High-resolution 3-dimensional reconstruction of the infarct border zone: Impact of structural remodeling on electrical activation

Circulation Research

Volumn 111, Issue 3, 2012, Pages 301-311

  Rutherford, Sally L ^a   Trew, Mark L ^a   Sands, Gregory B ^a   Legrice, Ian J ^a   Smaill, Bruce H ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CELL VIABILITY; COMPUTER MODEL; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CORONARY ARTERY LIGATION; ENDOCARDIUM; EPICARDIUM; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE; HEART MUSCLE CELL; HEART MUSCLE CONDUCTION DISTURBANCE; HEART VENTRICLE INFARCTION; MALE; MUSCLE FIBER MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REENTRY ARRHYTHMIA; SIMULATION; THREE DIMENSIONAL IMAGING;

ANIMALS; HEART CONDUCTION SYSTEM; IMAGING, THREE-DIMENSIONAL; MALE; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; RATS; VENTRICULAR REMODELING;

EID: 84864266812     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.111.260943     Document Type: Article

References (36)

1. Myerburg RJ, Castellanos A. Cardiac arrest and sudden death. In: Libby P, Bonow RO, Mann DL, Zipes DP, eds. Braunwaldâs Heart Disease. 8th ed. Philadelphia, PA: Sauders Elsevier; 2008:933-974.
2. de Bakker JM, van Capelle FJ, Janse MJ, Wilde AA, Coronel R, Becker AE, Dingemans KP, van Hemel NM, Hauer RN. Reentry as a cause of ventricular tachycardia in patients with chronic ischemic heart disease: electrophysiologic and anatomic correlation. Circulation. 1988;77: 589-606. (Pubitemid 18073351)
3. de Bakker JMT, Vancapelle FJL, Janse MJ, Tasseron S, Vermeulen JT, Dejonge N, Lahpor JR. Slow conduction in the infarcted human heart- zigzag course of activation. Circulation. 1993;88:915-926. (Pubitemid 23264006)
4. Luke RA, Saffitz JE. Remodeling of ventricular conduction pathways in healed canine infarct border zones. J Clin Invest. 1991;87:1594-1602.
5. Peters NS, Coromilas J, Severs NJ, Wit AL. Disturbed connexin43 gap junction distribution correlates with the location of reentrant circuits in the epicardial border zone of healing canine infarcts that cause ventricular tachycardia. Circulation. 1997;95:988.
6. Dun W, Baba S, Yagi T, Boyden PA. Dynamic remodeling of K+ and Ca2+ currents in cells that survived in the epicardial border zone of canine healed infarcted heart. Am J Physiol: Heart C. 2004;287: H1046-H1054. (Pubitemid 39096649)
7. Pu J, Boyden PA. Alterations of Na+ currents in myocytes from epicardial border zone of the infarcted heart. A possible ionic mechanism for reduced excitability and postrepolarization refractoriness. Circ Res. 1997; 81:110-119. (Pubitemid 27272989)
8. Sosnovik DE, Wang R, Dai G, Wang T, Aikawa E, Novikov M, Rosenzweig A, Gilbert RJ, Wedeen VJ. Diffusion spectrum MRI tractography reveals the presence of a complex network of residual myofibers in infarcted myocardium. Circ Cardiovasc Imaging. 2009; 2:206-212.
9. Yan AT, Shayne AJ, Brown KA, Gupta SN, Chan CW, Luu TM, Di Carli MF, Reynolds HG, Stevenson WG, Kwong RY. Characterization of the peri-infarct zone by contrast-enhanced cardiac magnetic resonance imaging is a powerful predictor of post-myocardial infarction mortality. Circulation. 2006;114:32-39. (Pubitemid 44305272)
10. Ashikaga H, Sasano T, Dong J, et al. Magnetic resonance-based anatomical analysis of scar-related ventricular tachycardia: implications for catheter ablation. Circ Res. 2007;101:939-947. (Pubitemid 350287181)
11. Sivagangabalan G, Pouliopoulos J, Huang K, Lu J, Barry MA, Thiagalingam A, Ross DL, Thomas SP, Kovoor P. Comparison of electroanatomic contact and noncontact mapping of ventricular scar in a postinfarct ovine model with intramural needle electrode recording and histological validation. Circ Arrhythm Electrophysiol. 2008;1: 363-369.
12. Mills WR, Mal N, Forudi F, Popovic ZB, Penn MS, Laurita KR. Optical mapping of late myocardial infarction in rats. Am J Physiol: Heart C. 2006;290:H1298-H1306.
13. Caldwell BJ, Trew ML, Sands GB, Hooks DA, LeGrice IJ, Smaill BH. Three distinct directions of intramural activation reveal nonuniform sideto- side electrical coupling of ventricular myocytes. Circ Arrhythm Electrophysiol. 2009;2:433-440.
14. Vigmond E, Vadakkumpadan F, Gurev V, Arevalo H, Deo M, Plank G, Trayanova N. Towards predictive modelling of the electrophysiology of the heart. Exp Physiol. 2009;94:563-577.
15. Spach MS, Heidlage JF, Dolber PC, Barr RC. Mechanism of origin of conduction disturbances in aging human atrial bundles: experimental and model study. Heart Rhythm. 2007;4:175-185. (Pubitemid 46158701)
16. Engelman ZJ, Trew ML, Smaill BH. Structural heterogeneity alone is a sufficient substrate for dynamic instability and altered restitution. Circ Arrhythm Electrophysiol. 2010;3:195-203.
17. Ciaccio EJ, Ashikaga H, Kaba RA, Cervantes D, Hopenfeld B, Wit AL, Peters NS, McVeigh ER, Garan H, Coromilas J. Model of reentrant ventricular tachycardia based upon infarct border zone geometry predicts reentrant circuit features as determined by activation mapping. Heart Rhythm. 2007;4:1034-1045. (Pubitemid 47163741)
18. Sands GB, Gerneke DA, Hooks DA, Green CR, Smaill BH, LeGrice IJ. Automated imaging of extended tissue volumes using confocal microscopy. Microsc Res Techniq. 2005;67:227-239. (Pubitemid 41400783)
19. Luo CH, Rudy Y. A model of the ventricular cardiac action potential. Depolarization, repolarization, and their interaction. Circ Res. 1991;68: 1501-1526.
20. Kimura S, Bassett AL, Kohya T, Kozlovskis PL, Myerburg RJ. Automaticity, triggered activity, and responses to adrenergic stimulation in cat subendocardial purkinje fibers after healing of myocardial infarction. Circulation. 1987;75:651-660. (Pubitemid 17026058)
21. Denniss AR, Richards DA, Waywood JA, Yung T, Kam CA, Ross DL, Uther JB. Electrophysiological and anatomic differences between canine hearts with inducible ventricular tachycardia and fibrillation associated with chronic myocardial infarction. Circ Res. 1989;64: 155-166. (Pubitemid 19028514)
22. Smith JH, Green CR, Peters NS, Rothery S, Severs NJ. Altered patterns of gap junction distribution in ischemic heart disease. An immunohistochemical study of human myocardium using laser scanning confocal microscopy. Am J Pathol. 1991;139:801-821.
23. LeGrice IJ, Smaill BH, Chai LZ, Edgar SG, Gavin JB, Hunter PJ. Laminar structure of the heart: ventricular myocyte arrangement and connective tissue architecture in the dog. Am J Physiol: Heart Circ Physiol. 1995;269:H571-H582.
24. Pope AJ, Sands GB, Smaill BH, LeGrice IJ. Three-dimensional transmural organization of perimysial collagen in the heart. Am J Physiol: Heart C. 2008;295:H1243-H1252.
25. Kucera JP, Kleber AG, Rohr S. Slow conduction in cardiac tissue: II. Effects of branching tissue geometry. Circ Res. 1998;83:795-805. (Pubitemid 28489076)
26. Fast VG, Kleber AG. Cardiac tissue geometry as a determinant of unidirectional conduction block: assessment of microscopic excitation spread by optical mapping in patterned cell cultures and in a computer model. Cardiovasc Res. 1995;29:697-707.
27. Cabo C, Pertsov AM, Davidenko JM, Baxter WT, Gray RA, Jalife J. Vortex shedding as a precursor of turbulent electrical activity in cardiac muscle. Biophys J. 1996;70:1105-1111. (Pubitemid 26073027)
28. Yao JA, Jiang M, Fan JS, Zhou YY, Tseng GN. Heterogeneous changes in K currents in rat ventricles three days after myocardial infarction. Cardiovasc Res. 1999;44:132-145. (Pubitemid 29431691)
29. Decker KF, Rudy Y. Ionic mechanisms of electrophysiological heterogeneity and conduction block in the infarct border zone. Am J Physiol: Heart Circ Physiol. 2010;299:H1588-1597.
30. Myerburg RJ, Gelband H, Nilsson K, Sung RJ, Thurer RJ, Morales AR, Bassett AL. Long-term electrophysiological abnormalities resulting from experimental myocardial infarction in cats. Circ Res. 1977;41:73-84. (Pubitemid 8132087)
31. Ursell PC, Gardner PI, Albala A, Fenoglio JJ, Wit AL. Structural and electrophysiological changes in the epicardial border zone of canine myocardial infarcts during infarct healing. Circ Res. 1985;56:436-451. (Pubitemid 15119520)
32. Wong SS, Bassett AL, Cameron JS, Epstein K, Kozlovskis P, Myerburg RJ. Dissimilarities in the electrophysiological abnormalities of lateral border and central infarct zone cells after healing of myocardial infarction in cats. Circ Res. 1982;51:486-493. (Pubitemid 12034488)
33. Camelliti P, Devlin GP, Matthews KG, Kohl P, Green CR. Spatially and temporally distinct expression of fibroblast connexins after sheep ventricular infarction. Cardiovasc Res. 2004;62:415-425. (Pubitemid 38496554)
34. Dillon SM, Allessie MA, Ursell PC, Wit AL. Influences of anisotropic tissue structure on reentrant circuits in the epicardial border zone of subacute canine infarcts. Circ Res. 1988;63:182-206.
35. Wang Y, Hill JA. Electrophysiological remodeling in heart failure. J Mol Cell Cardiol. 2010;48:619-632.
36. Young AA, LeGrice IJ, Young MA, Smaill BH. Extended confocal microscopy of myocardial laminae and collagen network. J Microscopy. 1998;192:139-150. (Pubitemid 28539618)