Simultaneous measurement of heroin and its metabolites in brain extracellular fluid by microdialysis and ultra performance liquid chromatography tandem mass spectrometry

Journal of Pharmacological and Toxicological Methods

Volumn 66, Issue 1, 2012, Pages 14-21

  Gottas, A ^a   Oiestad, E L ^a   Boix, F ^a   Ripel, A ^a   Thaulow, C H ^a   Pettersen, B S ^a   Vindenes, V ^a   Morland, J ^a,b  

^a NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

Heroin; Metabolite kinetics; Microdialysis; Opiates; Pharmacokinetics; Retrodialysis

Indexed keywords

DIAMORPHINE; MORPHINE; MORPHINE 3 GLUCURONIDE; MORPHINE 6 ACETATE;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; BRAIN; BRAIN FUNCTION; CALIBRATION; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG RETENTION; EXTRACELLULAR FLUID; IONIZATION; LIMIT OF DETECTION; LIMIT OF QUANTITATION; MALE; MICRODIALYSIS; MOLECULAR WEIGHT; NONHUMAN; PHARMACOKINETICS; RAT; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ANIMALS; BRAIN; BRAIN CHEMISTRY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EXTRACELLULAR FLUID; HEROIN; INJECTIONS, INTRAVENOUS; MALE; MICRODIALYSIS; NARCOTICS; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

ANIMALIA; RATTUS;

EID: 84864076827     PISSN: 10568719     EISSN: 1873488X     Source Type: Journal    
DOI: 10.1016/j.vascn.2012.04.009     Document Type: Article

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