Design and generation of DVD-Ig™ molecules for dual-specific targeting

Methods in Molecular Biology

Volumn 899, Issue , 2012, Pages 145-156

  Digiammarino, Enrico ^a   Ghayur, Tariq ^a   Liu, Junjian ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Antibody engineering; Dual variable domain immunoglobulin; Dual specific targeting; DVD Ig; Immunotherapy; Linker; Monoclonal antibody; Variable domain

Indexed keywords

IMMUNOGLOBULIN; MONOCLONAL ANTIBODY;

ANTIBODY SPECIFICITY; ARTICLE; CHEMISTRY; HUMAN; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOTHERAPY; ISOLATION AND PURIFICATION; METHODOLOGY; PROTEIN ENGINEERING; PROTEIN TERTIARY STRUCTURE;

ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; HUMANS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOGLOBULINS; IMMUNOTHERAPY; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY;

EID: 84864151968     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-921-1_9     Document Type: Article

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