer Res
, vol.62
, pp. 6146-6151
-
-
Janssen, M.L.1
Oyen, W.J.2
Dijkgraaf, I.3
Massuger, L.F.4
Frielink, C.5
Edwards, D.S.6
-
28
-
-
0347926091
-
Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities
-
Saito G., Swanson J.A., Lee K.D. Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities. Adv Drug Deliv Rev 2003, 55:199-215.
-
(2003)
Adv Drug Deliv Rev
, vol.55
, pp. 199-215
-
-
Saito, G.1
Swanson, J.A.2
Lee, K.D.3
-
29
-
-
0033922714
-
Penetration of protein toxins into cells
-
Falnes P.O., Sandvig K. Penetration of protein toxins into cells. Curr Opin Cell Biol 2000, 12:407-413.
-
(2000)
Curr Opin Cell Biol
, vol.12
, pp. 407-413
-
-
Falnes, P.O.1
Sandvig, K.2
-
30
-
-
0034799442
-
Increased human polo-like kinase-1 expression in gliomas
-
Dietzmann K., Kirches E., von B., Jachau K., Mawrin C. Increased human polo-like kinase-1 expression in gliomas. J Neurooncol 2001, 53:1-11.
-
(2001)
J Neurooncol
, vol.53
, pp. 1-11
-
-
Dietzmann, K.1
Kirches, E.2
von, B.3
Jachau, K.4
Mawrin, C.5
|