Extra copies of ALK gene locus is a recurrent genetic aberration and favorable prognostic factor in both ALK-positive and ALK-negative anaplastic large cell lymphomas

Leukemia Research

Volumn 36, Issue 9, 2012, Pages 1141-1146

  Yu, Ran ^a,b   Chen, Gang ^c   Zhou, Chunju ^d   Gao, Zifen ^e   Shi, Yunfei ^e   Shi, Yan ^f   Zhou, Xiaoge ^g   Xie, Jianlan ^g   Liu, Hongxiang ^h   Gong, Liping ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b Weifang Nursing Vocational College   (China)

^c FUJIAN PROVINCIAL TUMOR HOSPITAL   (China)

^d CAPITAL MEDICAL UNIVERSITY   (China)

^e PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^f HARBIN MEDICAL UNIVERSITY   (China)

^g CAPITAL MEDICAL UNIVERSITY   (China)

^h UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Anaplastic large cell lymphoma (ALCL); Anaplastic lymphoma kinase (ALK); Fluorescence in situ hybridization (FISH); Molecular genetics

Indexed keywords

ACTIVIN RECEPTOR LIKE KINASE; ANTHRACYCLINE; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ALK GENE; ARTICLE; CANCER PATIENT; CANCER PROGNOSIS; CANCER SURVIVAL; CHILD; CHROMOSOME 10; CHROMOSOME 2; CHROMOSOME ABERRATION; CONTROLLED STUDY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; FOLLOW UP; GENE ACTIVITY; GENE EXPRESSION; GENE FUNCTION; GENE LOCUS; GENE NUMBER; GENE STRUCTURE; GENETIC ANALYSIS; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LARGE CELL LYMPHOMA; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; ONCOGENE; OUTCOME ASSESSMENT; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD;

ADOLESCENT; ADULT; AGED; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; DNA COPY NUMBER VARIATIONS; FEMALE; GENE DOSAGE; GENE FREQUENCY; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INFANT; LYMPHOMA, LARGE-CELL, ANAPLASTIC; MALE; MIDDLE AGED; PROGNOSIS; RECEPTOR PROTEIN-TYROSINE KINASES; YOUNG ADULT;

EID: 84864004888     PISSN: 01452126     EISSN: 18735835     Source Type: Journal    
DOI: 10.1016/j.leukres.2012.06.005     Document Type: Article

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