Endothelial glycocalyx degradation induces endogenous heparinization in patients with severe injury and early traumatic coagulopathy

Journal of Trauma and Acute Care Surgery

Volumn 73, Issue 1, 2012, Pages 60-66

  Ostrowski, Sisse R ^a   Johansson, Pär I ^b  

^a Mental Health Center Glostrup   (Denmark)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Trauma; thrombelastography; trauma induced coagulopathy; endothelial glycocalyx; endogenous heparinization.

Indexed keywords

ACTIVATED PROTEIN C; ADRENALIN; ANTITHROMBIN; BLOOD CLOTTING FACTOR 13; DNA FRAGMENT; FIBRINOGEN; GLUCOSE; HEMOGLOBIN; INTERLEUKIN 6; NORADRENALIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN C; PROTHROMBIN; PROTHROMBIN FRAGMENT 1+2; SYNDECAN 1; THROMBOMODULIN; TISSUE FACTOR PATHWAY INHIBITOR; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR;

ADRENERGIC SYSTEM; ADULT; ANTICOAGULATION; ARTICLE; BLOOD CLOTTING; BLOOD CLOTTING DISORDER; BLOOD TRANSFUSION; CELL DAMAGE; DEGRADATION; EMERGENCY HEALTH SERVICE; ENDOTHELIAL GLYCOCALYX; FEMALE; FIBRINOLYSIS; GLYCOCALYX; HEMOSTASIS; HEPARINIZATION; HUMAN; INFLAMMATION; INJURY; INJURY SCALE; INTERNATIONAL NORMALIZED RATIO; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; THROMBOELASTOGRAPHY; TISSUE INJURY; TRAUMA INDUCED COAGULOPATHY;

ADULT; BLOOD COAGULATION DISORDERS; BLOOD TRANSFUSION; ENDOTHELIUM, VASCULAR; FEMALE; GLYCOCALYX; HEPARIN; HUMANS; INJURY SEVERITY SCORE; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; SYNDECAN-1; THROMBELASTOGRAPHY; THROMBOMODULIN; WOUNDS AND INJURIES;

EID: 84864242336     PISSN: 21630755     EISSN: 21630763     Source Type: Journal    
DOI: 10.1097/TA.0b013e31825b5c10     Document Type: Article

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