Neonatal Fc receptor stimulation induces ubiquitin c-terminal hydrolase-1 overexpression in podocytes through activation of p38 mitogen-activated protein kinase

Human Pathology

Volumn 43, Issue 9, 2012, Pages 1482-1490

  Gan, Hualei ^a   Feng, Songtao ^a   Wu, Huijuan ^a   Sun, Yu ^a   Hu, Ruimin ^a   Zhao, Zhonghua ^a   Zhang, Zhigang ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Glomerulonephritides; Neonatal Fc receptor; p38; Podocyte; Ubiquitin c terminal hydrolase 1 (UCH L1)

Indexed keywords

FC RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE P38; THYMOCYTE ANTIBODY; UBIQUITIN C TERMINAL HYDROLASE 1; UBIQUITIN THIOLESTERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOIMMUNE DISEASE; CELL CULTURE; CONTROLLED STUDY; GENE OVEREXPRESSION; GLOMERULONEPHRITIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IMMUNOSTIMULATION; KIDNEY; KIDNEY DISEASE; LUPUS ERYTHEMATOSUS NEPHRITIS; MAJOR CLINICAL STUDY; MEMBRANOUS GLOMERULONEPHRITIS; MOUSE; NEWBORN; NONHUMAN; PODOCYTE; PROLIFERATIVE GLOMERULONEPHRITIS; PROTEIN EXPRESSION; RNA INTERFERENCE; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANTILYMPHOCYTE SERUM; CELL LINE; CELLS, CULTURED; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; KIDNEY; KIDNEY DISEASES; MICE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PODOCYTES; RECEPTORS, FC; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; UBIQUITIN THIOLESTERASE; UP-REGULATION;

EID: 84864282571     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2011.10.025     Document Type: Article

References (29)

1. S.J. Shankland The podocyte's response to injury: role in proteinuria and glomerulosclerosis Kidney Int 69 2006 2131 2147 (Pubitemid 43882099)
2. P. Mundel, and S.J. Shankland Podocyte biology and response to injury J Am Soc Nephrol 13 2002 3005 3015 (Pubitemid 35386921)
3. R.J. Coward, R.R. Foster, and D. Patton Nephrotic plasma alters slit diaphragm-dependent signaling and translocates nephrin, podocin, and CD2 associated protein in cultured human podocytes J Am Soc Nephrol 16 2005 629 637 (Pubitemid 41725099)
4. Y. Liu, J. Wu, and H. Wu UCH-L1 expression of podocytes in diseased glomeruli and in vitro J Pathol 217 2009 642 653
5. C. Meyer-Schwesinger, T.N. Meyer, and S. Münster A new role for the neuronal ubiquitin C-terminal hydrolase-L1 (UCH-L1) in podocyte process formation and podocyte injury in human glomerulopathies J Pathol 217 2009 452 464
6. K.D. Wilkinson, K.M. Lee, and S. Deshpande The neuron-specific protein PGP9.5 is a ubiquitin carboxyl-terminal hydrolase Science 246 1989 670 673 (Pubitemid 19283361)
7. A. Ciechanover, A. Orian, and A.L. Schwartz Ubiquitin-mediated proteolysis: biological regulation via destruction Bioessays 22 2000 442 451 (Pubitemid 30308270)
8. R. Layfield, J. Lowe, and L. Bedford The ubiquitin-proteasome system and neurodegenerative disorders Essays Biochem 41 2005 157 171 (Pubitemid 41500977)
9. Y. Liu, H.A. Lashuel, and S. Choi Discovery of inhibitors that elucidate the role of UCH-L1 activity in the H1299 lung cancer cell line Chem Biol 10 2003 837 846 (Pubitemid 37171901)
10. T. Yamazaki, K. Hibi, and T. Takase PGP 9.5 as a marker for invasive colorectal cancer Clin Cancer Res 8 2002 192 195 (Pubitemid 34101477)
11. H.J. Kim, Y.M. Kim, and S. Lim Ubiquitin C-terminal hydrolase-L1 is a key regulator of tumor cell invasion and metastasis Oncogene 28 2009 117 127
12. D.C. Roopenian, and S. Akilesh FcRn: the neonatal Fc receptor comes of age Nat Rev Immunol 7 2007 715 725 (Pubitemid 47327396)
13. J.L. Leach, D.D. Sedmak, and J.M. Osborne Isolation from human placenta of the IgG transporter, FcRn, and localization to the syncytiotrophoblast: implications for maternal-fetal antibody transport J Immunol 157 1996 3317 3322 (Pubitemid 126449142)
14. V. Ghetie, J.G. Hubbard, and J.K. Kim Abnormally short serum half-lives of IgG in β2-microglobulin-deficient mice Eur J Immunol 26 1996 690 696 (Pubitemid 26091401)
15. S. Akilesh, T.B. Huber, and H. Wu Podocytes use FcRn to clear IgG from the glomerular basement membrane Proc Natl Acad Sci U S A 105 2008 967 972 (Pubitemid 351282065)
16. R. Jia, X. Hong, S. Li, Y. Haichun, and H. Chuanming Expression of angiopoietin-like 3 associated with puromycin-induced podocyte damage Nephron Exp Nephrol 115 2010 38 45
17. G.P. Chen, M.Y. Guo, and Y.E. Zhang Preparation of anti-Thy1 serum and establishment of mesangioproliferative glomerulonephritis model in rat J Clin Exp Pathol 12 1996 241 243
18. A.J. Norton, S. Jordan, and P. Yemomans Brief, high temperature heat denaturation (pressure cooking): a simple and method of antigen retrieval for routinely processed tissue J Pathol 173 1994 371 379 (Pubitemid 24294106)
19. R. Mancilla-Jimenez, M. Appay, and B. Bellon IgG Fc membrane receptor on normal human glomerular visceral epithelial cells Virchows Arch A Pathol Anat Histopathol 404 1984 139 158 (Pubitemid 14028687)
20. Y. Mizoguchi, and Y. Horiuchi Localization of IgG-Fc receptors in human renal glomeruli Clin Immunol Immunopathol 24 1982 320 329 (Pubitemid 12057888)
21. J.P. Haymann, J.P. Levraud, and S. Bouet Characterization and localization of the neonatal Fc receptor in adult human kidney J Am Soc Nephrol 11 2000 632 639 (Pubitemid 30171872)
22. N. Tsuboi, K. Asano, M. Lauterbach, and T.N. Mayadas Human neutrophil Fcgamma receptors initiate and play specialized nonredundant roles in antibody-mediated inflammatory diseases Immunity 28 2008 833 846
23. D.C. Roopenian, G.J. Christianson, and T.J. Sproule The MHC class I-like IgG receptor controls perinatal IgG transport, IgG homeostasis, and fate of IgE-Fc-coupled drugs J Immunol 170 2003 3528 3533 (Pubitemid 36359219)
24. N.E. Simister, and K.E. Mostov An Fc receptor structurally related to MHC class I antigens Nature 337 1989 184 187 (Pubitemid 19025381)
25. K.M. McCarthy, Y. Yoong, and N.E. Simister Bidirectional transcytosis of IgG by the rat neonatal Fc receptor expressed in a rat kidney cell line: a system to study protein transport across epithelia J Cell Sci 113 2000 1277 1285 (Pubitemid 30229544)
26. S.L. Verdin-Terán, A. Vilches-Flores, and L. Moreno-Fierros Immunization with Cry1Ac from Bacillus thuringiensis increases intestinal IgG response and induces the expression of FcRn in the intestinal epithelium of adult mice Scand J Immunol 70 2009 596 607
27. L. Aoudjit, M. Stanciu, H. Li, S. Lemay, and T. Takano p38 mitogen-activated protein kinase protects glomerular epithelial cells from complement-mediated cell injury Am J Physiol Renal Physiol 285 2003 765 774
28. L. Adhikary, F. Chow, and D.J. Nikolic-Paterson Abnormal p38 mitogen-activated protein kinase signalling in human and experimental diabetic nephropathy Diabetologia 47 2004 1210 1222 (Pubitemid 39093317)
29. M. Koshikawa, M. Mukoyama, and K. Mori Role of p38 mitogen-activated protein kinase activation in podocyte injury and proteinuria in experimental nephrotic syndrome J Am Soc Nephrol 16 2005 2690 2701