메뉴 건너뛰기




Volumn 16, Issue 5, 2012, Pages 667-671

A review on an update of NS5B polymerase hepatitis C virus inhibitors

Author keywords

Hepatitis; Interferon; NS3; NS5B

Indexed keywords

GLYCOPROTEIN E1; GLYCOPROTEIN E2; GSK 625433; MERICITABINE; MK 0608; MONOCLONAL ANTIBODY; NESBUVIR; NONSTRUCTURAL PROTEIN 2; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 4A; NONSTRUCTURAL PROTEIN 4B; NONSTRUCTURAL PROTEIN 5A; NONSTRUCTURAL PROTEIN 5B; NUCLEOSIDE DERIVATIVE; RNA DIRECTED RNA POLYMERASE INHIBITOR; UNCLASSIFIED DRUG; VCH 759; VCH 916; VIRUS RNA; ANTIVIRUS AGENT; ENZYME INHIBITOR; NS 5 PROTEIN, HEPATITIS C VIRUS; NS-5 PROTEIN, HEPATITIS C VIRUS; VIRUS PROTEIN;

EID: 84864089619     PISSN: 11283602     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (14)

References (28)
  • 1
    • 84864262841 scopus 로고    scopus 로고
    • Recent advances in the development on NS5B polymerase inhibitors for the treatment of hepatitis C virus infection
    • ADACHI T, AGO H, HABUKA N. Recent advances in the development on NS5B polymerase inhibitors for the treatment of hepatitis C virus infection. Biochem Biophys Acta 2002; 39: 1601.
    • (2002) Biochem Biophys Acta , vol.39 , pp. 1601
    • Adachi, T.1    Ago, H.2    Habuka, N.3
  • 2
    • 33847676761 scopus 로고    scopus 로고
    • Structure and functions of hepatitis C virus proteins
    • SHEPARD CW, ALTER MJ. Structure and functions of hepatitis C virus proteins. Lancet 2005; 5: 524.
    • (2005) Lancet , vol.5 , pp. 524
    • Shepard, C.W.1    Alter, M.J.2
  • 3
    • 7044231396 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Recent trends in United States
    • EL-SERAG HB. Hepatocellular carcinoma: Recent trends in United States. Gastroenterology 2004; 5: S27-S34.
    • (2004) Gastroenterology , vol.5
    • El-Serag, H.B.1
  • 4
    • 0036139972 scopus 로고    scopus 로고
    • Rice, the way forwarding HCV treatment-finding the right
    • DI BISCEGLIE AM, MC HUTCHISON JC. Rice, the way forwarding HCV treatment-finding the right. Hepatology 2002; 35: 224-231.
    • (2002) Hepatology , vol.35 , pp. 224-231
    • D.I. Bisceglie, A.M.1    M.C. Hutchison, J.C.2
  • 5
    • 0036835590 scopus 로고    scopus 로고
    • Hep C therapeutics: Current status and emerging strategies
    • TAN SL, PAUSE A, SHI Y. Hep C therapeutics: Current status and emerging strategies. Nat Rev Drug Disc 2002; 1: 867-881.
    • (2002) Nat Rev Drug Disc , vol.1 , pp. 867-881
    • Tan, S.L.1    Pause, A.2    Shi, Y.3
  • 6
    • 67649303095 scopus 로고    scopus 로고
    • Recent advances in the development on NS5B polymerase
    • BEAULIEU P-L. Recent advances in the development on NS5B polymerase. Expert Opin Ther Pat 2009; 19: 145.
    • (2009) Expert Opin Ther Pat , vol.19 , pp. 145
    • Beaulieu, P.-L.1
  • 8
    • 0036835590 scopus 로고    scopus 로고
    • Hepatitis C therapeutics: Current status and emerging strategies
    • TAN SL, PAUSE A, SHI Y, SONENBERG N. Hepatitis C therapeutics: Current status and emerging strategies. Nat Rev Drug Disc 2002; 1: 867-881.
    • (2002) Nat Rev Drug Disc , vol.1 , pp. 867-881
    • Tan, S.L.1    Pause, A.2    Shi, Y.3    Sonenberg, N.4
  • 13
    • 50949115626 scopus 로고    scopus 로고
    • A hepatitis C virus cis-acting replication element forms a longrange RNA-RNA interaction with upstream RNA sequences in NS5B
    • DIVINEY S, TUPLIN A, STRUTHERS M. A hepatitis C virus cis-acting replication element forms a longrange RNA-RNA interaction with upstream RNA sequences in NS5B. J Virol 2008; 18: 9008-9022.
    • (2008) J Virol , vol.18 , pp. 9008-9022
    • Diviney, S.1    Tuplin, A.2    Struthers, M.3
  • 14
    • 0037379425 scopus 로고    scopus 로고
    • Hepatitis C virus RNA replication occurs on a detergentresistant membrane that co fractionates with caveolin-2
    • SHI ST, LEE KJ, AIZAKI H, HWANG SB, LAI MM. Hepatitis C virus RNA replication occurs on a detergentresistant membrane that co fractionates with caveolin-2. J Virol 2003; 7: 4160-4168.
    • (2003) J Virol , vol.7 , pp. 4160-4168
    • Shi, S.T.1    Lee, K.J.2    Aizaki, H.3    Hwang, S.B.4    Lai, M.M.5
  • 16
    • 70350142577 scopus 로고    scopus 로고
    • Hepatitis C virus: Viral proteins on the move
    • MCLAUCHLAN J. Hepatitis C virus: Viral proteins on the move. Biochem Soc Trans 2009; 37: 986-990.
    • (2009) Biochem Soc Trans , vol.37 , pp. 986-990
    • Mclauchlan, J.1
  • 17
    • 23944485662 scopus 로고    scopus 로고
    • Evasion of intracellular host defence by hepatitis C virus
    • GALE M, FOY EM. Evasion of intracellular host defence by hepatitis C virus. Nature 2005; 5: 939-945.
    • (2005) Nature , vol.5 , pp. 939-945
    • Gale, M.1    Foy, E.M.2
  • 18
    • 33847136509 scopus 로고    scopus 로고
    • Structure and functions of hepatitis C virus proteins: 15 years after
    • KREKULOVA L, REHAK V, RILEY L-W. Structure and functions of hepatitis C virus proteins: 15 years after. Folia Microbiol (Praha) 2006; 51: 665-680.
    • (2006) Folia Microbiol (Praha) , vol.51 , pp. 665-680
    • Krekulova, L.1    Rehak, V.2    Riley, L.-W.3
  • 19
    • 66149135640 scopus 로고    scopus 로고
    • Tumor suppressors, chromosomal instability and hepatitis C virus-associated liver cancer
    • MCGIVERN DR, LEMON SM. Tumor suppressors, chromosomal instability and hepatitis C virus-associated liver cancer. Annu Rev Pathol 2009; 4: 399-415.
    • (2009) Annu Rev Pathol , vol.4 , pp. 399-415
    • Mcgivern, D.R.1    Lemon, S.M.2
  • 20
    • 0027176287 scopus 로고
    • NS3 is a serine protease required for processing of hepatitis C virus polyprotein
    • TOMEI L. NS3 is a serine protease required for processing of hepatitis C virus polyprotein. J Virol 1993; 67: 4017-4026.
    • (1993) J Virol , vol.67 , pp. 4017-4026
    • Tomei, L.1
  • 21
    • 0028812617 scopus 로고
    • Intrafamilial transmission of hepatitis C virus among the population of an endemic area of Japan
    • NAKASHIMA K, IKEMATSU H, HAYASHI J, KISHIHARA Y. Intrafamilial transmission of hepatitis C virus among the population of an endemic area of Japan. JAMA 1995; 274: 1459-1460.
    • (1995) JAMA , vol.274 , pp. 1459-1460
    • Nakashima, K.1    Ikematsu, H.2    Hayashi, J.3    Kishihara, Y.4
  • 23
    • 0033854022 scopus 로고    scopus 로고
    • Evaluation of a new enzyme immunoassay for hepatitis C virus (HCV) core antigen with clinical sensitivity approximating that of genomic amplification of HCV RNA
    • TANAKA E, OHUE C, AOYAGI K, YAMAGUCHI K, YAGI S, KIYOSAWA K. Evaluation of a new enzyme immunoassay for hepatitis C virus (HCV) core antigen with clinical sensitivity approximating that of genomic amplification of HCV RNA. Hepatology 2000; 32: 388-393.
    • (2000) Hepatology , vol.32 , pp. 388-393
    • Tanaka, E.1    Ohue, C.2    Aoyagi, K.3    Yamaguchi, K.4    Yagi, S.5    Kiyosawa, K.6
  • 24
    • 0029135060 scopus 로고
    • Assessment of hepatitis C viremia using molecular amplification technologies: Correlations and clinical implications
    • GRETCH DR, DELA ROSA C, CARITHERS RL JR. Assessment of hepatitis C viremia using molecular amplification technologies: Correlations and clinical implications. Ann Intern Med 1995; 123: 321-329.
    • (1995) Ann Intern Med , vol.123 , pp. 321-329
    • Gretch, D.R.1    Dela Rosa, C.2    Carithers Rl, J.R.3
  • 25
    • 0028226834 scopus 로고
    • Detection and quantitation of serum HCV-RNA by branched DNA amplification in anti-HCV positive blood donors
    • MARTINOT-PEIGNOUX M, MARCELLIN P, GOURNAY J. Detection and quantitation of serum HCV-RNA by branched DNA amplification in anti-HCV positive blood donors. J Hepatol 1994; 20: 676-678.
    • (1994) J Hepatol , vol.20 , pp. 676-678
    • Martinot-Peignoux, M.1    Marcellin, P.2    Gournay, J.3
  • 26
    • 0025862146 scopus 로고
    • Molecular biology of the hepatitis viruses: Implications for diagnosis, development and control of viral disease
    • HOUGHTON M, WEINER AJ, HAN J, KUO G, CHOO QL. Molecular biology of the hepatitis viruses: Implications for diagnosis, development and control of viral disease. Hepatology 1991; 14: 382-388.
    • (1991) Hepatology , vol.14 , pp. 382-388
    • Houghton, M.1    Weiner, A.J.2    Han, J.3    Kuo, G.4    Choo, Q.L.5
  • 27
    • 0034030136 scopus 로고    scopus 로고
    • Cellular immune responses persist and humoral responses decrease two decades after recovery from a single source outbreak of hepatitis C
    • TAKAKI A, WIESE M, MAERTENS G, DEPLA E, SEIFERT U, LIEBETRAU A. Cellular immune responses persist and humoral responses decrease two decades after recovery from a single source outbreak of hepatitis C. Nat Med 2000; 6: 578-582.
    • (2000) Nat Med , vol.6 , pp. 578-582
    • Takaki, A.1    Wiese, M.2    Maertens, G.3    Depla, E.4    Seifert, U.5    Liebetrau, A.6
  • 28
    • 67650631316 scopus 로고    scopus 로고
    • HCV NS5B polymerase inhibitors
    • BURTON JR, EVERSON GT. HCV NS5B polymerase inhibitors. Clin Liver Dis 2009; 13: 453-465.
    • (2009) Clin Liver Dis , vol.13 , pp. 453-465
    • Burton, J.R.1    Everson, G.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.