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ChemBioChem

Volumn 13, Issue 11, 2012, Pages 1645-1651

Substrate-Induced Conformational Change and Isomerase Activity of Dienelactone Hydrolase and its Site-Specific Mutants

(4) Walker, Ian a Hennessy, James E a Ollis, David L a Easton, Christopher J a

a AUSTRALIAN NATIONAL UNIVERSITY (Australia)

Author keywords

Enzyme catalysis; Hydrolases; Isomerases; Kinetics; Mutagenesis

Indexed keywords

ARGININE; CARBOXYLIC ACID; CARBOXYMETHYLENEBUTENOLIDASE; CYSTEINE; DIENELACTONE; HYDROLASE; ISOMERASE; LACTONE; MUTANT PROTEIN; SERINE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL INTERACTION; CONFORMATIONAL TRANSITION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME CONFORMATION; ENZYME INACTIVATION; ENZYME KINETICS; HYDROLYSIS; ISOMERIZATION; PRIORITY JOURNAL;

BIOCATALYSIS; CARBOXYLIC ESTER HYDROLASES; CATALYTIC DOMAIN; HYDROLYSIS; LACTONES; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN CONFORMATION; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

EID: 84864016329 PISSN: 14394227 EISSN: 14397633 Source Type: Journal
DOI: 10.1002/cbic.201200232 Document Type: Article

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