Intra-islet proliferation of cytotoxic T lymphocytes contributes to insulitis progression

European Journal of Immunology

Volumn 42, Issue 7, 2012, Pages 1717-1722

  Graham, Kate L ^a   Krishnamurthy, Balasubramanian ^a   Fynch, Stacey ^a   Ayala Perez, Rochelle ^a   Slattery, Robyn M ^b   Santamaria, Pere ^c   Thomas, Helen E ^d   Kay, Thomas W H ^d  

^a ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c UNIVERSITY OF CALGARY   (Canada)

^d UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Beta cell; Cytotoxic T cells; Insulitis; MHC class I

Indexed keywords

FINGOLIMOD; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DISEASE COURSE; INHIBITION KINETICS; INSULITIS; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE;

ANIMALS; CELL PROLIFERATION; DIABETES MELLITUS, TYPE 1; DISEASE PROGRESSION; FLOW CYTOMETRY; HISTOCOMPATIBILITY ANTIGENS CLASS I; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE AGENTS; ISLETS OF LANGERHANS; MICE; MICE, INBRED NOD; MICE, TRANSGENIC; PROPYLENE GLYCOLS; RECEPTORS, ANTIGEN, T-CELL; SPHINGOSINE; T-LYMPHOCYTES, CYTOTOXIC;

EID: 84864008955     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201242435     Document Type: Article

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