Role of endothelial AADC in cardiac synthesis of serotonin and nitrates accumulation

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Rouzaud Laborde, Charlotte ^a,b,c   Hanoun, Naïma ^a   Baysal, Ipek ^a,b   Rech, Jean Simon ^a,b   Mias, Céline ^a,b   Calise, Denis ^a,b   Sicard, Pierre ^a,b   Frugier, Céline ^a,b   Seguelas, Marie Helène ^a,b   Parini, Angelo ^a,b,c   Pizzinat, Nathalie ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ PAUL SABATIER   (France)

^c TOULOUSE UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXYTRYPTOPHAN; AROMATIC LEVO AMINO ACID DECARBOXYLASE; BENSERAZIDE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; NITRATE; SEROTONIN; TRYPTOPHAN HYDROXYLASE;

ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BIOSYNTHESIS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; HEART; MAST CELL; MAST CELL DEGRANULATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RAT;

5-HYDROXYTRYPTOPHAN; ANIMALS; AROMATIC-L-AMINO-ACID DECARBOXYLASES; BLOTTING, WESTERN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HEART; MICE; MYOCARDIUM; MYOCYTES, CARDIAC; NITRATES; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEROTONIN; TRYPTOPHAN HYDROXYLASE;

MUS; RATTUS;

EID: 84864067230     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0034893     Document Type: Article

References (31)

1. Watts SW, (2009) The love of a lifetime: 5-HT in the cardiovascular system. Am J Physiol Regul Integr Comp Physiol 296(2): R252-256.
2. Kaumann AJ, Levy FO, (2006) 5-hydroxytryptamine receptors in the human cardiovascular system. Pharmacol Ther 111(3): 674-706.
3. Villalon CM, Centurion D, (2007) Cardiovascular responses produced by 5-hydroxytriptamine:a pharmacological update on the receptors/mechanisms involved and therapeutic implications. Naunyn Schmiedebergs Arch Pharmacol 376(1-2): 45-63.
4. Takano S, Hoshino Y, Li L, Matsuoka I, Ono T, et al. (2004) Dual roles of 5-hydroxytryptamine in ischemia-reperfusion injury in isolated rat hearts. J Cardiovasc Pharmacol Ther 9(1): 43-50.
5. Bouchard JF, Chouinard J, Lamontagne D, (2000) Participation of prostaglandin E2 in the endothelial protective effect of ischaemic preconditioning in isolated rat heart. Cardiovasc Res 45(2): 418-427.
6. DeFily DV, Kuo L, Chilian WM, (1996) PAF attenuates endothelium-dependent coronary arteriolar vasodilation. Am J Physiol 270(6 Pt 2): H2094-2099.
7. Ellwood AJ, Curtis MJ, (1996) Mechanism of 5-hydroxytryptamine-induced coronary vasodilation assessed by direct detection of nitric oxide production in guinea-pig isolated heart. Br J Pharmacol 119(4): 721-729.
8. Wang W, Hein TW, Zhang C, Zawieja DC, Liao JC, et al. (2011) Oxidized low-density lipoprotein inhibits nitric oxide-mediated coronary arteriolar dilation by up-regulating endothelial arginase I. Microcirculation 18(1): 36-45.
9. Marcus ML, Chilian WM, Kanatsuka H, Dellsperger KC, Eastham CL, et al. (1990) Understanding the coronary circulation through studies at the microvascular level. Circulation 82(1): 1-7.
10. Zhang C, Hein TW, Wang W, Chang CI, Kuo L, (2001) Constitutive expression of arginase in microvascular endothelial cells counteracts nitric oxide-mediated vasodilatory function. Faseb J 15(7): 1264-1266.
11. Tiefenbacher CP, Chilian WM, Mitchell M, DeFily DV, (1996) Restoration of endothelium-dependent vasodilation after reperfusion injury by tetrahydrobiopterin. Circulation 94(6): 1423-1429.
12. Qamirani E, Ren Y, Kuo L, Hein TW, (2005) C-reactive protein inhibits endothelium-dependent NO-mediated dilation in coronary arterioles by activating p38 kinase and NAD(P)H oxidase. Arterioscler Thromb Vasc Biol 25(5): 995-1001.
13. Yabanoglu S, Akkiki M, Seguelas MH, Mialet-Perez J, Parini A, et al. (2009) Platelet derived serotonin drives the activation of rat cardiac fibroblasts by 5-HT2A receptors. J Mol Cell Cardiol 46(4): 518-525.
14. Villeneuve C, Caudrillier A, Ordener C, Pizzinat N, Parini A, et al. (2009) Dose-dependent activation of distinct hypertrophic pathways by serotonin in cardiac cells. Am J Physiol Heart Circ Physiol 297(2): H821-828.
15. Ishida T, Kawashima S, Hirata K, Yokoyama M, (1998) Nitric oxide is produced via 5-HT1B and 5-HT2B receptor activation in human coronary artery endothelial cells. Kobe J Med Sci 44(2): 51-63.
16. Sole MJ, Shum A, Van Loon GR, (1979) Serotonin metabolism in the normal and failing hamster heart. Circ Res 45(5): 629-634.
17. Wei JF, Wei XL, Mo YZ, He SH, (2009) Induction of mast cell accumulation, histamine release and skin edema by N49 phospholipase A2. BMC Immunol 10: 21.
18. Cote F, Thevenot E, Fligny C, Fromes Y, Darmon M, et al. (2003) Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function. Proc Natl Acad Sci U S A 100(23): 13525-13530.
19. Izikki M, Hanoun N, Marcos E, Savale L, Barlier-Mur AM, et al. (2007) Tryptophan hydroxylase 1 knockout and tryptophan hydroxylase 2 polymorphism: effects on hypoxic pulmonary hypertension in mice. Am J Physiol Lung Cell Mol Physiol 293(4): L1045-1052.
20. Gersch C, Dewald O, Zoerlein M, Michael LH, Entman ML, et al. (2002) Mast cells and macrophages in normal C57/BL/6 mice. Histochem Cell Biol 118(1): 41-49.
21. Manjarrez-Gutierrez G, Camacho-Calderon N, Mercado-Camargo R, Boyzo-Montes de Oca A, Arvizu-Flores A, et al. (2009) Characterization of serotonergic cells in fetal heart tissue. Cir Cir 77(6): 395-400.
22. Mekontso-Dessap A, Brouri F, Pascal O, Lechat P, Hanoun N, et al. (2006) Deficiency of the 5-hydroxytryptamine transporter gene leads to cardiac fibrosis and valvulopathy in mice. Circulation 113(1): 81-89.
23. Mount PF, Kemp BE, Power DA, (2007) Regulation of endothelial and myocardial NO synthesis by multi-site eNOS phosphorylation. J Mol Cell Cardiol 42(2): 271-279.
24. Lopez de Pablo AL, Moreno MJ, Marco EJ, (1996) In vivo tryptophan hydroxylase activity in rat major cerebral arteries is decreased by dorsal raphe nucleus lesions. J Neurochem 67(5): 2060-2065.
25. Nomura T, Inoue K, Creveling CR, Komatsu F, Ohta N, et al. (1996) Immunocytochemical localization of aromatic L-amino acid decarboxylase and catechol-O-methyltransferase in blood vessel wall of the human dental pulp. Brain Res 735(2): 314-316.
26. Eddahibi S, Guignabert C, Barlier-Mur AM, Dewachter L, Fadel E, et al. (2006) Cross talk between endothelial and smooth muscle cells in pulmonary hypertension: critical role for serotonin-induced smooth muscle hyperplasia. Circulation 113(15): 1857-1864.
27. Ni W, Geddes TJ, Priestley JR, Szasz T, Kuhn DM, et al. (2008) The existence of a local 5-hydroxytryptaminergic system in peripheral arteries. Br J Pharmacol 154(3): 663-674.
28. Houston DS, Vanhoutte PM, (1988) Comparison of serotonergic receptor subtypes on the smooth muscle and endothelium of the canine coronary artery. J Pharmacol Exp Ther 244(1): 1-10.
29. Cocks TM, Arnold PJ, (1992) 5-Hydroxytryptamine (5-HT) mediates potent relaxation in the sheep isolated pulmonary vein via activation of 5-HT4 receptors. Br J Pharmacol 107(2): 591-596.
30. Hein TW, Zhang C, Wang W, Chang CI, Thengchaisri N, et al. (2003) Ischemia-reperfusion selectively impairs nitric oxide-mediated dilation in coronary arterioles: counteracting role of arginase. Faseb J 17(15): 2328-2330.
31. Asada M, Ebihara S, Yamanda S, Niu K, Okazaki T, et al. (2009) Depletion of serotonin and selective inhibition of 2B receptor suppressed tumor angiogenesis by inhibiting endothelial nitric oxide synthase and extracellular signal-regulated kinase 1/2 phosphorylation. Neoplasia 11(4): 408-417.