Loss of TMF/ARA160 protein renders colonic mucus refractory to bacterial colonization and diminishes intestinal susceptibility to acute colitis

Journal of Biological Chemistry

Volumn 287, Issue 30, 2012, Pages 25631-25639

  Bel, Shai ^a   Elkis, Yoav ^a   Lerer Goldstein, Tali ^a   Nyska, Abraham ^b   Shpungin, Sally ^a   Nir, Uri ^a  

^a BAR ILAN UNIVERSITY   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL COLONIES; BACTERIAL COLONIZATION; BACTERIAL RETENTIONS; CELLULAR FUNCTION; COLON TISSUES; DEXTRAN SULFATE SODIUM; GENE EXPRESSION ANALYSIS; IN-VIVO; INTESTINAL EPITHELIAL CELLS; LARGE INTESTINE; MUCUS-GEL; PROTEASOMAL DEGRADATION; STRESS CONDITION; UBIQUITINATION; WILD TYPES;

CELL PROLIFERATION; DEGRADATION; DISEASES; GENES; MAMMALS; REFRACTORY MATERIALS; SODIUM; TISSUE; TRANSCRIPTION;

BODY FLUIDS;

ARA 160 PROTEIN; CELL PROTEIN; DEXTRAN SULFATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MUCIN; MUCIN 2; PROTEIN BCL XL; TMF PROTEIN; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL COLONIZATION; CELL PROLIFERATION; COLITIS; COLON MUCOSA; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; DISEASE COURSE; DISEASE PREDISPOSITION; FEMALE; HISTOPATHOLOGY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; UPREGULATION;

ANIMALS; BACTERIA; BACTERIAL TRANSLOCATION; COLITIS; COLON; DEXTRAN SULFATE; IMMUNITY, INNATE; INTESTINAL MUCOSA; MICE; MICE, KNOCKOUT; MUCIN-2; TRANSCRIPTION FACTOR RELA; UBIQUITIN-PROTEIN LIGASES; VESICULAR TRANSPORT PROTEINS;

BACTERIA (MICROORGANISMS); MUS;

EID: 84864090540     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.364786     Document Type: Article

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