Effects of manipulating apoptosis on sindbis virus infection of Aedes aegypti mosquitoes

Journal of Virology

Volumn 86, Issue 12, 2012, Pages 6546-6554

  Wang, Hua ^a,b   Gort, Taryn ^a,c   Boyle, Daniel L ^a   Clem, Rollie J ^a  

^a KANSAS STATE UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; DOUBLE STRANDED RNA;

AEDES AEGYPTI; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRONC GENE; ENZYME ACTIVITY; ENZYME ASSAY; FEMALE; GENE; GENE EXPRESSION REGULATION; GENE SILENCING; IAP1 GENE; INNATE IMMUNITY; INTESTINE EPITHELIUM; INTESTINE INFECTION; MIDGUT; MOLECULAR DYNAMICS; MORTALITY; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINDBIS VIRUS; TOGAVIRUS INFECTION; TRANSMISSION ELECTRON MICROSCOPY; VECTOR CONTROL; VIRUS REPLICATION;

AEDES; ANIMALS; APOPTOSIS; GENE SILENCING; INSECT PROTEINS; INSECT VECTORS; SINDBIS VIRUS; VIRUS REPLICATION;

AEDES AEGYPTI; ARBOVIRUS; HEXAPODA; MAMMALIA; SINDBIS VIRUS;

EID: 84864003887     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00125-12     Document Type: Article

References (44)

1. Black WCI, et al. 2002. Flavivirus susceptibility in Aedes aegypti. Arch. Med. Res. 33:379 -388.
2. Bowers DF, Coleman CG, Brown DT. 2003. Sindbis virus-associated pathology in Aedes albopictus (Diptera: Culicidae). J. Med. Entomol. 40: 698-705.
3. Bryant B, Blair CD, Olson KE, Clem RJ. 2008. Annotation and expression profiling of apoptosis-related genes in the yellow fever mosquito, Aedes aegypti. Insect Biochem. Mol. Biol. 38:331-345.
4. Campbell CL, et al. 2008. Aedes aegypti uses RNA interference in defense against Sindbis virus infection. BMC Microbiol. 8:47. doi:10.1186/1471-2180-8-47.
5. Cirimotich CM, Scott JC, Phillips AT, Geiss BJ, Olson KE. 2009. Suppression of RNA interference increases alphavirus replication and virus-associated mortality in Aedes aegypti mosquitoes. BMC Microbiol. 9:49. doi:10.1186/1471-2180-9-49.
6. Clarke TE, Clem RJ. 2003. Insect defenses against virus infection: the role of apoptosis. Int. Rev. Immunol. 22:401- 424.
7. Daish TJ, Mills K, Kumar S. 2004. Drosophila caspase DRONC is required for specific developmental cell death pathways and stress-induced apoptosis. Dev. Cell 7:909 -915.
8. Foy BD, et al. 2004. Development of a new Sindbis virus transducing system and its characterization in three culicine mosquitoes and two lepidopteran species. Insect Mol. Biol. 13:89 -100.
9. Fragkoudis R, Attarzadeh-Yazdi G, Nash AA, Fazakerley JK, Kohl A. 2009. Advances in dissecting mosquito innate immune responses to arbovirus infection. J. Gen. Virol. 90:2061-2072.
10. Franz AW, et al. 2006. Engineering RNA interference-based resistance to dengue virus type 2 in genetically modified Aedes aegypti. Proc. Natl. Acad. Sci. U. S. A. 103:4198-4203.
11. Girard YA, Popov V, Wen J, Han V, Higgs S. 2005. Ultrastructural study of West Nile virus pathogenesis in Culex pipiens quinquefasciatus (Diptera: Culicidae). J. Med. Entomol. 42:429-444.
12. Girard YA, et al. 2007. Salivary gland morphology and virus transmission during long-term cytopathologic West Nile virus infection in Culex mosquitoes. Am. J. Trop. Med. Hyg. 76:118 -128.
13. Hubalek Z. 2008. Mosquito-borne viruses in Europe. Parasitol. Res. 103: S29 -S43.
14. Karpf AR, Brown DT. 1998. Comparison of Sindbis virus-induced pathology in mosquito and vertebrate cell cultures. Virology 240:193-201.
15. Keene KM, et al. 2004. RNA interference acts as a natural antiviral response to o'nyong-nyong virus (Alphavirus; Togaviridae) infection of Anopheles gambiae mosquitoes. Proc. Natl. Acad. Sci. U. S. A. 101:17240- 17245.
16. Liu Q, Clem RJ. 2011. Defining the core apoptosis pathway in the mosquito disease vector Aedes aegypti: the roles of iap1, ark, dronc, and effector caspases. Apoptosis 16:105-113.
17. Lumjuan N, et al. 2011. The role of the Aedes aegypti Epsilon glutathione transferases in conferring resistance to DDT and pyrethroid insectides. Insect Biochem. Mol. Biol. 41:203-209.
18. McLean JE, Ruck A, Shirazian A, Pooyaei-Mehr F, Zakeri ZF. 2008. Viral manipulation of cell death. Curr. Pharm. Des. 14:198 -220.
19. Means JC, Passarelli AL. 2010. Viral fibroblast growth factor, matrix metalloproteases, and caspases are associated with enhancing systemic infection by baculoviruses. Proc. Natl. Acad. Sci. U. S. A. 107:9825-9830.
20. Mims CA, Day MF, Marshall ID. 1966. Cytopathic effect of Semliki Forest virus in the mosquito Aedes aegypti. Am. J. Trop. Med. Hyg. 15: 775-784.
21. Myles K, Pierro DJ, Olson KE. 2004. Comparison of the transmission potential of two genetically distinct Sindbis viruses after oral infection of Aedes aegypti (Diptera: Culicidae). J. Med. Entomol. 41:95-106.
22. Myles KM, Pierro DJ, Olson KE. 2003. Deletions in the putative cell receptor-binding domain of Sindbis virus strain MRE16 E2 glycoprotein reduce midgut infectivity in Aedes aegypti. J. Virol. 77:8872- 8881.
23. Pierro DJ, Myles KM, Foy BD, Beaty BJ, Olson KE. 2003. Development of an orally infectious Sindbis virus transducing system that efficiently disseminates and expresses green fluorescent protein in Aedes aegypti. Insect Mol. Biol. 12:107-116.
24. Pierro DJ, Powers EL, Olson KE. 2008. Genetic determinants of Sindbis virus mosquito infection are associated with a highly conserved alphavirus and flavivirus envelope sequence. J. Virol. 82:2966 -2974.
25. Pridgeon JW, Zhao L, Becnel JJ, Clark GG, Linthicum KJ. 2008. Developmental and environmental regulation of AaeIAP1 transcript in Aedes aegypti. J. Med. Entomol. 45:1071-1079.
26. Pridgeon JW, et al. 2008. Topically applied AeIAP1 double-stranded RNA kills female adults of Aedes aegypti. J. Med. Entomol. 45:414-420.
27. Ranson H, et al. 2011. Pyrethroid resistance in African anopheline mos-quitoes: what are the implications for malaria control? Trends Parasitol. 27:91-98.
28. Saleh M-C, et al. 2009. Antiviral immunity in Drosophila requires systemic RNA interference spread. Nature 458:346 -350.
29. Sanchez-Vargas I, et al. 2009. Dengue virus type 2 infections of Aedes aegypti are modulated by the mosquito's RNA interference pathway. PLoS Pathog. 5:e1000299. doi:10.1371/journal.ppat.1000299.
30. Sanders HR, et al. 2005. Sindbis virus induces transport processes and alters expression of innate immunity pathway genes in the midgut of the disease vector, Aedes aegypti. Insect Biochem. Mol. Biol. 35:1293-1307.
31. Sim C, et al. 2007. Anopheles gambiae heat shock cognate 70B impedes o'nyong-nyong virus replication. BMC Genomics 8:231. doi:10.1186/1471-2164-8-231.
32. Taylor RM, Hurlbut HS, Work TH, Kingston JR, Frothingham TE. 1955. Sindbis virus: a newly recognized arthropod-transmitted virus. Am. J. Trop. Med. Hyg. 4:844-862.
33. Vaidyanathan R, Scott TW. 2006. Apoptosis in mosquito midgut epithelia associated with West Nile virus infection. Apoptosis 11:1643-1651.
34. Waldhuber M, Emoto K, Petritsch C. 2005. The Drosophila caspase DRONC is required for metamorphosis and cell death in response to irradiation and developmental signals. Mech. Dev. 122:914 -927.
35. Wang H, Blair CD, Olson KE, Clem RJ. 2008. Effects of inducing or inhibiting apoptosis on Sindbis virus replication in mosquito cells. J. Gen. Virol. 89:2651-2661.
36. Wang H, Clem RJ. 2011. The role of IAP antagonist proteins in the core apoptosis pathway of the mosquito disease vector Aedes aegypti. Apoptosis 16:235-248.
37. Weaver SC, Lorenz LH, Scott TW. 1992. Pathologic changes in the midgut of Culex tarsalis following infection with Western equine encephalomyelitis virus. Am. J. Trop. Med. Hyg. 47:691-701.
38. Weaver SC, Scott TW, Lorenz LH, Lerdthusnee K, Romoser WS. 1988. Togavirus-associated pathologic changes in the midgut of a natural mosquito vector. J. Virol. 62:2083-2090.
39. WHO. 2007. Report of the scientific working group report on dengue, Geneva 1-5 October 2006. Dengue Bull. 31:183-186.
40. WHO. 2011. World malaria report 2011. World Health Organization, Geneva, Switzerland.
41. Xi Z, Ramirez JL, Dimopoulos G. 2008. The Aedes aegypti toll pathway controls dengue virus infection. PLoS Pathog. 4:e1000098. doi:10.1371/journal.ppat.1000098.
42. Xie W, Liang C, Birchler JA. 2011. Inhibition of RNA interference and modulation of transposable element expression by cell death in Drosophila. Genetics 188:823- 834.
43. Xu D, Li Y, Arcaro M, Lackey M, Bergmann A. 2005. The CARDcarrying caspase Dronc is essential for most, but not all, developmental cell death in Drosophila. Development 132:2125-2134.
44. Xu D, et al. 2009. Genetic control of programmed cell death (apoptosis) in Drosophila. Fly 3:78 -90.