Symptomatic osteonecrosis of the femoral head after adult orthotopic liver transplantation

Chinese Medical Journal

Volumn 125, Issue 14, 2012, Pages 2422-2426

  Li, Hua ^a   Zhang, Jian ^a   He, Ji Wen ^a   Wang, Kun ^a   Wang, Gen Shu ^a   Jiang, Nan ^a   Fu, Bin Sheng ^a   Wang, Guo Ying ^a   Yang, Yang ^a   Chen, Gui Hua ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Femoral head; Immunosuppression; Liver transplantation; Osteonecrosis; Treatment

Indexed keywords

ALKALINE PHOSPHATASE; BASILIXIMAB; BILIRUBIN; CALCIUM ION; CHOLESTEROL; CREATININE; CYCLOSPORIN A; DACLIZUMAB; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; RAPAMYCIN; TACROLIMUS; TRIACYLGLYCEROL;

ADULT; AGED; ARTICLE; BONE NECROSIS; CHINA; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; FEMALE; FEMUR HEAD; FOLLOW UP; GENDER; HIP ARTHROPLASTY; HUMAN; INCIDENCE; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; POST TREATMENT SURVIVAL; RETROSPECTIVE STUDY; RISK FACTOR; UREA NITROGEN BLOOD LEVEL;

ADULT; AGED; CYCLOSPORINE; FEMALE; FEMUR HEAD NECROSIS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LIVER TRANSPLANTATION; MALE; METHYLPREDNISOLONE; MIDDLE AGED; OSTEONECROSIS; RETROSPECTIVE STUDIES; RISK FACTORS; SIROLIMUS; TACROLIMUS; YOUNG ADULT;

EID: 84864199298     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2012.14.004     Document Type: Article

References (25)

1. Guichelaar MM, Schmoll J, Malinchoc M, Hay JE. Fractures and avascular necrosis before and after orthotopic liver transplantation: long-term follow-up and predictive factors. Hepatology 2007; 46: 1198-1207.
2. Jones LC, Hungerford DS. Osteonecrosis: etiology, diagnosis, and treatment. Curr Opin Rheumatol 2004; 16: 443-449.
3. Ficat RP. Idiopathic bone necrosis of the femoral head. Early diagnosis and treatment. J Bone Joint Surg Br 1985; 67: 3-9.
4. Julian BA, Quarles LD, Niemann KM. Musculoskeletal complications after renal transplantation: pathogenesis and treatment. Am J Kidney Dis 1992; 19: 99-120.
5. Hedri H, Cherif M, Zouaghi K, Abderrahim E, Goucha R, Ben HF, et al. Avascular osteonecrosis after renal transplantation. Transplant Proc 2007; 39: 1036-1038.
6. Taillandier J, Alemanni M, Samuel D, Bismuth H. Rheumatic complications following liver transplantation. Transplant Proc 1999; 31: 1717-1718.
7. Lieberman JR, Scaduto AA, Wellmeyer E. Symptomatic osteonecrosis of the hip after orthotopic liver transplantation. J Arthroplasty 2000; 15: 767-771.
8. Horiuchi H, Hashikura Y, Hisa K, Saito N, Ikegami T, Nakazawa Y, et al. Osteonecrosis of the femoral head in Japanese adults after liver transplantation: a preliminary report. J Orthop Sci 2004; 9: 119-121.
9. Lieberman JR, Roth KM, Elsissy P, Dorey FJ, Kobashigawa JA. Symptomatic osteonecrosis of the hip and knee after cardiac transplantation. J Arthroplasty 2008; 23: 90-96.
10. O'Brien CA, Jia D, Plotkin LI, Bellido T, Powers CC, Stewart SA, et al. Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strength. Endocrinology 2004; 145: 1835-1841.
11. Tsuji M, Ikeda H, Ishizu A, Miyatake Y, Hayase H, Yoshiki T. Altered expression of apoptosis-related genes in osteocytes exposed to high-dose steroid hormones and hypoxic stress. Pathobiology 2006; 73: 304-309.
12. Wolverton SE. Can short courses of systemic corticosteroids truly cause osteonecrosis. Dermatol Ther 2009; 22: 458-464.
13. Shibatani M, Fujioka M, Arai Y, Takahashi K, Ueshima K, Okamoto M, et al. Degree of corticosteroid treatment within the first 2 months of renal transplantation has a strong influence on the incidence of osteonecrosis of the femoral head. Acta Orthop 2008; 79: 631-636.
14. Helenius I, Jalanko H, Remes V, Tervahartiala P, Salminen S, Sairanen H, et al. Avascular bone necrosis of the hip joint after solid organ transplantation in childhood: a clinical and MRI analysis. Transplantation 2006; 81: 1621-1627.
15. Abbott KC, Koff J, Bohen EM, Oglesby RJ, Agodoa LY, Lentine KL, et al. Maintenance immunosuppression use and the associated risk of avascular necrosis after kidney transplantation in the United States. Transplantation 2005; 79: 330-336.
16. Jones LC, Hungerford DS. The pathogenesis of osteonecrosis. Instr Course Lect 2007; 56: 179-196.
17. Ajmal M, Matas AJ, Kuskowski M, Cheng EY. Does statin usage reduce the risk of corticosteroid-related osteonecrosis in renal transplant population. Orthop Clin North Am 2009; 40: 235-239.
18. Llach F, Fernandez E. Overview of renal bone disease: causes of treatment failure, clinical observations, the changing pattern of bone lesions, and future therapeutic approach. Kidney Int Suppl 2003: S113-S119.
19. Pritchett JW. Statin therapy decreases the risk of osteonecrosis in patients receiving steroids. Clin Orthop Relat Res 2001; 386: 173-178.
20. Lai KA, Shen WJ, Yang CY, Shao CJ, Hsu JT, Lin RM. The use of alendronate to prevent early collapse of the femoral head in patients with nontraumatic osteonecrosis. A randomized clinical study. J Bone Joint Surg Am 2005; 87: 2155-2159.
21. Marker DR, Seyler TM, McGrath MS, Delanois RE, Ulrich SD, Mont MA. Treatment of early stage osteonecrosis of the femoral head. J Bone Joint Surg Am 2008; 90 Suppl 4: 175-187.
22. Tannenbaum DA, Matthews LS, Grady-Benson JC. Infection around joint replacements in patients who have a renal or liver transplantation. J Bone Joint Surg Am 1997; 79: 36-43.
23. Levitsky J, Te HS, Cohen SM. The safety and outcome of joint replacement surgery in liver transplant recipients. Liver Transpl 2003; 9: 373-376.
24. Goffin E, Baertz G, Rombouts JJ. Long-term survivorship analysis of cemented total hip replacement (THR) after avascular necrosis of the femoral head in renal transplant recipients. Nephrol Dial Transplant 2006; 21: 784-788.
25. Sayed-Noor AS. Joint arthroplasties other than the hip in solid organ transplant recipients. Open Orthop J 2009; 3: 27-31.