The sulfated polysaccharide fucoidan stimulates osteogenic differentiation of human adipose-derived stem cells

Stem Cells and Development

Volumn 21, Issue 12, 2012, Pages 2204-2211

  Park, Soo Jeong ^a   Lee, Kyo Won ^b   Lim, Dae Seog ^a   Lee, Suman ^a  

^a CHA University   (South Korea)

^b Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

5' NUCLEOTIDASE; ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE; ALIZARIN RED S; ALKALINE PHOSPHATASE; ALPHA SMOOTH MUSCLE ACTIN; CD34 ANTIGEN; CD45 ANTIGEN; COLLAGEN TYPE 1; ENDOGLIN; FUCOIDIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GROWTH FACTOR; HEPARIN; HLA DR ANTIGEN; OSTEOPONTIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; POLYSACCHARIDE; SULFATE; THY 1 ANTIGEN; TRANSCRIPTION FACTOR RUNX2;

ADIPOSE DERIVED STEM CELL; ADIPOSE TISSUE; ALP GENE; AMNIOTIC FLUID CELL; AMNIOTIC FLUID STEM CELL; ARTICLE; BONE DEVELOPMENT; BONE REGENERATION; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; MARKER GENE; MESENCHYME CELL; OSTEOCALCIN GENE; OSTEOPONTIN GENE; PRIORITY JOURNAL; REGULATORY MECHANISM; RUNT RELATED TRANSCRIPTION FACTOR 2 GENE; SIGNAL TRANSDUCTION; STAINING; TYPE I COLLAGEN GENE; VON KOSSA STAINING;

ADULT STEM CELLS; ALKALINE PHOSPHATASE; ANTIGENS, CD; CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; CELLS, CULTURED; EXTRACELLULAR MATRIX; GENE EXPRESSION; HUMANS; MESENCHYMAL STROMAL CELLS; OSTEOGENESIS; PHENOTYPE; POLYSACCHARIDES; SUBCUTANEOUS FAT;

EID: 84864147725     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2011.0521     Document Type: Article

References (36)

1. De Ugarte DA, K Morizono, A Elbarbary, Z Alfonso, PA Zuk, M Zhu, JL Dragoo, P Ashjian, B Thomas, et al. (2003). Comparison of multi-lineage cells from human adipose tis-sue and bone marrow. Cells Tissues Organs 174:101-109.
2. Oishi K, H Noguchi, H Yukawa and S Hayashi. (2009). Differential ability of somatic stem cells. Cell Transplant 18:581-589.
3. Satija NK, GU Gurudutta, S Sharma, F Afrin, P Gupta, YK Verma, VK Singh and RP Tripathi. (2007). Mesenchymal stem cells: molecular targets for tissue engineering. Stem Cells Dev 16:7-23.
4. Bunnell BA, BT Estes, F Guilak and JM Gimble. (2008). Differentiation of adipose stem cells. Methods Mol Biol 456: 155-171.
5. Meliga E, BM Strem, HJ Duckers and PW Serruys. (2007). Adipose-derived cells. Cell Transplant 16:963-970.
6. Strem BM, KC Hicok, M Zhu, I Wulur, Z Alfonso, RE Schreiber, JK Fraser and MH Hedrick. (2005). Multipotential differentiation of adipose tissue-derived stem cells. Keio J Med 54:132-141.
7. Zuk PA, M Zhu, P Ashjian, DA De Ugarte, JI Huang, H Mizuno, ZC Alfonso, JK Fraser, P Benhaim and MH He-drick. (2002). Human adipose tissue is a source of multi-potent stem cells. Mol Biol Cell 13:4279-4295.
8. Zuk PA, M Zhu, H Mizuno, J Huang, JW Futrell, AJ Katz, P Benhaim, HP Lorenz and MH Hedrick. (2001). Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng 7:211-228.
9. Elabd C, C Chiellini, A Massoudi, O Cochet, LE Zaragosi, C Trojani, JF Michiels, P Weiss, G Carle, et al. (2007). Human adipose tissue-derived multipotent stem cells differentiate in vitro and in vivo into osteocyte-like cells. Biochem Biophys Res Commun 361:342-348.
10. Hattori H, M Sato, K Masuoka, M Ishihara, T Kikuchi, T Matsui, B Takase, T Ishizuka, M Kikuchi and K Fujikawa. (2004). Osteogenic potential of human adipose tissue-derived stromal cells as an alternative stem cell source. Cells Tissues Organs 178:2-12.
11. Weinzierl K, A Hemprich and B Frerich. (2006). Bone engi-neering with adipose tissue derived stromal cells. J Cranio-maxillofac Surg 34:466-471.
12. Zhu M, E Kohan, J Bradley, M Hedrick, P Benhaim and P Zuk. (2009). The effect of age on osteogenic, adipogenic and proliferative potential of female adipose-derived stem cells. J Tissue Eng Regen Med 3:290-301.
13. Liao X, F Li, X Wang, J Yanoso and C Niyibizi. (2008). Distribution of murine adipose-derived mesenchymal stem cells in vivo following transplantation in developing mice. Stem Cells Dev 17:303-314.
14. Jethva R, S Otsuru, M Dominici and EM Horwitz. (2009). Cell therapy for disorders of bone. Cytotherapy 11:3-17.
15. Panetta NJ, DM Gupta and MT Longaker. Bone regeneration and repair. Curr Stem Cell Res Ther 5:122-128.
16. Seong JM, BC Kim, JH Park, IK Kwon, A Mantalaris and YS Hwang. Stem cells in bone tissue engineering. Biomed Mater 5:062001.
17. Blanquaert F, JL Saffar, ML Colombier, G Carpentier, D Barritault and JP Caruelle. (1995). Heparan-like molecules induce the repair of skull defects. Bone 17:499-506.
18. Manton KJ, DF Leong, SM Cool and V Nurcombe. (2007). Disruption of heparan and chondroitin sulfate signaling enhances mesenchymal stem cell-derived osteogenic differ-entiation via bone morphogenetic protein signaling path-ways. Stem Cells 25:2845-2854.
19. Jiao X, PC Billings, MP O'Connell, FS Kaplan, EM Shore and DL Glaser. (2007). Heparan sulfate proteoglycans (HSPGs) modulate BMP2 osteogenic bioactivity in C2C12 cells. J Biol Chem 282:1080-1086.
20. Durand E, D Helley, A Al Haj Zen, C Dujols, P Bruneval, S Colliec-Jouault, AM Fischer and A Lafont. (2008). Effect of low molecular weight fucoidan and low molecular weight heparin in a rabbit model of arterial thrombosis. J Vasc Res 45:529-537.
21. Li B, F Lu, X Wei and R Zhao. (2008). Fucoidan: structure and bioactivity. Molecules 13:1671-1695.
22. Matou S, D Helley, D Chabut, A Bros and AM Fischer. (2002). Effect of fucoidan on fibroblast growth factor-2-induced angiogenesis in vitro. Thromb Res 106:213-221.
23. Senni K, F Gueniche, A Foucault-Bertaud, S Igondjo-Tchen, F Fioretti, S Colliec-Jouault, P Durand, J Guezennec, G Godeau and D Letourneur. (2006). Fucoidan a sulfated polysaccharide from brown algae is a potent modulator of connective tissue proteolysis. Arch Biochem Biophys 445: 56-64.
24. Changotade SI, G Korb, J Bassil, B Barroukh, C Willig, S Colliec-Jouault, P Durand, G Godeau and K Senni. (2008). Potential effects of a low-molecular-weight fucoidan ex-tracted from brown algae on bone biomaterial osteo-conductive properties. J Biomed Mater Res A 87:666-675.
25. Berteau O and B Mulloy. (2003). Sulfated fucans, fresh per-spectives: structures, functions, and biological properties of sulfated fucans and an overview of enzymes active toward this class of polysaccharide. Glycobiology 13:29R-40R
26. Sithranga Boopathy N and K Kathiresan. (2010). Anticancer drugs from marine flora: an overview. J Oncol 2010:214186.
27. Chevolot L, B Mulloy, J Ratiskol, A Foucault and S Colliec-Jouault. (2001). A disaccharide repeat unit is the major structure in fucoidans from two species of brown algae. Carbohydr Res 330:529-535.
28. Ling L, S Murali, C Dombrowski, LM Haupt, GS Stein, AJ van Wijnen, V Nurcombe and SM Cool. (2006). Sulfated glycosaminoglycans mediate the effects of FGF2 on the os-teogenic potential of rat calvarial osteoprogenitor cells. J Cell Physiol 209:811-825.
29. Cumashi A, NA Ushakova, ME Preobrazhenskaya, A D'In-cecco, A Piccoli, L Totani, N Tinari, GE Morozevich, AE Berman, et al. (2007). A comparative study of the anti-inflammatory, anticoagulant, antiangiogenic, and antiadhesive activities of nine different fucoidans from brown seaweeds. Glycobiology 17:541-552.
30. Maruyama H, H Tamauchi, M Iizuka and T Nakano. (2006). The role of NK cells in antitumor activity of dietary fucoidan from Undaria pinnatifida sporophylls (Mekabu). Planta Med 72:1415-1417
31. Mourao PA. (2004). Use of sulfated fucans as anticoagulant and antithrombotic agents: future perspectives. Curr Pharm Des 10:967-981.
32. Walsh S, C Jefferiss, K Stewart, GR Jordan, J Screen and JN Beresford. (2000). Expression of the developmental markers STRO-1 and alkaline phosphatase in cultures of human marrow stromal cells: regulation by fibroblast growth factor (FGF)-2 and relationship to the expression of FGF receptors 1-4. Bone 27:185-195.
33. Komori T, H Yagi, S Nomura, A Yamaguchi, K Sasaki, K Deguchi, Y Shimizu, RT Bronson, YH Gao, et al. (1997). Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 89:755-764.
34. Ducy P, R Zhang, V Geoffroy, AL Ridall and G Karsenty. (1997). Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell 89:747-754.
35. Cooper MS, M Hewison and PM Stewart. (1999). Gluco-corticoid activity, inactivity and the osteoblast. J Endocrinol 163:159-164.
36. Kim KJ, OH Lee and BY Lee. (2010). Fucoidan, a sulfated polysaccharide, inhibits adipogenesis through the mitogen-activated protein kinase pathway in 3T3-L1 preadipocytes. Life Sci 86:791-797.