Simultaneous determination of primaquine and carboxyprimaquine in plasma using solid phase extraction and LC-MS assay

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 902, Issue , 2012, Pages 142-146

  Page Sharp, Madhu ^a   Ilett, Kenneth F ^b   Betuela, Inoni ^c   Davis, Timothy M E ^b   Batty, Kevin T ^a,d  

^a CURTIN UNIVERSITY   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c PAPUA NEW GUINEA INSTITUTE OF MEDICAL RESEARCH   (Papua New Guinea)

^d CURTIN UNIVERSITY   (Australia)

Author keywords

Carboxyprimaquine; LC MS; Plasma; Primaquine; Solid phase extraction

Indexed keywords

8-AMINOQUINOLINE; ACTIVE METABOLITES; ANALYTES; BIOANALYTICAL METHODS; CALIBRATION CURVES; CARBOXYPRIMAQUINE; CONCENTRATION RANGES; HUMAN PLASMAS; INTERNAL STANDARDS; LC-MS; LC-MS METHODS; LIMITS OF QUANTIFICATION; MOBILE PHASE; NUMBER OF SAMPLES; PHARMACOKINETIC STUDIES; PLASMA CONCENTRATION; PRIMAQUINE; RETENTION TIME; RUNTIMES; SELECTED ION MONITORING; SHIMADZU; SIMULTANEOUS ANALYSIS; SIMULTANEOUS DETERMINATIONS; SOLID-PHASE EXTRACTION;

CHEMICAL ANALYSIS; FORMIC ACID; METHANOL; PLASMA (HUMAN); PLASMAS;

AMINES;

4 (6 METHOXY 8 QUINOLYLAMINO)VALERIC ACID; 8 AMINOQUINOLINE DERIVATIVE; FORMIC ACID; METHANOL; PRIMAQUINE; PRIMAQUINE DERIVATIVE; UNCLASSIFIED DRUG; WATER;

ACCURACY; ARTICLE; BLOOD SAMPLING; CASE REPORT; CHILD; DRUG BLOOD LEVEL; ENVIRONMENTAL TEMPERATURE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; PRIORITY JOURNAL; SCHOOL CHILD; SENSITIVITY ANALYSIS; SOLID PHASE EXTRACTION;

CHILD; CHROMATOGRAPHY, LIQUID; FEMALE; HUMANS; MALE; PRIMAQUINE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84864109892     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2012.06.019     Document Type: Article

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