A phase IIa randomized controlled pilot study evaluating the safety and clinical outcomes following the use of rhGDF-5/β-TCP in regenerative periodontal therapy

Clinical Oral Investigations

Volumn 16, Issue 4, 2012, Pages 1181-1189

  Windisch, Péter ^a   Stavropoulos, Andreas ^b,c   Molnár, Bálint ^a   Szendröi Kiss, Dóra ^a   Szilágyi, Emese ^a   Rosta, Péter ^a   Horváth, Attila ^a   Capsius, Björn ^d   Wikesjö, Ulf M E ^e   Sculean, Anton ^f  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b AARHUS UNIVERSITY   (Denmark)

^c Center for Experimental and Preclinical Research (CEPBR)   (Greece)

^d Scil Technology GmbH   (Germany)

^e MEDICAL COLLEGE OF GEORGIA   (United States)

^f UNIVERSITY OF BERN   (Switzerland)

Author keywords

TCP; Clinical trial; Periodontal regeneration; Periodontal surgery; rhGDF 5; Tissue engineering

Indexed keywords

BETA-TRICALCIUM PHOSPHATE; BIOMATERIAL; CALCIUM PHOSPHATE; DRUG CARRIER; GROWTH DIFFERENTIATION FACTOR 5; RECOMBINANT PROTEIN;

ADULT; AGED; ALVEOLAR BONE LOSS; ANTIBODY PRODUCTION; ARTICLE; BLOOD; CHEMISTRY; CHRONIC PERIODONTITIS; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEBRIDEMENT; FEMALE; FOLLOW UP; GINGIVA DISEASE; HUMAN; IMMUNOLOGY; MALE; METHODOLOGY; MIDDLE AGED; PERIODONTAL DISEASE; PERIODONTAL POCKET; PERIODONTICS; PHASE 2 CLINICAL TRIAL; PILOT STUDY; RANDOMIZED CONTROLLED TRIAL; SAFETY; SURGICAL FLAPS; TOOTH PLAQUE; TOOTH RADIOGRAPHY; TREATMENT OUTCOME;

ADULT; AGED; ALVEOLAR BONE LOSS; ANTIBODY FORMATION; BIOCOMPATIBLE MATERIALS; CALCIUM PHOSPHATES; CHRONIC PERIODONTITIS; DEBRIDEMENT; DENTAL PLAQUE INDEX; DRUG CARRIERS; FEMALE; FOLLOW-UP STUDIES; GINGIVAL RECESSION; GROWTH DIFFERENTIATION FACTOR 5; GUIDED TISSUE REGENERATION, PERIODONTAL; HUMANS; MALE; MIDDLE AGED; PERIODONTAL ATTACHMENT LOSS; PERIODONTAL INDEX; PERIODONTAL POCKET; PILOT PROJECTS; RADIOGRAPHY, BITEWING; RECOMBINANT PROTEINS; SAFETY; SURGICAL FLAPS; TREATMENT OUTCOME;

EID: 84864288919     PISSN: 14326981     EISSN: 14363771     Source Type: Journal    
DOI: 10.1007/s00784-011-0610-3     Document Type: Article

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