mdv1-miR-M7-5p, located in the newly identified first intron of the latency-associated transcript of Marek's disease virus, targets the immediate-early genes ICP4 and ICP27

Journal of General Virology

Volumn 93, Issue 8, 2012, Pages 1731-1742

  Strassheim, S ^a   Stik, G ^a   Rasschaert, D ^a   Laurent, S ^a,b  

^a UNIVERSITÉ DE TOURS   (France)

^b CEMAGREF   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; ICP27 PROTEIN; ICP4 PROTEIN; LATENCY ASSOCIATED TRANSCRIPT; MICRORNA; UNCLASSIFIED DRUG; UNTRANSLATED RNA;

3' UNTRANSLATED REGION; ARTICLE; DNA SEQUENCE; GENE TARGETING; IN VITRO STUDY; INTRON; MARDIVIRUS; MAREK DISEASE; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIRUS LATENCY; VIRUS REACTIVATION;

ALTERNATIVE SPLICING; ANIMALS; BASE SEQUENCE; BIRDS; CELL LINE; FIBROBLASTS; GENE EXPRESSION REGULATION, VIRAL; GENES, IMMEDIATE-EARLY; HERPESVIRUS 2, GALLID; MICRORNAS; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS, GENETIC; RNA, VIRAL; VIRAL PROTEINS; VIRUS LATENCY;

GALLID HERPESVIRUS 2; GALLUS GALLUS;

EID: 84864050799     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.043109-0     Document Type: Article

References (47)

1. Akiyama, Y., Kato, S. & Iwa, N. (1973). Continuous cell culture from lymphoma of Marek's disease. Biken J 16, 177-179.
2. Amor, S., Strassheim, S., Dambrine, G., Remy, S., Rasschaert, D. & Laurent, S. (2011). ICP27 protein of Marek's disease virus interacts with SR proteins and inhibits the splicing of cellular telomerase chTERT and viral vIL8 transcripts. J Gen Virol 92, 1273-1278.
3. Anselmo, A., Flori, L., Jaffrezic, F., Rutigliano, T., Cecere, M., Cortes-Perez, N., Lefevre, F., Rogel-Gaillard, C. & Giuffra, E. (2011). Coexpression of host and viral microRNAs in porcine dendritic cells infected by the pseudorabies virus. PLoS ONE 6, e17374.
4. Baigent, S. J. & Davison, F. (2004). Marek's disease virus: biology and life cycle. In Marek's Disease: an Evolving Problem, pp. 62-77. Edited by F. Davison & V. Nair. Oxford: Elsevier Academic Press.
5. Bellare, P. & Ganem, D. (2009). Regulation of KSHV lytic switch protein expression by a virus-encoded microRNA: an evolutionary adaptation that fine-tunes lytic reactivation. Cell Host Microbe 6, 570-575.
6. Boss, I. W., Plaisance, K. B. & Renne, R. (2009). Role of virusencoded microRNAs in herpesvirus biology. Trends Microbiol 17, 544-553.
7. Burnside, J. & Morgan, R. W. (2007). Genomics and Marek's disease virus. Cytogenet Genome Res 117, 376-387.
8. Burnside, J., Bernberg, E., Anderson, A., Lu, C., Meyers, B. C., Green, P. J., Jain, N., Isaacs, G. & Morgan, R. W. (2006). Marek's disease virus encodes microRNAs that map to meq and the latency-associated transcript. J Virol 80, 8778-8786.
9. Cai, X. & Cullen, B. R. (2006). Transcriptional origin of Kaposi's sarcoma-associated herpesvirus microRNAs. J Virol 80, 2234-2242.
10. Cai, X., Lu, S., Zhang, Z., Gonzalez, C. M., Damania, B. & Cullen, B. R. (2005). Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells. Proc Natl Acad Sci U S A 102, 5570-5575.
11. Cantello, J. L., Anderson, A. S. & Morgan, R. W. (1994). Identification of latency-associated transcripts that map antisense to the ICP4 homolog gene of Marek's disease virus. J Virol 68, 6280-6290.
12. Cantello, J. L., Parcells, M. S., Anderson, A. S. & Morgan, R. W. (1997). Marek's disease virus latency-associated transcripts belong to a family of spliced RNAs that are antisense to the ICP4 homolog gene. J Virol 71, 1353-1361.
13. Chi, S. W., Zang, J. B., Mele, A. & Darnell, R. B. (2009). Argonaute HITSCLIP decodesmicroRNA-mRNA interactionmaps. Nature 460, 479-486.
14. Cui, C., Griffiths, A., Li, G., Silva, L. M., Kramer, M. F., Gaasterland, T., Wang, X. J. & Coen, D. M. (2006). Prediction and identification of herpes simplex virus 1-encoded microRNAs. J Virol 80, 5499-5508.
15. Fragnet, L., Kut, E. & Rasschaert, D. (2005). Comparative functional study of the viral telomerase RNA based on natural mutations. J Biol Chem 280, 23502-23515.
16. Grey, F., Meyers, H., White, E. A., Spector, D. H. & Nelson, J. (2007). A human cytomegalovirus-encoded microRNA regulates expression of multiple viral genes involved in replication. PLoS Pathog 3, e163.
17. Grundhoff, A., Sullivan, C. S. & Ganem, D. (2006). A combined computational and microarray-based approach identifies novel microRNAs encoded by human gamma-herpesviruses. RNA 12, 733-750.
18. Iizasa, H., Wulff, B. E., Alla, N. R., Maragkakis, M., Megraw, M., Hatzigeorgiou, A., Iwakiri, D., Takada, K., Wiedmer, A. & other authors (2010). Editing of Epstein-Barr virus-encoded BART6 microRNAs controls their Dicer targeting and consequently affects viral latency. J Biol Chem 285, 33358-33370.
19. Jurak, I., Kramer, M. F., Mellor, J. C., van Lint, A. L., Roth, F.P., Knipe, D. M. & Coen, D. M. (2010). Numerous conserved and divergent microRNAs expressed by herpes simplex viruses 1 and 2. J Virol 84, 4659-4672.
20. Kato, K., Izumiya, Y., Tohya, Y., Takahashi, E., Hirai, K. & Kawaguchi, Y. (2002). Identification and characterization of Marek's disease virus serotype 1 (MDV1) ICP22 gene product: MDV1 ICP22 transactivates the MDV1 ICP27 promoter synergistically with MDV1 ICP4. Vet Microbiol 85, 305-313.
21. Kim, Y. K. & Kim, V. N. (2007). Processing of intronic microRNAs. EMBO J 26, 775-783.
22. Krol, J., Loedige, I. & Filipowicz, W. (2010). The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet 11, 597-610.
23. Lagos-Quintana, M., Rauhut, R., Lendeckel, W. & Tuschl, T. (2001). Identification of novel genes coding for small expressed RNAs. Science 294, 853-858.
24. Li, D. S., Pastorek, J., Zelni{dotless}́k, V., Smith, G. D. & Ross, L. J. (1994). Identification of novel transcripts complementary to the Marek's disease virus homologue of the ICP4 gene of herpes simplex virus. J Gen Virol 75, 1713-1722.
25. Li, D., O'Sullivan, G., Greenall, L., Smith, G., Jiang, C. & Ross, N. (1998). Further characterization of the latency-associated transcription unit of Marek's disease virus. Arch Virol 143, 295-311.
26. Lin, H. R. & Ganem, D. (2011). Viral microRNA target allows insight into the role of translation in governing microRNA target accessibility. Proc Natl Acad Sci U S A 108, 5148-5153.
27. Lu, C. C., Li, Z., Chu, C. Y., Feng, J., Feng, J., Sun, R. & Rana, T. M. (2010). MicroRNAs encoded by Kaposi's sarcoma-associated herpesvirus regulate viral life cycle. EMBO Rep 11, 784-790.
28. McKie, E. A., Ubukata, E., Hasegawa, S., Zhang, S., Nonoyama, M. & Tanaka, A. (1995). The transcripts from the sequences flanking the short component of Marek's disease virus during latent infection form a unique family of 39-coterminal RNAs. J Virol 69, 1310-1314.
29. Murphy, E., Vani{dotless}́cek, J., Robins, H., Shenk, T. & Levine, A. J. (2008). Suppression of immediate-early viral gene expression by herpesviruscoded microRNAs: implications for latency. Proc Natl Acad Sci U S A 105, 5453-5458.
30. Muylkens, B., Coupeau, D., Dambrine, G., Trapp, S. & Rasschaert, D. (2010). Marek's disease virus microRNA designated Mdv1-pre-miRM4 targets both cellular and viral genes. Arch Virol 155, 1823-1837.
31. Olena, A. F. & Patton, J. G. (2010). Genomic organization of microRNAs. J Cell Physiol 222, 540-545.
32. Petherbridge, L., Brown, A. C., Baigent, S. J., Howes, K., Sacco, M. A., Osterrieder, N. & Nair, V. K. (2004). Oncogenicity of virulent Marek's disease virus cloned as bacterial artificial chromosomes. J Virol 78, 13376-13380.
33. Pfeffer, S., Zavolan, M., Grä sser, F. A., Chien, M., Russo, J. J., Ju, J., John, B., Enright, A. J., Marks, D. & other authors (2004). Identification of virus-encoded microRNAs. Science 304, 734-736.
34. Pfeffer, S., Sewer, A., Lagos-Quintana, M., Sheridan, R., Sander, C., Grä sser, F. A., van Dyk, L. F., Ho, C. K., Shuman, S. & other authors (2005). Identification of microRNAs of the herpesvirus family. Nat Methods 2, 269-276.
35. Pratt, W. D., Cantello, J., Morgan, R. W. & Schat, K. A. (1994). Enhanced expression of the Marek's disease virus-specific phosphoproteins after stable transfection of MSB-1 cells with the Marek's disease virus homologue of ICP4. Virology 201, 132-136.
36. Preston, K. J. & Garland, A. J. (1979). In vivo and in vitro studies on temperature-sensitive mutants of swine vesicular disease virus. J Hyg (Lond) 83, 319-330.
37. Raymond, C. K., Roberts, B. S., Garrett-Engele, P., Lim, L. P. & Johnson, J. M. (2005). Simple, quantitative primer-extension PCR assay for direct monitoring of microRNAs and short-interfering RNAs. RNA 11, 1737-1744.
38. Schat, K. A. & Nair, V. (2008). Marek's disease. In Diseases of Poultry, pp. 452-514. Edited by Y. M. Saif. Oxford: Wiley-Blackwell.
39. Smith, R. W., Malik, P. & Clements, J. B. (2005). The herpes simplex virus ICP27 protein: a multifunctional post-transcriptional regulator of gene expression. Biochem Soc Trans 33, 499-501.
40. Stik, G., Laurent, S., Coupeau, D., Coutaud, B., Dambrine, G., Rasschaert, D. & Muylkens, B. (2010). A p53-dependent promoter associated with polymorphic tandem repeats controls the expression of a viral transcript encoding clustered microRNAs. RNA 16, 2263-2276.
41. Sullivan, C. S., Grundhoff, A. T., Tevethia, S., Pipas, J. M. & Ganem, D. (2005). SV40-encoded microRNAs regulate viral gene expression and reduce susceptibility to cytotoxic T cells. Nature 435, 682-686.
42. Tang, S., Patel, A. & Krause, P. R. (2009). Novel less-abundant viral microRNAs encoded by herpes simplex virus 2 latency-associated transcript and their roles in regulating ICP34.5 and ICP0 mRNAs. J Virol 83, 1433-1442.
43. Tay, Y., Zhang, J., Thomson, A. M., Lim, B. & Rigoutsos, I. (2008). MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation. Nature 455, 1124-1128.
44. Tulman, E. R., Afonso, C. L., Lu, Z., Zsak, L., Rock, D. L. & Kutish, G. F. (2000). The genome of a very virulent Marek's disease virus. J Virol 74, 7980-7988.
45. Umbach, J. L., Kramer, M. F., Jurak, I., Karnowski, H. W., Coen, D. M. & Cullen, B. R. (2008). MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs. Nature 454, 780-783.
46. Waidner, L. A., Burnside, J., Anderson, A. S., Bernberg, E. L., German, M. A., Meyers, B. C., Green, P. J. & Morgan, R. W. (2011). A microRNA of infectious laryngotracheitis virus can downregulate and direct cleavage of ICP4 mRNA. Virology 411, 25-31.
47. Yao, Y., Zhao, Y., Xu, H., Smith, L. P., Lawrie, C. H., Watson, M. & Nair, V. (2008). MicroRNA profile of Marek's disease virus-transformed T-cell line MSB-1: predominance of virus-encoded microRNAs. J Virol 82, 4007-4015.