High pesticide exposure events and central nervous system function among pesticide applicators in the Agricultural Health Study

International Archives of Occupational and Environmental Health

Volumn 85, Issue 5, 2012, Pages 505-515

  Starks, Sarah E ^a   Gerr, Fred ^a   Kamel, Freya ^b   Lynch, Charles F ^a   Alavanja, Michael C ^c   Sandler, Dale P ^b   Hoppin, Jane A ^b  

^a UNIVERSITY OF IOWA   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Agricultural workers; Epidemiology; High pesticide exposure event; Neurobehavioral testing; Pesticide exposure

Indexed keywords

PESTICIDE;

AGED; AGRICULTURE; ARTICLE; CENTRAL NERVOUS SYSTEM; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; HUMAN; MALE; MIDDLE AGED; OCCUPATIONAL DISEASE; OCCUPATIONAL EXPOSURE; PROSPECTIVE STUDY; QUESTIONNAIRE; STATISTICAL MODEL; UNITED STATES;

AGED; AGED, 80 AND OVER; AGRICULTURE; CENTRAL NERVOUS SYSTEM; HUMANS; IOWA; LINEAR MODELS; MALE; MIDDLE AGED; NORTH CAROLINA; OCCUPATIONAL DISEASES; OCCUPATIONAL EXPOSURE; PESTICIDES; PROSPECTIVE STUDIES; QUESTIONNAIRES;

EID: 84864278139     PISSN: 03400131     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00420-011-0694-8     Document Type: Article

References (57)

1. AHS (2010) Full text of questionnaires. Available: http://www. aghealth.nci.nih.gov/questionnaires.html
2. Alavanja MC, Sandler DP, McMaster SB et al (1996) The Agricultural Health Study. Environ Health Perspect 104(4):362-369 (Pubitemid 26160821)
3. Alavanja MC, Sandler DP, McDonnell CJ et al (1999) Characteristics of persons who self-reported a high pesticide exposure event in the Agricultural Health Study. Environ Res 80(2 Pt 1):180-186
4. Ames RG, Steenland K, Jenkins B et al (1995) Chronic neurologic sequelae to cholinesterase inhibition among agricultural pesticide applicators. Arch Environ Health 50(6):440-444 (Pubitemid 26013361)
5. Anger WK (2003) Neurobehavioural tests and systems to assess neurotoxic exposures in the workplace and community. Occup Environ Med 60(7): 531-538, 474
6. Anger WK, Moody L, Burg JE et al (1986) Neurobehavioral evaluation of soil and structural fumigators using methyl bromide and sulfuryl fluoride. NeuroToxicology. 7(3):137-156 (Pubitemid 17215731)
7. Baldi I, Filleul L, Mohammed-Brahim B et al (2001) Neuropsychologic Effects of Long-Term Exposure to Pesticides: Results from the French Phytoner Study. Environ Health Perspect 109:839-844 (Pubitemid 32910308)
8. Bardin PG, van Eeden SF, Moolman JA et al (1994) Organophosphate and carbamate poisoning. Arch Intern Med 154(13):1433-1441 (Pubitemid 24208568)
9. Bazylewicz-Walczak B, Majczakowa W, Szymczak M (1999) Behavioral effects of occupational exposure to organophosphorous pesticides in female greenhouse planting workers. Neurotoxicology 20(5):819-826
10. Bell EM, Sandler DP, Alavanja MC (2006) High pesticide exposure events among farmers and spouses enrolled in the Agricultural Health Study. J Agric Saf Health 12(2):101-116 (Pubitemid 43676153)
11. Bradberry SM, Proudfoot AT, Vale JA et al (2004) Poisoning due to chlorophenoxy herbicides. Toxicology Review. 23:65-73 (Pubitemid 40674224)
12. Bradberry SM, Cage SA, Proudfoot AT, Vale JA (2005) Poisoning due to pyrethroids. Toxicology Review. 24:93-106 (Pubitemid 41455880)
13. Colosio C, Tiramani M, Brambilla G, Colombi A, Moretto A (2009) Neurobehavioral effects of pesticides with special focus on organophosphorus compounds: Which is the real size of the problem? NeuroToxicology 30:1155-1161
14. Costa LG (2006) Current issues in organophosphate toxicology. Clin Chim Acta 366(1-2):1-13 (Pubitemid 43330962)
15. Costa LG, Giordano G, Guizzetti M et al (2008) Neurotoxicity of pesticides: a brief review. Front Biosci 13:1240-1249 (Pubitemid 351594708)
16. Cox C, Surgan M (2006) Unidentified inert ingredients in pesticides: implications for human and environmental health. Environ Health Perspect 114(12):1803-1806 (Pubitemid 44873676)
17. Daniell W, Barnhart S, Demers P et al (1992) Neuropsychological performance among agricultural pesticide applicators. Environ Res 59(1):217-228
18. EPA (2003) Promoting Safety for America's Future: Office of Pesticide Programs FY 2002 Annual Report:2003. Washington, DC
19. EPA (2011a) Pesticides industry sales and usage: 2006 and 2007 market estimates Washington
20. EPA (2011b) What is a pesticide? Available: http://www.epa.gov/ pesticides/about/index.htm [accessed April 13, 2011]
21. Farahat TM, Abdelrasoul GM, Amr MM et al (2003) Neurobehavioral effects among workers occupationally exposed to organophosphate pesticides. Occup Environ Med 60:279-286 (Pubitemid 36408252)
22. Fiedler N, Kipen H, Kelly-McNeil K et al (1997) Long-term use of organophosphates and neuropsychological performance. Am J Ind Med 32(5):487-496 (Pubitemid 27419250)
23. Greenwood MR (1985) Methylmercury poisoning in Iraq. An epidemiological study of the 1971-1972 outbreak. J. Appl Toxicol 5(3):148-159 (Pubitemid 15065117)
24. Kamel F, Hoppin JA (2004) Association of pesticide exposure with neurologic dysfunction and disease. Environ Health Perspect 112:950-958 (Pubitemid 38931102)
25. Kamel F, Rowland AS, Park LP et al (2003) Neurobehavioral performance and work experience in Florida farmworkers. Environ Health Perspect 111(14):1765-1772 (Pubitemid 37407938)
26. Keifer MC, Firestone J (2007) Neurotoxicity of pesticides. Journal of agromedicine 12(1):17-25 (Pubitemid 47371741)
27. Keim SA, Alavanja MC (2001) Pesticide use by persons who reported a high pesticide exposure event in the Agricultural Health Study. Environ Res 85(3):256-259 (Pubitemid 32225344)
28. Kleinbaum DG (1998) Applied regression analysis and other multivariable methods, 3rd ed edn. Duxbury Press, Pacific Grove
29. Klove H (1963) Clinical Neuropsychology. Med Clin North Am 47:1647-1658
30. Letz R (2000) NES3 User's Manual. Neurobehavioral Systems Inc, Atlanta, GA
31. Letz R, Green RC, Woodard JL (1996) Development of a computerbased battery designed to screen adults for neuropsychological impairment. Neurotoxicol Teratol 18(4):365-370 (Pubitemid 26288701)
32. Letz R, Gerr F, Cragle D et al (2000) Residual neurologic deficits 30 years after occupational exposure to elemental mercury. Neurotoxicology 21(4):459-474
33. Letz R, DiIorio CK, Shafer PO et al (2003a) Further Standardization of Some NES3 Tests. NeuroToxicology 24(4-5):491-501 (Pubitemid 36994220)
34. Letz R, DiIorio CK, Shafer PO et al (2003b) A Computer-based Reading Test for Use as an Index of Premorbid General Intellectual Level in North American English-speaking Adults. NeuroToxicology 24(4-5):503-512 (Pubitemid 36994221)
35. London L, Nell V, Thompson ML et al (1998) Effects of long-term organophosphate exposures on neurological symptoms, vibration sense and tremor among South African farm workers. Scand J Work Environ Health 24(1):18-29 (Pubitemid 28156013)
36. Mackenzie Ross SJ, Brewin CR, Curran HV et al (2010) Neuropsychological and psychiatric functioning in sheep farmers exposed to low levels of organophosphate pesticides. Neurotoxicol Teratol 32:452-459
37. Marrs TC (1993) Organophosphate poisoning. Pharmacol Ther 58(1):51-66 (Pubitemid 23227698)
38. O'Malley MA, Fong H, Mehler L et al (2011) Illness Associated with Exposure to Methyl Bromide-Fumigated Produce - California, 2010. MMWR 60:923-926
39. Pilkington A, Buchanan D, Jamal GA et al (2001) An epidemiological study of the relations between exposure to organophosphate pesticides and indices of chronic peripheral neuropathy and neuropsychological abnormalities in sheep farmers and dippers. Occup Environ Med 58:702-710 (Pubitemid 33010487)
40. Ray DE, Fry FR (2006) A reassessment of the neurotoxicity of pyrethroid insecticides. Pharmacol Ther 111:174-193 (Pubitemid 44226293)
41. Ray DE, Richards PG (2001) The potential for toxic effects of chronic, low-dose exposure to organophosphates. Toxicol Lett 120(1-3):343-351 (Pubitemid 32375101)
42. Reuber MD (1983) Carcinogenicity and toxicity of 2, 4-dichlorophenoxy- acetic acid. Sci Total Environ 31(3):203-218 (Pubitemid 14182252)
43. Rohlman DS, Lasarev M, Anger WK et al (2007) Neurobehavioral performance of adult and adolescent agricultural workers. Neurotoxicology 28(2):374-380 (Pubitemid 46850762)
44. Rohlman DS, Anger KW, Lein PJ (2011) Correlating neurobehavioral performance with biomarkers of organophosphorus pesticide exposure. NeuroToxicology. 32:268-276
45. Roldan-Tapia L, Parron T, Sanchez-Santed F (2005) Neuropsychological effects of long-term exposure to organophosphate pesticides. Neurotoxicol Teratol 27(2):259-266 (Pubitemid 40279135)
46. Rosenstock L, Keifer M, Daniell WE et al (1991) Chronic central nervous system effects of acute organophosphate pesticide intoxication. The Pesticide Health Effects Study Group. Lancet 338(8761):223-227
47. Rothlein J, Rohlman D, Lasarev M et al (2006) Organophosphate pesticide exposure and neurobehavioral performance in agricultural and non-agricultural Hispanic workers. Environ Health Perspect 114:691-696
48. Singer R, Moses M, Valciukas J (1982) Nerve conduction velocity studies of workers employed in the manufacture of phenoxy herbicides. Environ Res 29(2):297-311 (Pubitemid 13155417)
49. Stallones L, Beseler C (2002) Pesticide poisoning and depressive symptoms among farm residents. Ann Epidemiol 12(6):389-394 (Pubitemid 34823637)
50. Steenland K, Jenkins B, Ames RG et al (1994) Chronic neurological sequelae to organophosphate pesticide poisoning. Am J Public Health 84(5):731-736 (Pubitemid 24237348)
51. Steenland K, Dick RB, Howell RJ et al (2000) Neurologic function among termiticide applicators exposed to chlorpyrifos. Environ Health Perspect 108(4):293-300 (Pubitemid 30251831)
52. van Wendel de Joode B, Wesseling C, Kromhout H et al (2001) Chronic nervous system effects of long-term occupational exposure to DDT. Lancet 357:1014-1016 (Pubitemid 32285398)
53. Vijverberg HPM, van den Bercken J (1990) Neurotoxicological effects and the mode of action of pyrethroid insecticides. Crit Rev Toxicology 21(2):105-126
54. Watson D, Clark LA, Tellegen A (1988) Development and validation of brief measures of positive and negative affect: the PANAS scales. J Pers Soc Psychol 54(6):1063-1070
55. Wechsler D (1981) Wechsler adult intelligence scale-revised. The Psychological Corporation, San Antonio
56. Weinhold B (2010) Mystery in a bottle: will the EPA require public disclosure of inert pesticide ingredients? Environ Health Perspect 118(4):A168-A171
57. Wesseling C, Keifer M, Ahlbom A et al (2002) Long-term neurobehavioral effects of mild poisonings with organophosphate and n-methyl carbamate pesticides among banana workers. Int J Occup Environ Health 8(1):27-34 (Pubitemid 34150630)