Effect of turmeric (Curcuma longa) on overweight hyperlipidemic subjects: Double blind study

Indian Journal of Community Health

Volumn 24, Issue 2, 2012, Pages 107-112

  Pashine, Lekhani ^a   Singh, J V ^a   Vaish, A K ^b   Ojha, S K ^a   Mehdi, A ^b  

^a KING GEORGE'S MEDICAL UNIVERSITY   (India)

^b National Institute of Botanical Research Institue   (India)

Author keywords

Double blind; Hyperlipidemic effect; Turmeric

Indexed keywords

EID: 84864091375     PISSN: 09717587     EISSN: 22489509     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Anto RJ, Mukhopadhyay A, Denning K, Aggarwal BB. Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: its suppression by ectopic expression of Bcl-2 and Bcl-xl. Carcinogenesis. 2002; 23(1): 143-150.
2. Cheng Y, Kozubek A, Ohlsson L, Sternby B, Duan RD. Curcumin decreases acid sphingomyelinase activity in colon cancer Caco-2 cells. Planta Med. 2007; 73(8): 725-730.
3. Sandur SK, Ichikawa H, Pandey MK, Kunnumakkara AB, Sung B, Sethi G, Aggarwal BB. Role of pro-oxidants and antioxidants in the anti-inflammatory and apoptotic effects of curcumin (diferuloylmethane). Free Radic Biol Med. 2007; 43(4): 568-580.
4. Rao DS, Sekhara NC, Satyanarayana MN, Srinivasan M. Effect of curcumin on serum and liver cholesterol levels in the rat. J. Nutr. 1970; 100 (11), 1307-1315.
5. Asai A, Miyazawa T. Dietary curcuminoids prevent high-fat diet-induced lipid accumulation in rat liver and epididymal adipose tissue. J Nutr. 2001; 131(11): 2932-2935.
6. Babu PS, Srinivasan K. Hypolipidemic action of curcumin, the active principle of turmeric (Curcuma longa) in streptozotocin induced diabetic rats. Mol Cell Biochem. 1997; 166(1-2): 169-175.
7. Ramirez-Tortosa MC, Mesa MD, Aguilera MC, Quiles JL, Baro L, Ramirez-Tortosa CL, Martinez-Victoria E, Gil A. Oral administration of a turmeric extract inhibits LDL oxidation and has hypocholesterolemic effects in rabbits with experimental atherosclerosis. Atherosclerosis. 1999; 147(2): 371-378.
8. Alwi I, Santoso T, Suyono S, Sutrisna B, Suyatna FD, Kresno SB, Ernie S. The effect of curcumin on lipid level in patients with acute coronary syndrome. Acta Med Indones. 2008; 40(4): 201-210.
9. Baum L, Cheung SK, Mok VC, Lam LC, Leung VP, Hui E, Ng CC, Chow M, Ho PC, Lam S, et al. Curcumin effects on blood lipid profile in a 6-month human study. Pharmacol Res. 2007; 56(6): 509-514.
10. Soni KB, Kuttan R. Effect of oral curcumin administration on serum peroxides and cholesterol levels in human volunteers. Indian J Physiol Pharmacol. 1992; 36(4): 273-275.
11. Peschel D, Koerting R, Nass N. Curcumin induces changes in expression of genes involved in cholesterol homeostasis. J Nutr Biochem. 2007; 18(2): 113-119.
12. Dou X, Fan C, Wo L, Yan J, Qian Y, Wo X. Curcumin up-regulates LDL receptor expression via the sterol regulatory element pathway in HepG2 cells. Planta Med. 2008; 74(11): 1374-1379.
13. Patil TN, Srinivasan M. Hypocholesteremic effect of curcumin in induced hypercholesteremic rats. Indian J. Exp. Biol. 1971; 9(2): 167-169.
14. Keshavarz K. The influence of turmeric and curcumin on cholesterol concentration of eggs and tissues. Poult. Sci. 1976; 55(3): 1077-1083.
15. Soudamini KK, Unnikrishnan MC, Soni KB, Kuttan R. Inhibition of lipid peroxidation and cholesterol levels in mice by curcumin. Indian J. Physiol. Pharmacol. 1992; 36(4): 239-243.
16. Aggarwal BB, Kumar A, Aggarwal MS, Shishodia S. Curcumin Derived from Turmeric (Curcuma longa): a Spice for All Seasons. 2005 by CRC Press LLC