The activation state of macrophages alters their ability to suppress preadipocyte apoptosis

Journal of Endocrinology

Volumn 214, Issue 1, 2012, Pages 21-29

  Molgat, André S D ^a,b   Gagnon, AnneMarie ^a,b   Foster, Charlie ^a,b   Sorisky, Alexander ^a,b  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 4; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN KINASE B; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROADIPOCYTE;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; APOPTOSIS; CELL LINE; CELL SURVIVAL; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; HUMANS; IMMUNOBLOTTING; INTERLEUKIN-4; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84864298065     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1530/JOE-12-0114     Document Type: Article

References (37)

1. Alkhouri N, Gornicka A, Berk MP, Thapaliya S, Dixon LJ, Kashyap S, Schauer PR & Feldstein AE 2010 Adipocyte apoptosis, a link between obesity, insulin resistance, and hepatic steatosis. Journal of Biological Chemistry 285 3428-3438. (doi:10.1074/jbc.M109.074252)
2. Arner E, Westermark PO, Spalding KL, Britton T, Ryden M, Frisen J, Bernard S & Arner P 2010 Adipocyte turnover: relevance to human adipose tissue morphology. Diabetes 59 105-109. (doi:10.2337/db09-0942)
3. Artemenko Y, Gagnon A, Aubin D & Sorisky A 2005 Anti-adipogenic effect of PDGF is reversed by PKC inhibition. Journal of Cellular Physiology 204 646-653. (doi:10.1002/jcp.20314)
4. Chau H, Mirtsos C & Huang HL 2011 Regulation of death complexes formation in tumor necrosis factor receptor signaling. Experimental Cell Research 317 1841-1850. (doi:10.1016/j.yexcr.2011.05.015)
5. Constant VA, Gagnon A, Landry A & Sorisky A 2006 Macrophageconditioned medium inhibits the differentiation of 3T3-L1 and human abdominal preadipocytes. Diabetologia 49 1402-1411. (doi:10.1007/ s00125-006-0253-0)
6. Daigneault M, Preston JA, Marriott HM, Whyte MK & Dockrell DH 2010 The identification of markers of macrophage differentiation in PMAstimulated THP-1 cells and monocyte-derived macrophages. PLoS ONE 5 e8668. (doi:10.1371/journal.pone.0008668)
7. Fischer-Posovszky P, Tornqvist H, Debatin KM & Wabitsch M 2004 Inhibition of death-receptor mediated apoptosis in human adipocytes by the insulin-like growth factor I (IGF-I)/IGF-I receptor autocrine circuit. Endocrinology 145 1849-1859. (doi:10.1210/en.2003-0985)
8. Fischer-Posovszky P, Keuper M, Nagel S, Hesse D, Schurmann A, Debatin KM, Strauss G & Wabitsch M 2011 Downregulation of FLIP by cycloheximide sensitizes human fat cells to CD95-induced apoptosis. Experimental Cell Research 317 2200-2209. (doi:10.1016/j.yexcr. 2011.06.016)
9. Gordon S & Martinez FO 2010 Alternative activation of macrophages: mechanism and functions. Immunity 32 593-604. (doi:10.1016/j.immuni. 2010.05.007)
10. Heilbronn L, Smith SR & Ravussin E 2004 Failure of fat cell proliferation, mitochondrial function and fat oxidation results in ectopic fat storage, insulin resistance and type II diabetes mellitus. International Journal of Obesity and Related Metabolic Disorders 28 (Suppl 4) S12-S21. (doi:10.1038/sj.ijo. 0802853)
11. Ide J, Gagnon A, Molgat AS, Landry A, Foster C & Sorisky A 2011 Macrophage-conditioned medium inhibits the activation of cyclindependent kinase 2 by adipogenic inducers in 3T3-L1 preadipocytes. Journal of Cellular Physiology 226 2297-2306. (doi:10.1002/jcp.22566)
12. Jozefowski S, Czerkies M, Lukasik A, Bielawska A, Bielawski J, Kwiatkowska K & Sobota A 2010 Ceramide and ceramide 1-phosphate are negative regulators of TNF-a production induced by lipopolysaccharide. Journal of Immunology 185 6960-6973. (doi:10.4049/ jimmunol.0902926)
13. Keuper M, Bluher M, Schon MR, Moller P, Dzyakanchuk A, Amrein K, Debatin KM, Wabitsch M & Fischer-Posovszky P 2011 An inflammatory micro-environment promotes human adipocyte apoptosis. Molecular and Cellular Endocrinology 339 105-113. (doi:10.1016/j.mce.2011. 04.004)
14. Kim JY, van de Wall E, Laplante M, Azzara A, Trujillo ME, Hofmann SM, Schraw T, Durand JL, Li H, Li G et al. 2007 Obesity-associated improvements in metabolic profile through expansion of adipose tissue. Journal of Clinical Investigation 117 2621-2637. (doi:10.1172/JCI31021)
15. Lacasa D, Taleb S, Keophiphath M, Miranville A & Clement K 2007 Macrophage-secreted factors impair human adipogenesis: involvement of proinflammatory state in preadipocytes. Endocrinology 148 868-877. (doi:10.1210/en.2006-0687)
16. Laemmli UK 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 680-685. (doi:10.1038/ 227680a0)
17. Lu C, Kumar PA, Fan Y, Sperling MA & Menon RK 2010 A novel effect of growth hormone on macrophage modulates macrophage-dependent adipocyte differentiation. Endocrinology 151 2189-2199. (doi:10.1210/en. 2009-1194)
18. Lumeng CN, Bodzin JL & Saltiel AR 2007 Obesity induces a phenotypic switch in adipose tissue macrophage polarization. Journal of Clinical Investigation 117 175-184. (doi:10.1172/JCI29881)
19. Lumeng CN, DelProposto JB, Westcott DJ & Saltiel AR 2008 Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes. Diabetes 57 3239-3246. (doi:10.2337/db08-0872)
20. Martinez FO, Gordon S, Locati M & Mantovani A 2006 Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. Journal of Immunology 177 7303-7311.
21. Maumus M, Sengenes C, Decaunes P, Zakaroff-Girard A, Bourlier V, Lafontan M, Galitzky J & Bouloumie A 2008 Evidence of in situ proliferation of adult adipose tissue-derived progenitor cells: influence of fat mass microenvironment and growth. Journal of Clinical Endocrinology and Metabolism 93 4098-4106. (doi:10.1210/jc.2008-0044)
22. Mayi TH, Duhem C, Copin C, Bouhlel MA, Rigamonti E, Pattou F, Staels B & Chinetti-Gbaguidi G 2010 Visfatin is induced by peroxisome proliferator-activated receptor gamma in human macrophages. FEBS Journal 277 3308-3320. (doi:10.1111/j.1742-4658.2010.07729.x)
23. Molgat AS, Gagnon A & Sorisky A 2009 Preadipocyte apoptosis is prevented by macrophage-conditioned medium in a PDGF-dependent manner. American Journal of Physiology. Cell Physiology 296 C757-C765. (doi:10.1152/ajpcell.00617.2008)
24. Molgat AS, Gagnon A & Sorisky A 2011 Macrophage-induced preadipocyte survival depends on signaling through Akt, ERK1/2, and reactive oxygen species. Experimental Cell Research 317 521-530. (doi:10.1016/j.yexcr.2010. 10.024)
25. Nagaoka I, Honma S, Someya A, Iwabuchi K & Yamashita T 1992 Differential expression of the platelet-derived growth factor-A and -B genes during maturation of monocytes to macrophages. Comparative Biochemistry and Physiology, Part B 103 349-356. (doi:10.1016/0305-0491(92)90303-9)
26. Niesler CU, Urso B, Prins JB & Siddle K 2000 IGF-I inhibits apoptosis induced by serum withdrawal, but potentiates TNF-a-induced apoptosis, in 3T3-L1 preadipocytes. Journal of Endocrinology 167 165-174. (doi:10.1677/joe.0.1670165)
27. Odegaard JI, Ricardo-Gonzalez RR, Goforth MH, Morel CR, Subramanian V, Mukundan L, Red Eagle A, Vats D, Brombacher F, Ferrante AW et al. 2007 Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance. Nature 447 1116-1120. (doi:10.1038/nature05894)
28. Papineau D, Gagnon A & Sorisky A 2003 Apoptosis of human abdominal preadipocytes before and after differentiation into adipocytes in culture. Metabolism 52 987-992. (doi:10.1016/S0026-0495 (03)00165-3)
29. Patsouris D, Li PP, Thapar D, Chapman J, Olefsky JM & Neels JG 2008 Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals. Cell Metabolism 8 301-309. (doi:10.1016/j.cmet. 2008.08.015)
30. Skolnik EY & Marcusohn J 1996 Inhibition of insulin receptor signaling by TNF: potential role in obesity and non-insulin-dependent diabetes mellitus. Cytokine & Growth Factor Reviews 7 161-173. (doi:10.1016/1359-6101(96)00021-4)
31. Stienstra R, Duval C, Keshtkar S, van der Laak J, Kersten S, Kersten S & Muller M 2008 Peroxisome proliferator-activated receptor gamma activation promotes infiltration of alternatively activated macrophages into adipose tissue. Journal of Biological Chemistry 283 22620-22627. (doi:10. 1074/jbc.M710314200)
32. Tchkonia T, Tchoukalova YD, Giorgadze N, Pirtskhalava T, Karagiannides I, Forse RA, Koo A, Stevenson M, Chinnappan D, Cartwright A et al. 2005 Abundance of two human preadipocyte subtypes with distinct capacities for replication, adipogenesis, and apoptosis varies among fat depots. American Journal of Physiology. Endocrinology and Metabolism 288 E267-E277. (doi:10.1152/ajpendo.00265.2004)
33. Tchoukalova Y, Koutsari C & Jensen M 2007 Committed subcutaneous preadipocytes are reduced in human obesity. Diabetologia 50 151-157. (doi:10.1007/s00125-006-0496-9)
34. Telepnev M, Golovliov I, Grundstrom T, Tarnvik A & Sjostedt A 2003 Francisella tularensis inhibits Toll-like receptor-mediated activation of intracellular signalling and secretion of TNF-a and IL-1 from murine macrophages. Cellular Microbiology 5 41-51. (doi:10.1046/j.1462-5822. 2003.00251.x)
35. Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL & Ferrante AW Jr 2003 Obesity is associated with macrophage accumulation in adipose tissue. Journal of Clinical Investigation 112 1796-1808. (doi:10.1172/JCI200319246)
36. Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, Sole J, Nichols A, Ross JS, Tartaglia LA et al. 2003 Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. Journal of Clinical Investigation 112 1821-1830. (doi:10.1172/JCI200319451)
37. Zhang HH, Kumar S, Barnett AH & Eggo MC 2001 Dexamethasone inhibits tumor necrosis factor-alpha-induced apoptosis and interleukin-1 beta release in human subcutaneous adipocytes and preadipocytes. Journal of Clinical Endocrinology and Metabolism 86 2817-2825. (doi:10.1210/jc.86.6.2817)