Role of cyclin D1 amplification and expression in vulvar carcinomas

Human Pathology

Volumn 43, Issue 9, 2012, Pages 1386-1393

  Choschzick, Matthias ^a   Hess, Stephan ^a   Tennstedt, Pierre ^a   Holst, Frederik ^a   Bohlken, Hiltila ^a   Gieseking, Frederike ^a   Mahner, Sven ^a   Woelber, Linn ^a   Simon, Ronald ^a   Sauter, Guido ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Amplification; CCND1; HPV; Vulvar cancer

Indexed keywords

CYCLIN D1;

ADULT; AGED; ARTICLE; CANCER PROGNOSIS; COPY NUMBER VARIATION; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; TISSUE MICROARRAY; VULVA CARCINOMA;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA; CYCLIN D1; FEMALE; GENE AMPLIFICATION; HUMANS; LYMPHATIC METASTASIS; MIDDLE AGED; PROGNOSIS; TUMOR MARKERS, BIOLOGICAL; VULVA; VULVAR NEOPLASMS;

EID: 84864277049     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2011.11.014     Document Type: Article

References (37)

1. S. Myllykangas, T. Bohling, and S. Knuutila Specificity, selection and significance of gene amplifications in cancer Semin Cancer Biol 17 2007 42 55 (Pubitemid 46075192)
2. D.G. Allen, A.M. Hutchins, and F. Hammet Genetic aberrations detected by comparative genomic hybridisation in vulvar cancers Br J Cancer 86 2002 924 928 (Pubitemid 34271029)
3. S. Aulmann, J. Schleibaum, R. Penzel, P. Schirmacher, G. Gebauer, and H.P. Sinn Gains of chromosome region 3q26 in intraepithelial neoplasia and invasive squamous cell carcinoma of the vulva are frequent and independent of HPV status J Clin Pathol 61 2008 1034 1037
4. K.J. Jee, Y.T. Kim, K.R. Kim, H.S. Kim, A. Yan, and S. Knuutila Loss in 3p and 4p and gain of 3q are concomitant aberrations in squamous cell carcinoma of the vulva Mod Pathol 14 2001 377 381 (Pubitemid 32448733)
5. F.Y. Huang, Y.K. Kwok, E.T. Lau, M.H. Tang, T.Y. Ng, and H.Y. Ngan Genetic abnormalities and HPV status in cervical and vulvar squamous cell carcinomas Cancer Genet Cytogenet 157 2005 42 48 (Pubitemid 40164857)
6. O. Yangling, Z. Shulang, C. Rongli, L. Bo, C. Lili, and W. Xin Genetic imbalance and human papillomavirus states in vulvar squamous cell carcinomas Eur J Gynaecol Oncol 28 2007 442 446
7. W.B. Growdon, S.L. Boisvert, and S. Akhavanfard Decreased survival in EGFR gene amplified vulvar carcinoma Gynecol Oncol 111 2008 289 297
8. R. Kurzrock, S. Ku, and M. Talpaz Abnormalities in the PRAD1 (CYCLIN D1/BCL-1) oncogene are frequent in cervical and vulvar squamous cell carcinoma cell lines Cancer 75 1995 584 590
9. J.P. Kunjoonju, M. Raitanen, S. Grenman, N. Tiwari, and M.J. Worsham Identification of individual genes altered in squamous cell carcinoma of the vulva Genes Chromosomes Cancer 44 2005 185 193 (Pubitemid 41306647)
10. T. Motokura, T. Bloom, and H.G. Kim A novel cyclin encoded by a bcl1-linked candidate oncogene Nature 350 1991 512 515 (Pubitemid 21912266)
11. M. Fu, C. Wang, Z. Li, T. Sakamaki, and R.G. Pestell Minireview: cyclin D1: normal and abnormal functions Endocrinology 145 2004 5439 5447 (Pubitemid 39564581)
12. Y. Xiong, T. Connolly, B. Futcher, and D. Beach Human D-type cyclin Cell 65 1991 691 699
13. E.A. Musgrove, C.S. Lee, M.F. Buckley, and R.L. Sutherland Cyclin D1 induction in breast cancer cells shortens G1 and is sufficient for cells arrested in G1 to complete the cell cycle Proc Natl Acad Sci U S A 91 1994 8022 8026 (Pubitemid 24253878)
14. J. Lukas, H. Muller, and J. Bartkova DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in G1 J Cell Biol 125 1994 625 638 (Pubitemid 24149844)
15. H. Muller, J. Lukas, and A. Schneider Cyclin D1 expression is regulated by the retinoblastoma protein Proc Natl Acad Sci U S A 91 1994 2945 2949 (Pubitemid 24130151)
16. Z. Li, C. Wang, G.C. Prendergast, and R.G. Pestell Cyclin D1 functions in cell migration Cell Cycle 5 2006 2440 2442 (Pubitemid 44785818)
17. W. Jiang, S.M. Kahn, N. Tomita, Y.J. Zhang, S.H. Lu, and I.B. Weinstein Amplification and expression of the human cyclin D gene in esophageal cancer Cancer Res 52 1992 2980 2983
18. C. Gillett, V. Fantl, and R. Smith Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining Cancer Res 54 1994 1812 1817 (Pubitemid 24116192)
19. D.C. Betticher, J. Heighway, and P.S. Hasleton Prognostic significance of CCND1 (cyclin D1) overexpression in primary resected non-small-cell lung cancer Br J Cancer 73 1996 294 300 (Pubitemid 26047506)
20. R. Simon, M. Mirlacher, and G. Sauter Tissue microarrays Biotechniques 36 2004 98 105 (Pubitemid 38076386)
21. I. Petersen, C. Schewe, and K. Schluns Inter-laboratory validation of PCR-based HPV detection in pathology specimens Virchows Arch 451 2007 701 716 (Pubitemid 47340979)
22. E. Lerma, M. Esteller, J.G. Herman, and J. Prat Alterations of the p16/Rb/cyclin-D1 pathway in vulvar carcinoma, vulvar intraepithelial neoplasia, and lichen sclerosus Hum Pathol 33 2002 1120 1125 (Pubitemid 35416710)
23. K.J. Rolfe, J.C. Crow, E. Benjamin, W.M. Reid, A.B. Maclean, and C.W. Perrett Cyclin D1 and retinoblastoma protein in vulvar cancer and adjacent lesions Int J Gynecol Cancer 11 2001 381 386 (Pubitemid 33021140)
24. S. Rocha, A.M. Martin, D.W. Meek, and Perkins ND p53 represses cyclin D1 transcription through down regulation of Bcl-3 and inducing increased association of the p52 NF-kappaB subunit with histone deacetylase 1 Mol Cell Biol 23 2003 4713 4727 (Pubitemid 36740458)
25. J. Lukas, J. Bartkova, and J. Bartek Convergence of mitogenic signalling cascades from diverse classes of receptors at the cyclin D-cyclin-dependent kinase-pRb-controlled G1 checkpoint Mol Cell Biol 16 1996 6917 6925 (Pubitemid 26389751)
26. Y.Y. Lee, S.P. Wilczynski, A. Chumakov, D. Chih, and H.P. Koeffler Carcinoma of the vulva: HPV and p53 mutations Oncogene 9 1994 1655 1659 (Pubitemid 24163392)
27. S. Narumiya, M. Tanji, and T. Ishizaki Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion Cancer Metastasis Rev 28 2009 65 76
28. S. Pellegrin, and H. Mellor Actin stress fibres J Cell Sci 120 2007 3491 3499
29. R.M. Fernandez, M. Ruiz-Miro, X. Dolcet, M. Aldea, and E. Gari Cyclin D1 interacts and collaborates with Ral GTPases enhancing cell detachment and motility Oncogene 30 2011 1936 1946
30. Z. Li, C. Wang, and X. Jiao Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1 and ROCK signaling Mol Cell Biol 26 2006 4240 4256 (Pubitemid 43788023)
31. I.A. van der Avoort, H. Shirango, and B.M. Hoevenaars Vulvar squamous cell carcinoma is a multifactorial disease following two separate and independent pathways Int J Gynecol Pathol 25 2006 22 29 (Pubitemid 44638331)
32. J.S. Smith, D.M. Backes, B.E. Hoots, R.J. Kurman, and J.M. Pimenta Human papillomavirus type-distribution in vulvar and vaginal cancers and their associated precursors Obstet Gynecol 113 2009 917 924
33. T. Toki, R.J. Kurman, J.S. Park, T. Kessis, R.W. Daniel, and K.V. Shah Probable nonpapillomavirus etiology of squamous cell carcinoma of the vulva in older women: a clinicopathologic study using in situ hybridization and polymerase chain reaction Int J Gynecol Pathol 10 1991 107 125
34. R.J. Kurman, T. Toki, and M.H. Schiffman Basaloid and warty carcinomas of the vulva. Distinctive types of squamous cell carcinoma frequently associated with human papillomaviruses Am J Surg Pathol 17 1993 133 145 (Pubitemid 23044878)
35. A.P. Pinto, L.B. Signorello, C.P. Crum, B.L. Harlow, F. Abrao, and L.L. Villa Squamous cell carcinoma of the vulva in Brazil: prognostic importance of host and viral variables Gynecol Oncol 74 1999 61 67 (Pubitemid 29331168)
36. A. Sedlis, H. Homesley, and B.N. Bundy Positive groin lymph nodes in superficial squamous cell vulvar cancer. A Gynecologic Oncology Group Study Am J Obstet Gynecol 156 1987 1159 1164 (Pubitemid 17075468)
37. L. Woelber, S. Mahner, and K. Voelker Clinicopathological prognostic factors and patterns of recurrence in vulvar cancer Anticancer Res 29 2009 545 552