The effects of HIV and combination antiretroviral therapy on white matter integrity

AIDS

Volumn 26, Issue 12, 2012, Pages 1501-1508

  Wright, Patrick W ^a   Heaps, Jodi M ^b   Shimony, Josh S ^c   Thomas, Jewell B ^a   Ances, Beau M ^a  

^a WASHINGTON UNIVERSITY   (United States)

^b UNIVERSITY OF MISSOURI ST LOUIS   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

centrum semiovale; combination antiretroviral therapy; corpus callosum; diffusion tensor imaging; HIV

Indexed keywords

NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR; PROTEINASE INHIBITOR;

ADULT; ARTICLE; CLINICAL ARTICLE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; CORPUS CALLOSUM; DIFFUSION TENSOR IMAGING; DISEASE ASSOCIATION; DRUG EFFECT; FEMALE; FRACTIONAL ANISOTROPY; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFLAMMATORY CELL; MALE; NEUROPSYCHOLOGICAL TEST; PATHOPHYSIOLOGY; PRIORITY JOURNAL; STATISTICAL ANALYSIS; WHITE MATTER LESION;

ADULT; ANTI-RETROVIRAL AGENTS; CASE-CONTROL STUDIES; CEREBRUM; CORPUS CALLOSUM; CROSS-SECTIONAL STUDIES; DIFFUSION TENSOR IMAGING; DRUG THERAPY, COMBINATION; FEMALE; HIV INFECTIONS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; LEUKOENCEPHALOPATHIES; MALE; NEUROPSYCHOLOGICAL TESTS;

EID: 84864288230     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0b013e3283550bec     Document Type: Article

References (52)

1. Ances BM, Ellis RJ. Dementia and neurocognitive disorders due to HIV-1 infection. Semin Neurol 2007; 27:86-92.
2. Narciso P, Galgani S, Del Grosso B, De Marco M, De Santis A, Balestra P, et al. Acute disseminated encephalomyelitis as manifestation of primary HIV infection. Neurology 2001; 57:1493-1496.
3. Cardenas VA, Meyerhoff DJ, Studholme C, Kornak J, Rothlind J, Lampiris H, et al. Evidence for ongoing brain injury in human immunodeficiency virus-positive patients treated with antiretroviral therapy. J Neurovirol 2009; 15:324-333.
4. Bohanna I, Georgiou-Karistianis N, Hannan AJ, Egan GF. Magnetic resonance imaging as an approach towards identifying neuropathological biomarkers for Huntington's disease. Brain Res Rev 2008; 58:209-225.
5. Ewers M, Frisoni GB, Teipel SJ, Grinberg LT, Amaro E Jr, Heinsen H, et al. Staging Alzheimer's disease progression with multimodality neuroimaging. Prog Neurobiol 2011; 95:535-546.
6. Sullivan EV, Rosenbloom MJ, Rohlfing T, Kemper CA, Deresinski S, Pfefferbaum A. Pontocerebellar contribution to postural instability and psychomotor slowing in HIV infection without dementia. Brain Imaging Behav 2011; 5:12-24.
7. Turner MR, Modo M. Advances in the application of MRI to amyotrophic lateral sclerosis. Expert Opin Med Diagn 2010; 4:483-496.
8. Chanraud S, Zahr N, Sullivan EV, Pfefferbaum A. MR diffusion tensor imaging: a window into white matter integrity of the working brain. Neuropsychol Rev 2010; 20:209-225.
9. Song S-K, Sun S-W, Ramsbottom MJ, Chang C, Russell J, Cross AH. Dysmyelination revealed through MRI as increased radial (but unchanged axial) diffusion of water. NeuroImage 2002; 17:1429-1436.
10. Kim JH, Loy DN, Liang HF, Trinkaus K, Schmidt RE, Song SK. Noninvasive diffusion tensor imaging of evolving white matter pathology in a mouse model of acute spinal cord injury. Magn Reson Med 2007; 58:253-260.
11. Naismith RT, Xu J, Tutlam NT, Trinkaus K, Cross AH, Song SK. Radial diffusivity in remote optic neuritis discriminates visual outcomes. Neurology 2010; 74:1702-1710.
12. Song S-K, Sun S-W, Ju W-K, Lin S-J, Cross AH, Neufeld AH. Diffusion tensor imaging detects and differentiates axon and myelin degeneration in mouse optic nerve after retinal ischemia. NeuroImage 2003; 20:1714-1722.
13. Filippi CG, Ulug AM, Ryan E, Ferrando SJ, van Gorp W. Diffusion tensor imaging of patients with HIV and normalappearing white matter on MR images of the brain. Am J Neuroradiol 2001; 22:277-283.
14. Gongvatana A, Schweinsburg BC, Taylor MJ, Theilmann RJ, Letendre SL, Alhassoon OM, et al. White matter tract injury and cognitive impairment in human immunodeficiency virusinfected individuals. J Neurovirol 2009; 15:187-195.
15. Gongvatana A, Cohen RA, Correia S, Devlin KN, Miles J, Kang H, et al. Clinical contributors to cerebral white matter integrity in HIV-infected individuals. J Neurovirol 2011; 17:477-486.
16. Kuper M, Rabe K, Esser S, Gizewski ER, Husstedt IW, Maschke M, et al. Structural gray and white matter changes in patients with HIV. J Neurol 2011; 258:1066-1075.
17. Li C, Zhang X, Komery A, Li Y, Novembre FJ, Herndon JG. Longitudinal diffusion tensor imaging and perfusion MRI investigation in a macaque model of neuro-AIDS: a preliminary study. Neuroimage 2011; 58:286-292.
18. Muller-Oehring EM, Schulte T, Rosenbloom MJ, Pfefferbaum A, Sullivan EV. Callosal degradation in HIV-1 infection predicts hierarchical perception: a DTI study. Neuropsychologia 2010; 48:1133-1143.
19. Pfefferbaum A, Rosenbloom MJ, Adalsteinsson E, Sullivan EV. Diffusion tensor imaging with quantitative fibre tracking in HIV infection and alcoholism comorbidity: synergistic white matter damage. Brain 2007; 130:48-64.
20. Pfefferbaum A, Rosenbloom MJ, Rohlfing T, Kemper CA, Deresinski S, Sullivan EV. Frontostriatal fiber bundle compromise in HIV infection without dementia. AIDS 2009; 23:1977-1985.
21. Pomara N, Crandall DT, Choi SJ, Johnson G, Lim KO. White matter abnormalities in HIV-1 infection: a diffusion tensor imaging study. Psychiatry Res 2001; 106:15-24.
22. Ragin AB, Storey P, Cohen BA, Epstein LG, Edelman RR. Whole brain diffusion tensor imaging in HIV-associated cognitive impairment. Am J Neuroradiol 2004; 25:195-200.
23. Ragin AB, Storey P, Cohen BA, Edelman RR, Epstein LG. Disease burden in HIV-associated cognitive impairment: a study of whole-brain imaging measures. Neurology 2004; 63:2293-2297.
24. Ragin AB, Wu Y, Storey P, Cohen BA, Edelman RR, Epstein LG. Diffusion tensor imaging of subcortical brain injury in patients infected with human immunodeficiency virus. J Neurovirol 2005; 11:292-298.
25. Stebbins GT, Smith CA, Bartt RE, Kessler HA, Adeyemi OM, Martin E, et al. HIV-associated alterations in normal-appearing white matter: a voxel-wise diffusion tensor imaging study. J Acquir Immune Defic Syndr 2007; 46:564-573.
26. Tate DF, Sampat M, Harezlak J, Fiecas M, Hogan J, Dewey J, et al. Regional areas and widths of the midsagittal corpus callosum among HIV-infected patients on stable antiretroviral therapies. J Neurovirol 2011; 17:368-379.
27. Thurnher MM, Castillo M, Stadler A, Rieger A, Schmid B, Sundgren PC. Diffusion-tensor MR imaging of the brain in human immunodeficiency virus-positive patients. Am J Neuroradiol 2005; 26:2275-2281.
28. Towgood KJ, Pitkanen M, Kulasegaram R, Fradera A, Kumar A, Soni S, et al. Mapping the brain in younger and older asymptomatic HIV-1 men: frontal volume changes in the absence of other cortical or diffusion tensor abnormalities. Cortex 2012; 48:230-241.
29. Wu Y, Storey P, Cohen BA, Epstein LG, Edelman RR, Ragin AB. Diffusion alterations in corpus callosum of patients with HIV. Am J Neuroradiol 2006; 27:656-660.
30. Chen Y, An H, Zhu H, Stone T, Smith JK, Hall C, et al. White matter abnormalities revealed by diffusion tensor imaging in nondemented and demented HIVR patients. Neuroimage 2009; 47:1154-1162.
31. Letendre SL, Ellis RJ, Ances BM, McCutchan JA. Neurologic complications of HIV disease and their treatment. Top HIV Med 2010; 18:45-55.
32. Antinori A, Arendt G, Becker JT, Brew BJ, Byrd DA, Cherner M, et al. Updated research nosology for HIV-associated neurocognitive disorders. Neurology 2007; 69:1789-1799.
33. Tross S, Price RW, Navia B, Thaler HT, Gold J, Hirsch DA, et al. Neuropsychological characterization of the AIDS dementia complex: a preliminary report. AIDS 1988; 2:81-88.
34. Van Gorp WG, Miller EN, Satz P, Visscher B. Neuropsychological performance in HIV-1 immunocompromised patients: a preliminary report. J Clin Experiment Neuropsychol 1989; 11:763-773.
35. Heaton RK, Grant I, Matthews CG. Comprehensive norms for an expanded Halstead-Reitan battery: demographic corrections, research findings, and clinical applications. Odessa, Fla. (P.O. Box 998, Odessa 33556): Psychological Assessment Resources; 1991.
36. Heaton RK, Franklin DR, Ellis RJ, McCutchan JA, Letendre SL, Leblanc S, et al. HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors. J Neurovirol 2011; 17:3-16.
37. Shimony JS, Burton H, Epstein AA, McLaren DG, Sun SW, Snyder AZ. Diffusion tensor imaging reveals white matter reorganization in early blind humans. Cereb Cortex 2006; 16:1653-1661.
38. Rowland DJ, Garbow JR, Laforest R, Snyder AZ. Registration of 18FFDG microPET and small-animal MRI. Nuclear Med Biol 2005; 32:567-572.
39. Lancaster JL, Glass TG, Lankipalli BR, Downs H, Mayberg H, Fox PT. A modality-independent approach to spatial normalization of tomographic images of the human brain. Human Brain Mapp 1995; 3:209-223.
40. Talairach J, Tournoux P. Co-planar stereotaxic atlas of the human brain: 3-dimensional proportional system: an approach to cerebral imaging. Stuttgart; New York: Georg Thieme; 1988.
41. Shimony JS, Sheline YI, D'Angelo G, Epstein AA, Benzinger TL, Mintun MA, et al. Diffuse microstructural abnormalities of normal-appearing white matter in late life depression: a diffusion tensor imaging study. Biol Psychiatry 2009; 66:245-252.
42. Basser PJ, Mattiello J, LeBihan D. Estimation of the effective self-diffusion tensor from the NMR spin echo. J Magn Reson B 1994; 103:247-254.
43. Chang L, Wong V, Nakama H, Watters M, Ramones D, Miller EN, et al. Greater than age-related changes in brain diffusion of HIV patients after 1 year. J Neuroimmune Pharmacol 2008; 3:265-274.
44. Bozzali M, Falini A, Franceschi M, Cercignani M, Zuffi M, Scotti G, et al. White matter damage in Alzheimer's disease assessed in vivo using diffusion tensor magnetic resonance imaging. J Neurol Neurosurg Psychiatry 2002; 72:742-746.
45. Rimkus Cde M, Junqueira Tde F, Lyra KP, Jackowski MP, Machado MA, Miotto EC, et al. Corpus callosum microstructural changes correlate with cognitive dysfunction in early stages of relapsing-remitting multiple sclerosis: axial and radial diffusivities approach. Mult Scler Int 2011; 2011:304875.
46. Stadnik TW, Chaskis C, Michotte A, Shabana WM, van Rompaey K, Luypaert R, et al. Diffusion-weighted MR imaging of intracerebral masses: comparison with conventional MR imaging and histologic findings. Am J Neuroradiol 2001; 22:969-976.
47. Guzman R, Barth A, Lovblad K-O, El-Koussy M, Weis J, Schroth G, et al. Use of diffusion-weighted magnetic resonance imaging in differentiating purulent brain processes from cystic brain tumors. J Neurosurg 2002; 97:1101-1107.
48. White DA, Connor LT, Nardos B, Shimony JS, Archer R, Snyder AZ, et al. Age-related decline in the microstructural integrity of white matter in children with early-and continuously-treated PKU: a DTI study of the corpus callosum. Mol Genet Metab 2010; 99 (Suppl 1):S41-S46.
49. Phillips MD, McGraw P, Lowe MJ, Mathews VP, Hainline BE. Diffusion-weighted imaging of white matter abnormalities in patients with phenylketonuria. Am J Neuroradiol 2001; 22:1583-1586.
50. Leuzzi V, Tosetti M, Montanaro D, Carducci C, Artiola C, Carducci C, et al. The pathogenesis of the white matter abnormalities in phenylketonuria. A multimodal 3.0 tesla MRI and magnetic resonance spectroscopy (1H MRS) study. J Inherit Metab Dis 2007; 30:209-216.
51. Kaul M, Garden GA, Lipton SA. Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature 2001; 410:988-994.
52. Wang Y, Wang Q, Haldar JP, Yeh FC, Xie M, Sun P, et al. Quantification of increased cellularity during inflammatory demyelination. Brain 2011; 134:3587-3598.