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Volumn 43, Issue 8, 2012, Pages 2264-2269

Oxygen imaging by MRI: Can blood oxygen level-dependent imaging depict the ischemic penumbra?

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYHEMOGLOBIN; OXYGEN;

EID: 84864283704     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.111.632455     Document Type: Review
Times cited : (31)

References (58)
  • 1
    • 60049091968 scopus 로고    scopus 로고
    • Penumbral selection of patients for trials of acute stroke therapy
    • Donnan GA, Baron JC, Ma H, Davis SM. Penumbral selection of patients for trials of acute stroke therapy. Lancet Neurol. 2009;8: 261-269.
    • (2009) Lancet Neurol , vol.8 , pp. 261-269
    • Donnan, G.A.1    Baron, J.C.2    Ma, H.3    Davis, S.M.4
  • 2
    • 77955163006 scopus 로고    scopus 로고
    • The concept of the penumbra: Can it be translated to stroke management?
    • Heiss WD. The concept of the penumbra: can it be translated to stroke management? Int J Stroke. 2010;5:290-295.
    • (2010) Int J Stroke , vol.5 , pp. 290-295
    • Heiss, W.D.1
  • 3
    • 0029814808 scopus 로고    scopus 로고
    • Spontaneous neurological recovery after stroke and the fate of the ischemic penumbra
    • Furlan M, Marchal G, Viader F, Derlon JM, Baron JC. Spontaneous neurological recovery after stroke and the fate of the ischemic penumbra. Ann Neurol. 1996;40:216-226.
    • (1996) Ann Neurol , vol.40 , pp. 216-226
    • Furlan, M.1    Marchal, G.2    Viader, F.3    Derlon, J.M.4    Baron, J.C.5
  • 5
  • 6
    • 85027935179 scopus 로고    scopus 로고
    • Rapid magnetic resonance measurement of global cerebral metabolic rate of oxygen consumption in humans during rest and hypercapnia
    • Jain V, Langham MC, Floyd TF, Jain G, Magland JF, Wehrli FW. Rapid magnetic resonance measurement of global cerebral metabolic rate of oxygen consumption in humans during rest and hypercapnia. J Cereb Blood Flow Metab. 2011;31:1504-1512.
    • (2011) J Cereb Blood Flow Metab , vol.31 , pp. 1504-1512
    • Jain, V.1    Langham, M.C.2    Floyd, T.F.3    Jain, G.4    Magland, J.F.5    Wehrli, F.W.6
  • 7
    • 84934441950 scopus 로고    scopus 로고
    • Potential application of (1)O MRI to human ischemic stroke
    • Delapaz R, Gupte P. Potential application of (1)O MRI to human ischemic stroke. Adv Exp Med Biol. 2011;701:215-222.
    • (2011) Adv Exp Med Biol , vol.701 , pp. 215-222
    • Delapaz, R.1    Gupte, P.2
  • 8
    • 0025630001 scopus 로고
    • Brain magnetic resonance imaging with contrast dependent on blood oxygenation
    • Ogawa S, Lee TM, Kay AR, Tank DW. Brain magnetic resonance imaging with contrast dependent on blood oxygenation. Proc Natl Acad Sci U S A. 1990;87:9868-9872.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 9868-9872
    • Ogawa, S.1    Lee, T.M.2    Kay, A.R.3    Tank, D.W.4
  • 9
    • 0019425420 scopus 로고
    • Reversal of focal 'misery-perfusion syndrome' by extra-intracranial arterial bypass in hemodynamic cerebral ischemia. A case study with 15O positron emission tomography
    • Baron JC, Bousser MG, Rey A, Guillard A, Comar D, Castaigne P. Reversal of focal 'misery-perfusion syndrome' by extra-intracranial arterial bypass in hemodynamic cerebral ischemia. A case study with 15O positron emission tomography. Stroke. 1981;12:454-459.
    • (1981) Stroke , vol.12 , pp. 454-459
    • Baron, J.C.1    Bousser, M.G.2    Rey, A.3    Guillard, A.4    Comar, D.5    Castaigne, P.6
  • 10
    • 0345486990 scopus 로고    scopus 로고
    • Noninvasive detection of cerebral hypoperfusion and reversible ischemia from reductions in the magnetic resonance imaging relaxation time, T2
    • Grohn OH, Lukkarinen JA, Oja JM, van Zijl PC, Ulatowski JA, Traystman RJ, et al. Noninvasive detection of cerebral hypoperfusion and reversible ischemia from reductions in the magnetic resonance imaging relaxation time, T2. J Cereb Blood Flow Metab. 1998;18:911-920.
    • (1998) J Cereb Blood Flow Metab , vol.18 , pp. 911-920
    • Grohn, O.H.1    Lukkarinen, J.A.2    Oja, J.M.3    Van Zijl, P.C.4    Ulatowski, J.A.5    Traystman, R.J.6
  • 11
    • 0028158554 scopus 로고
    • Intravascular susceptibility contrast mechanisms in tissues
    • Kennan RP, Zhong J, Gore JC. Intravascular susceptibility contrast mechanisms in tissues. Magn Reson Med. 1994;31:9-21.
    • (1994) Magn Reson Med , vol.31 , pp. 9-21
    • Kennan, R.P.1    Zhong, J.2    Gore, J.C.3
  • 12
    • 0028387214 scopus 로고
    • Spin-echo and gradient-echo EPI of human brain activation using bold contrast: A comparative study at 1.5 T
    • Bandettini PA, Wong EC, Jesmanowicz A, Hinks RS, Hyde JS. Spin-echo and gradient-echo EPI of human brain activation using bold contrast: a comparative study at 1.5 T. NMR Biomed. 1994;7:12-20.
    • (1994) NMR Biomed , vol.7 , pp. 12-20
    • Bandettini, P.A.1    Wong, E.C.2    Jesmanowicz, A.3    Hinks, R.S.4    Hyde, J.S.5
  • 13
    • 0033041270 scopus 로고    scopus 로고
    • Early changes in water diffusion, perfusion, T1, and T2 during focal cerebral ischemia in the rat studied at 8.5 T
    • Calamante F, Lythgoe MF, Pell GS, Thomas DL, King MD, Busza AL, et al. Early changes in water diffusion, perfusion, T1, and T2 during focal cerebral ischemia in the rat studied at 8.5 T. Magn Reson Med. 1999;41: 479-485.
    • (1999) Magn Reson Med , vol.41 , pp. 479-485
    • Calamante, F.1    Lythgoe, M.F.2    Pell, G.S.3    Thomas, D.L.4    King, M.D.5    Busza, A.L.6
  • 14
    • 0033964151 scopus 로고    scopus 로고
    • Graded reduction of cerebral blood flow in rat as detected by the nuclear magnetic resonance relaxation time T2: A theoretical and experimental approach
    • Grohn OH, Kettunen MI, Penttonen M, Oja JM, van Zijl PC, Kauppinen RA. Graded reduction of cerebral blood flow in rat as detected by the nuclear magnetic resonance relaxation time T2: a theoretical and experimental approach. J Cereb Blood Flow Metab. 2000;20:316-326.
    • (2000) J Cereb Blood Flow Metab , vol.20 , pp. 316-326
    • Grohn, O.H.1    Kettunen, M.I.2    Penttonen, M.3    Oja, J.M.4    Van Zijl, P.C.5    Kauppinen, R.A.6
  • 15
    • 0345425800 scopus 로고    scopus 로고
    • Quantitative magnetic resonance imaging assessment of cerebral ischemia in rat using on-resonance T(1) in the rotating frame
    • Grohn OH, Lukkarinen JA, Silvennoinen MJ, Pitkanen A, van Zijl PC, Kauppinen RA. Quantitative magnetic resonance imaging assessment of cerebral ischemia in rat using on-resonance T(1) in the rotating frame. Magn Reson Med. 1999;42:268-276.
    • (1999) Magn Reson Med , vol.42 , pp. 268-276
    • Grohn, O.H.1    Lukkarinen, J.A.2    Silvennoinen, M.J.3    Pitkanen, A.4    Van Zijl, P.C.5    Kauppinen, R.A.6
  • 17
    • 0028076303 scopus 로고
    • Changes in metabolites and tissue water status after focal ischemia in cat brain assessed with localized proton MR spectroscopy
    • van der Toorn A, Verheul HB, Berkelbach van der Sprenkel JW, Tulleken CA, Nicolay K. Changes in metabolites and tissue water status after focal ischemia in cat brain assessed with localized proton MR spectroscopy. Magn Reson Med. 1994;32:685-691.
    • (1994) Magn Reson Med , vol.32 , pp. 685-691
    • Van Der Toorn, A.1    Verheul, H.B.2    Berkelbach Van Der Sprenkel, J.W.3    Tulleken, C.A.4    Nicolay, K.5
  • 18
    • 0027937141 scopus 로고
    • Subcortical low intensity in early cortical ischemia
    • Ida M, Mizunuma K, Hata Y, Tada S. Subcortical low intensity in early cortical ischemia. AJNR Am J Neuroradiol. 1994;15:1387-1393.
    • (1994) AJNR Am J Neuroradiol , vol.15 , pp. 1387-1393
    • Ida, M.1    Mizunuma, K.2    Hata, Y.3    Tada, S.4
  • 20
    • 0029060916 scopus 로고
    • Identification of collaterally perfused areas following focal cerebral ischemia in the rat by comparison of gradient echo and diffusion-weighted MRI
    • Roussel SA, van Bruggen N, King MD, Gadian DG. Identification of collaterally perfused areas following focal cerebral ischemia in the rat by comparison of gradient echo and diffusion-weighted MRI. J Cereb Blood Flow Metab. 1995;15:578-586.
    • (1995) J Cereb Blood Flow Metab , vol.15 , pp. 578-586
    • Roussel, S.A.1    Van Bruggen, N.2    King, M.D.3    Gadian, D.G.4
  • 21
    • 0036213179 scopus 로고    scopus 로고
    • Detection of deoxygenation-related signal change in acute ischemic stroke patients by T2-weighted magnetic resonance imaging
    • Tamura H, Hatazawa J, Toyoshima H, Shimosegawa E, Okudera T. Detection of deoxygenation-related signal change in acute ischemic stroke patients by T2-weighted magnetic resonance imaging. Stroke. 2002;33:967-971.
    • (2002) Stroke , vol.33 , pp. 967-971
    • Tamura, H.1    Hatazawa, J.2    Toyoshima, H.3    Shimosegawa, E.4    Okudera, T.5
  • 22
    • 33750577188 scopus 로고    scopus 로고
    • Increased oxygen extraction demonstrated on gradient echo (T2*) imaging in a patient with acute ischaemic stroke
    • Wardlaw JM, von Heijne A. Increased oxygen extraction demonstrated on gradient echo (T2*) imaging in a patient with acute ischaemic stroke. Cerebrovasc Dis. 2006;22:456-458.
    • (2006) Cerebrovasc Dis , vol.22 , pp. 456-458
    • Wardlaw, J.M.1    Von Heijne, A.2
  • 27
    • 0031057902 scopus 로고    scopus 로고
    • Regional assessment of tissue oxygenation and the temporal evolution of hemodynamic parameters and water diffusion during acute focal ischemia in rat brain
    • Dijkhuizen RM, Berkelbach van der Sprenkel JW, Tulleken KA, Nicolay K. Regional assessment of tissue oxygenation and the temporal evolution of hemodynamic parameters and water diffusion during acute focal ischemia in rat brain. Brain Res. 1997;750:161-170.
    • (1997) Brain Res , vol.750 , pp. 161-170
    • Dijkhuizen, R.M.1    Berkelbach Van Der Sprenkel, J.W.2    Tulleken, K.A.3    Nicolay, K.4
  • 28
    • 0035719917 scopus 로고    scopus 로고
    • Cerebrovascular reactivity following focal brain ischemia in the rat: A functional magnetic resonance imaging study
    • Harris NG, Lythgoe MF, Thomas DL, Williams SR. Cerebrovascular reactivity following focal brain ischemia in the rat: a functional magnetic resonance imaging study. Neuroimage. 2001;13:339-350.
    • (2001) Neuroimage , vol.13 , pp. 339-350
    • Harris, N.G.1    Lythgoe, M.F.2    Thomas, D.L.3    Williams, S.R.4
  • 29
    • 0029879652 scopus 로고    scopus 로고
    • Cerebrovascular changes in rats during ischemia and reperfusion: A comparison of BOLD and first pass bolus tracking techniques
    • Jones RA, Muller TB, Haraldseth O, Baptista AM, Oksendal AN. Cerebrovascular changes in rats during ischemia and reperfusion: a comparison of BOLD and first pass bolus tracking techniques. Magn Reson Med. 1996;35:489-496.
    • (1996) Magn Reson Med , vol.35 , pp. 489-496
    • Jones, R.A.1    Muller, T.B.2    Haraldseth, O.3    Baptista, A.M.4    Oksendal, A.N.5
  • 30
    • 0033761709 scopus 로고    scopus 로고
    • Acute changes in MRI diffusion, perfusion, T(1), and T(2) in a rat model of oligemia produced by partial occlusion of the middle cerebral artery
    • Lythgoe MF, Thomas DL, Calamante F, Pell GS, King MD, Busza AL, et al. Acute changes in MRI diffusion, perfusion, T(1), and T(2) in a rat model of oligemia produced by partial occlusion of the middle cerebral artery. Magn Reson Med. 2000;44:706-712.
    • (2000) Magn Reson Med , vol.44 , pp. 706-712
    • Lythgoe, M.F.1    Thomas, D.L.2    Calamante, F.3    Pell, G.S.4    King, M.D.5    Busza, A.L.6
  • 31
    • 0030614588 scopus 로고    scopus 로고
    • T2-weighted magnetic resonance imaging of cerebrovascular reactivity in rat reversible focal cerebral ischemia
    • Ono Y, Morikawa S, Inubushi T, Shimizu H, Yoshimoto T. T2-weighted magnetic resonance imaging of cerebrovascular reactivity in rat reversible focal cerebral ischemia. Brain Res. 1997;744:207-215.
    • (1997) Brain Res , vol.744 , pp. 207-215
    • Ono, Y.1    Morikawa, S.2    Inubushi, T.3    Shimizu, H.4    Yoshimoto, T.5
  • 33
    • 79960978219 scopus 로고    scopus 로고
    • Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. Validation using 14C]2-deoxyglucose autoradiography
    • Robertson CA, McCabe C, Gallagher L, Lopez-Gonzalez Mdel R, Holmes WM, Condon B, et al. Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. Validation using [14C]2-deoxyglucose autoradiography. J Cereb Blood Flow Metab. 2011;31: 1778-1787.
    • (2011) J Cereb Blood Flow Metab , vol.31 , pp. 1778-1787
    • Robertson, C.A.1    McCabe, C.2    Gallagher, L.3    Lopez-Gonzalez Mdel, R.4    Holmes, W.M.5    Condon, B.6
  • 34
    • 52549121435 scopus 로고    scopus 로고
    • Potential use of oxygen as a metabolic biosensor in combination with T2-weighted MRI to define the ischemic penumbra
    • Santosh C, Brennan D, McCabe C, Macrae IM, Holmes WM, Graham DI, et al. Potential use of oxygen as a metabolic biosensor in combination with T2-weighted MRI to define the ischemic penumbra. J Cereb Blood Flow Metab. 2008;28:1742-1753.
    • (2008) J Cereb Blood Flow Metab , vol.28 , pp. 1742-1753
    • Santosh, C.1    Brennan, D.2    McCabe, C.3    MacRae, I.M.4    Holmes, W.M.5    Graham, D.I.6
  • 35
    • 81155134954 scopus 로고    scopus 로고
    • Probing ischemic tissue fate with bold fMRI of brief oxygen challenge
    • Shen Q, Huang S, Du F, Duong TQ. Probing ischemic tissue fate with bold fMRI of brief oxygen challenge. Brain Res. 2011;1425:132-141.
    • (2011) Brain Res , vol.1425 , pp. 132-141
    • Shen, Q.1    Huang, S.2    Du, F.3    Duong, T.Q.4
  • 36
    • 77954036216 scopus 로고    scopus 로고
    • T2-weighted magnetic resonance imaging with hyperoxia in acute ischemic stroke
    • Dani KA, Santosh C, Brennan D, McCabe C, Holmes WM, Condon B, et al. T2-weighted magnetic resonance imaging with hyperoxia in acute ischemic stroke. Ann Neurol. 2010;68:37-47.
    • (2010) Ann Neurol , vol.68 , pp. 37-47
    • Dani, K.A.1    Santosh, C.2    Brennan, D.3    McCabe, C.4    Holmes, W.M.5    Condon, B.6
  • 39
    • 59249108039 scopus 로고    scopus 로고
    • The correlation between quantitative T2-and regional cerebral blood flow after acute brain ischemia in early reperfusion as demonstrated in a middle cerebral artery occlusion/reperfusion model of the rat
    • Jensen UR, Liu JR, Eschenfelder C, Meyne J, Zhao Y, Deuschl G, et al. The correlation between quantitative T2-and regional cerebral blood flow after acute brain ischemia in early reperfusion as demonstrated in a middle cerebral artery occlusion/reperfusion model of the rat. J Neurosci Methods. 2009;178:55-58.
    • (2009) J Neurosci Methods , vol.178 , pp. 55-58
    • Jensen, U.R.1    Liu, J.R.2    Eschenfelder, C.3    Meyne, J.4    Zhao, Y.5    Deuschl, G.6
  • 40
    • 0032586035 scopus 로고    scopus 로고
    • Quantitative T*(2) and T-(2) maps during reversible focal cerebral ischemia in rats: Separation of blood oxygenation from nonsusceptibility-based contributions
    • Grune M, van Dorsten FA, Schwindt W, Olah L, Hoehn M. Quantitative T*(2) and T-(2) maps during reversible focal cerebral ischemia in rats: separation of blood oxygenation from nonsusceptibility-based contributions. Magn Reson Med. 1999;42:1027-1032.
    • (1999) Magn Reson Med , vol.42 , pp. 1027-1032
    • Grune, M.1    Van Dorsten, F.A.2    Schwindt, W.3    Olah, L.4    Hoehn, M.5
  • 41
    • 79953268448 scopus 로고    scopus 로고
    • Blood-oxygenation-level-dependent-(BOLD-) based R2-MRI study in monkey model of reversible middle cerebral artery occlusion
    • Zhang J, Chen YM, Zhang YT. Blood-oxygenation-level-dependent-(BOLD-) based R2-MRI study in monkey model of reversible middle cerebral artery occlusion. J Biomed Biotechnol. 2011;2011:318-346.
    • (2011) J Biomed Biotechnol , vol.2011 , pp. 318-346
    • Zhang, J.1    Chen, Y.M.2    Zhang, Y.T.3
  • 42
    • 33846911318 scopus 로고    scopus 로고
    • Visual rating of T2-blood-oxygen-level-dependent magnetic resonance imaging in acute stroke patients-A pilot study [in German
    • Fiehler J, Geisler B, Siemonsen S, Saager C, Speck O, Thomalla G, et al. Visual rating of T2-blood-oxygen-level-dependent magnetic resonance imaging in acute stroke patients-a pilot study [in German]. Rofo. 2007; 179:17-20.
    • (2007) Rofo , vol.179 , pp. 17-20
    • Fiehler, J.1    Geisler, B.2    Siemonsen, S.3    Saager, C.4    Speck, O.5    Thomalla, G.6
  • 43
    • 33745965541 scopus 로고    scopus 로고
    • Blood-oxygen-level-dependent MRI allows metabolic description of tissue at risk in acute stroke patients
    • Geisler BS, Brandhoff F, Fiehler J, Saager C, Speck O, Rother J, et al. Blood-oxygen-level-dependent MRI allows metabolic description of tissue at risk in acute stroke patients. Stroke. 2006;37:1778-1784.
    • (2006) Stroke , vol.37 , pp. 1778-1784
    • Geisler, B.S.1    Brandhoff, F.2    Fiehler, J.3    Saager, C.4    Speck, O.5    Rother, J.6
  • 44
    • 51549115731 scopus 로고    scopus 로고
    • T2-imaging predicts infarct growth beyond the acute diffusion-weighted imaging lesion in acute stroke
    • Siemonsen S, Fitting T, Thomalla G, Horn P, Finsterbusch J, Summers P, et al. T2-imaging predicts infarct growth beyond the acute diffusion-weighted imaging lesion in acute stroke. Radiology. 2008; 248:979-986.
    • (2008) Radiology , vol.248 , pp. 979-986
    • Siemonsen, S.1    Fitting, T.2    Thomalla, G.3    Horn, P.4    Finsterbusch, J.5    Summers, P.6
  • 45
    • 84859986093 scopus 로고    scopus 로고
    • Normal values of quantitative T2-in a spontaneously hypertensive stroke prone rat stem at 3 Tesla
    • Jensen-Kondering U, Bohm R, Höcker J, Ruhe R, Brdon J, Ulmer S. Normal values of quantitative T2-in a spontaneously hypertensive stroke prone rat stem at 3 Tesla. Eur J Radiol. 2011;81:985-987.
    • (2011) Eur J Radiol , vol.81 , pp. 985-987
    • Jensen-Kondering, U.1    Bohm, R.2    Höcker, J.3    Ruhe, R.4    Brdon, J.5    Ulmer, S.6
  • 46
    • 0035216720 scopus 로고    scopus 로고
    • Quantitative measurements of cerebral metabolic rate of oxygen utilization using MRI: A volunteer study
    • An H, Lin W, Celik A, Lee YZ. Quantitative measurements of cerebral metabolic rate of oxygen utilization using MRI: a volunteer study. NMR Biomed. 2001;14:441-447.
    • (2001) NMR Biomed , vol.14 , pp. 441-447
    • An, H.1    Lin, W.2    Celik, A.3    Lee, Y.Z.4
  • 47
    • 66849122074 scopus 로고    scopus 로고
    • Evaluation of MR-derived cerebral oxygen metabolic index in experimental hyperoxic hypercapnia, hypoxia, and ischemia
    • An H, Liu Q, Chen Y, Lin W. Evaluation of MR-derived cerebral oxygen metabolic index in experimental hyperoxic hypercapnia, hypoxia, and ischemia. Stroke. 2009;40:2165-2172.
    • (2009) Stroke , vol.40 , pp. 2165-2172
    • An, H.1    Liu, Q.2    Chen, Y.3    Lin, W.4
  • 48
    • 0037309222 scopus 로고    scopus 로고
    • Magnetic resonance cerebral metabolic rate of oxygen utilization in hyperacute stroke patients
    • Lee JM, Vo KD, An H, Celik A, Lee Y, Hsu CY, et al. Magnetic resonance cerebral metabolic rate of oxygen utilization in hyperacute stroke patients. Ann Neurol. 2003;53:227-232.
    • (2003) Ann Neurol , vol.53 , pp. 227-232
    • Lee, J.M.1    Vo, K.D.2    An, H.3    Celik, A.4    Lee, Y.5    Hsu, C.Y.6
  • 49
    • 67650034639 scopus 로고    scopus 로고
    • Negative fluid-attenuated inversion recovery imaging identifies acute ischemic stroke at 3 hours or less
    • Thomalla G, Rossbach P, Rosenkranz M, Siemonsen S, Krutzelmann A, Fiehler J, et al. Negative fluid-attenuated inversion recovery imaging identifies acute ischemic stroke at 3 hours or less. Ann Neurol. 2009;65: 724-732.
    • (2009) Ann Neurol , vol.65 , pp. 724-732
    • Thomalla, G.1    Rossbach, P.2    Rosenkranz, M.3    Siemonsen, S.4    Krutzelmann, A.5    Fiehler, J.6
  • 50
    • 0033056002 scopus 로고    scopus 로고
    • Selective cerebral hematocrit decrease in the centrum semiovale after carotid artery occlusion: A PET study
    • Yamauchi H, Fukuyama H, Nagahama Y, Katsumi Y, Hayashi T, Okazawa H, et al. Selective cerebral hematocrit decrease in the centrum semiovale after carotid artery occlusion: a PET study. J Cereb Blood Flow Metab. 1999;19:109-114.
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 109-114
    • Yamauchi, H.1    Fukuyama, H.2    Nagahama, Y.3    Katsumi, Y.4    Hayashi, T.5    Okazawa, H.6
  • 52
    • 0027973923 scopus 로고
    • Theory of NMR signal behavior in magnetically inhomogeneous tissues: The static dephasing regime
    • Yablonskiy DA, Haacke EM. Theory of NMR signal behavior in magnetically inhomogeneous tissues: the static dephasing regime. Magn Reson Med. 1994;32:749-763.
    • (1994) Magn Reson Med , vol.32 , pp. 749-763
    • Yablonskiy, D.A.1    Haacke, E.M.2
  • 53
    • 0018561023 scopus 로고
    • Analysis of oxygen diffusion from arteriolar networks
    • Popel AS, Gross JF. Analysis of oxygen diffusion from arteriolar networks. Am J Physiol. 1979;237:H681-689.
    • (1979) Am J Physiol , vol.237
    • Popel, A.S.1    Gross, J.F.2
  • 54
    • 0035217628 scopus 로고    scopus 로고
    • Assessment of brain tissue viability in acute ischemic stroke by BOLD MRI
    • Grohn OH, Kauppinen RA. Assessment of brain tissue viability in acute ischemic stroke by BOLD MRI. NMR Biomed. 2001;14:432-440.
    • (2001) NMR Biomed , vol.14 , pp. 432-440
    • Grohn, O.H.1    Kauppinen, R.A.2
  • 55
    • 34247596332 scopus 로고    scopus 로고
    • A review of oxygen therapy in ischemic stroke
    • Singhal AB. A review of oxygen therapy in ischemic stroke. Neurol Res. 2007;29:173-183.
    • (2007) Neurol Res , vol.29 , pp. 173-183
    • Singhal, A.B.1
  • 56
    • 2342656894 scopus 로고    scopus 로고
    • Outcome of acutely ischemic brain tissue in prolonged middle cerebral artery occlusion: A serial positron emission tomography investigation in the baboon
    • Giffard C, Young AR, Kerrouche N, Derlon JM, Baron JC. Outcome of acutely ischemic brain tissue in prolonged middle cerebral artery occlusion: a serial positron emission tomography investigation in the baboon. J Cereb Blood Flow Metab. 2004;24:495-508.
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 495-508
    • Giffard, C.1    Young, A.R.2    Kerrouche, N.3    Derlon, J.M.4    Baron, J.C.5
  • 57
    • 43549105600 scopus 로고    scopus 로고
    • PET O-15 cerebral blood flow and metabolism after acute stroke in spontaneously hypertensive rats
    • Temma T, Kuge Y, Sano K, Kamihashi J, Obokata N, Kawashima H, et al. PET O-15 cerebral blood flow and metabolism after acute stroke in spontaneously hypertensive rats. Brain Res. 2008;1212:18-24.
    • (2008) Brain Res , vol.1212 , pp. 18-24
    • Temma, T.1    Kuge, Y.2    Sano, K.3    Kamihashi, J.4    Obokata, N.5    Kawashima, H.6
  • 58
    • 44449099768 scopus 로고    scopus 로고
    • Applications of nitroimidazole in vivo hypoxia imaging in ischemic stroke
    • Takasawa M, Moustafa RR, Baron JC. Applications of nitroimidazole in vivo hypoxia imaging in ischemic stroke. Stroke. 2008;39: 1629-1637.
    • (2008) Stroke , vol.39 , pp. 1629-1637
    • Takasawa, M.1    Moustafa, R.R.2    Baron, J.C.3


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