Permutation-based approaches do not adequately allow for linkage disequilibrium in gene-wide multi-locus association analysis

European Journal of Human Genetics

Volumn 20, Issue 8, 2012, Pages 890-896

  Moskvina, Valentina ^a   Schmidt, Karl M ^a   Vedernikov, Alexey ^a   Owen, Michael J ^a   Craddock, Nicholas ^a   Holmans, Peter ^a   O'Donovan, Michael C ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

correlated tests; gene wide analysis; GWAS

Indexed keywords

ARTICLE; CONTROLLED STUDY; DATA ANALYSIS; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC MARKER; HUMAN; MULTILOCUS SEQUENCE TYPING; PERMUTATION TEST; PRIORITY JOURNAL; SAMPLING ERROR; SIMULATION; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL ANALYSIS;

ALGORITHMS; COMPUTER SIMULATION; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; LINKAGE DISEQUILIBRIUM; MODELS, GENETIC; MODELS, STATISTICAL; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84864152039     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/ejhg.2012.8     Document Type: Article

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