Mercury in the Spinal Cord After Inhalation of Mercury

Basic and Clinical Pharmacology and Toxicology

Volumn 111, Issue 2, 2012, Pages 126-132

  Roos, Per M ^a,b   Dencker, Lennart ^c  

^a KAROLINSKA INSTITUTE   (Sweden)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

MERCURY;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTERIOR HORN CELL; ARTICLE; AUTOMETALLOGRAPHY; AUTORADIOGRAPHY; BRAIN STEM; BREATHING; CEREBELLUM; CONTROLLED STUDY; DEGENERATIVE DISEASE; EXPERIMENTAL MONKEY; EXPOSURE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPINAL CORD; TISSUE LEVEL;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ANTERIOR HORN CELLS; AUTORADIOGRAPHY; CALLITHRIX; DOSE-RESPONSE RELATIONSHIP, DRUG; HALF-LIFE; INHALATION EXPOSURE; MALE; MERCURY; METALLOTHIONEIN; MICE; MICE, 129 STRAIN; SPINAL CORD;

CALLITHRIX JACCHUS; MARMOSETS; PRIMATES; RODENTIA;

EID: 84864006271     PISSN: 17427835     EISSN: 17427843     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2012.00872.x     Document Type: Article

References (48)

1. Lilienfeld DE, Perl DP. Projected neurodegenerative disease mortality in the United States, 1990-2040. Neuroepidemiology 1993;12:219-28.
2. Perry JJ, Shin DS, Tainer JA. Amyotrophic lateral sclerosis. Adv Exp Med Biol 2010;685:9-20.
3. Hofer A, Gasser T. New aspects of genetic contributions to Parkinson's disease. J Mol Neurosci 2004;24:417-24.
4. Bettens K, Sleegers K, Van Broeckhoven C. Current status on Alzheimer disease molecular genetics: from past, to present, to future. Hum Mol Genet 2010;19:R4-11.
5. Maslow K. Alzheimer's disease facts and figures. Alzheimers Dement 2010;6:158-94.
6. Lilienfeld DE, Chan E, Ehland J, Godbold J, Landrigan PJ, Marsh G et al. Two decades of increasing mortality from Parkinson's disease among the US elderly. Arch Neurol 1990;47:731-4.
7. Fang F, Valdimarsdottir U, Bellocco R, Ronnevi LO, Sparen P, Fall K et al. Amyotrophic lateral sclerosis in Sweden, 1991-2005. Arch Neurol 2009;66:515-9.
8. Mitchell JD. Amyotrophic lateral sclerosis: toxins and environment. Amyotroph Lateral Scler Other Motor Neuron Disord 2000;1:235-50.
9. Roos PM, Vesterberg O, Nordberg M. Metals in motor neuron diseases. Exp Biol Med (Maywood) 2006;231:1481-7.
10. Hirano A. Cytopathology of amyotrophic lateral sclerosis: a personal perspective of recent developments. Neuropathology 2007;15:1-6.
11. Praline J, Guennoc AM, Limousin N, Hallak H, de Toffol B, Corcia P. ALS and mercury intoxication: a relationship? Clin Neurol Neurosurg 2007;109:880-3.
12. Kantarjian AD. A syndrome clinically resembling amyotrophic lateral sclerosis following chronic mercurialism. Neurology 1961;11:639-44.
13. Clarkson TW, Magos L. The toxicology of mercury and its chemical compounds. Crit Rev Toxicol 2006;36:609-62.
14. Arvidson B. Inorganic mercury is transported from muscular nerve terminals to spinal and brainstem motoneurons. Muscle Nerve 1992;15:1089-94.
15. Larsson B, Ullberg S. Whole-body autoradiography. J Histochem Cytochem 1981;29:216-25.
16. Khayat A, Dencker L. Organ and cellular distribution of inhaled metallic mercury in the rat and Marmoset monkey (Callithrix jacchus): influence of ethyl alcohol pretreatment. Acta Pharmacol Toxicol (Copenh) 1984;55:145-52.
17. Stankovic R. Atrophy of large myelinated motor axons and declining muscle grip strength following mercury vapor inhalation in mice. Inhal Toxicol 2006;18:57-69.
18. Danscher G, Schroder HD. Histochemical demonstration of mercury induced changes in rat neurons. Histochemistry 1979;60:1-7.
19. Ochs S, Jersild RA Jr, Pourmand R, Potter CG. The beaded form of myelinated nerve fibers. Neuroscience 1994;61:361-72.
20. Tjalve H, Henriksson J. Uptake of metals in the brain via olfactory pathways. Neurotoxicology 1999;20:181-95.
21. Nierenberg DW, Nordgren RE, Chang MB, Siegler RW, Blayney MB, Hochberg F et al. Delayed cerebellar disease and death after accidental exposure to dimethylmercury. N Engl J Med 1998;338:1672-6.
22. Berlin M, Fazackerley J, Nordberg G. The uptake of mercury in the brains of mammals exposed to mercury vapor and to mercuric salts. Arch Environ Health 1969;18:719-29.
23. Bjorkman L, Svartengren M, Nordberg M. Individual differences in activity of glutathione peroxidase and catalase studied in monozygotic twins discordant for smoking. Hum Exp Toxicol 1992;11:341-6.
24. Berlin M, Zalups RK, Fowler BA. Mercury. In: Nordberg GF, Fowler FB, Nordberg M, Friberg LT (eds). Handbook on the Toxicology of Metals 3rd edition. Elsevier Publisher, 2007; 675-729.
25. Risher JF, Murray HE, Prince GR. Organic mercury compounds: human exposure and its relevance to public health. Toxicol Ind Health 2002;18:109-60.
26. Zheng W, Perry DF, Nelson DL, Aposhian HV. Choroid plexus protects cerebrospinal fluid against toxic metals. FASEB J 1991;5:2188-93.
27. Yokel RA. Blood-brain barrier flux of aluminum, manganese, iron and other metals suspected to contribute to metal-induced neurodegeneration. J Alzheimers Dis 2006;10:223-53.
28. Zheng W, Aschner M, Ghersi-Egea JF. Brain barrier systems: a new frontier in metal neurotoxicological research. Toxicol Appl Pharmacol 2003;192:1-11.
29. Stankovic RK, Lee V, Kekic M, Harper C. The expression and significance of metallothioneins in murine organs and tissues following mercury vapour exposure. Toxicol Pathol 2003;31:514-23.
30. Taylor MD, Erikson KM, Dobson AW, Fitsanakis VA, Dorman DC, Aschner M. Effects of inhaled manganese on biomarkers of oxidative stress in the rat brain. Neurotoxicology 2006;27:788-97.
31. Pamphlett R, Coote P. Entry of low doses of mercury vapor into the nervous system. Neurotoxicology 1998;19:39-47.
32. 3) vapors in the brain of rats and mice. J Neuropathol Exp Neurol 1969;28:308-20.
33. AFS. Arbetsmiljoverkets forfattningssamling. Hygieniska gransvarden och atgarder mot luftfororeningar. Arbetsmiljoverket, Stockholm, 2010. AFS 2010:13.
34. Risher JF, De Rosa CT. Inorganic: the other mercury. J Environ Health 2007;70:9-16; discussion 40.
35. de Carvalho M, Swash M. Nerve conduction studies in amyotrophic lateral sclerosis. Muscle Nerve 2000;23:344-52.
36. Moller-Madsen B. Localization of mercury in CNS of the rat. V. Inhalation exposure to metallic mercury. Arch Toxicol 1992;66:79-89.
37. Danscher G, Moller-Madsen B. Silver amplification of mercury sulfide and selenide: a histochemical method for light and electron microscopic localization of mercury in tissue. J Histochem Cytochem 1985;33:219-28.
38. Shanker G, Syversen T, Aschner JL, Aschner M. Modulatory effect of glutathione status and antioxidants on methylmercury-induced free radical formation in primary cultures of cerebral astrocytes. Brain Res Mol Brain Res 2005;137:11-22.
39. Kramer KK, Liu J, Choudhuri S, Klaassen CD. Induction of metallothionein mRNA and protein in murine astrocyte cultures. Toxicol Appl Pharmacol 1996;136:94-100.
40. Kramer KK, Zoelle JT, Klaassen CD. Induction of metallothionein mRNA and protein in primary murine neuron cultures. Toxicol Appl Pharmacol 1996;141:1-7.
41. Nordberg M. Metallothioneins: historical review and state of knowledge. Talanta 1998;46:243-54.
42. Stankovic RK. Atrophy of large myelinated axons in metallothionein-I, II knockout mice. Cell Mol Neurobiol 2005;25:943-53.
43. Sillevis Smitt PA, Blaauwgeers HG, Troost D, de Jong JM. Metallothionein immunoreactivity is increased in the spinal cord of patients with amyotrophic lateral sclerosis. Neurosci Lett 1992;144:107-10.
44. West AK, Hidalgo J, Eddins D, Levin ED, Aschner M. Metallothionein in the central nervous system: roles in protection, regeneration and cognition. Neurotoxicology 2008;29:489-503.
45. Brown DR. Metalloproteins and neuronal death. Metallomics 2009;2:186-94.
46. Adams CR, Ziegler DK, Lin JT. Mercury intoxication simulating amyotrophic lateral sclerosis. JAMA 1983;250:642-3.
47. Marins RV, de Andrade JB, Pereira PA, Paiva EC, Paraquetti HH. Sampling techniques for the assessment of anthropogenic vapour and particulate mercury in the Brazilian Amazon atmosphere. J Environ Monit 2000;2:325-8.
48. Barber TE. Inorganic mercury intoxication reminiscent of amyotrophic lateral sclerosis. J Occup Med 1978;20:667-9.