Statistical analysis of glycosylation profiles to compare tissue type and inflammatory disease state

Bioinformatics

Volumn 28, Issue 13, 2012, Pages 1669-1676

  Hayes, Catherine A ^a   Nemes, Szilard ^b   Karlsson, Niclas G ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

MONOSACCHARIDE; OLIGOSACCHARIDE;

ARTICLE; CHEMISTRY; COLON; CYSTIC FIBROSIS; GLYCOBIOLOGY; GLYCOSYLATION; HUMAN; LIQUID CHROMATOGRAPHY; LUNG; MASS SPECTROMETRY; METABOLISM; METHODOLOGY; PROTEIN PROCESSING; STATISTICAL ANALYSIS; STATISTICAL MODEL; ULCERATIVE COLITIS;

CHROMATOGRAPHY, LIQUID; COLITIS, ULCERATIVE; COLON; CYSTIC FIBROSIS; DATA INTERPRETATION, STATISTICAL; GLYCOMICS; GLYCOSYLATION; HUMANS; LUNG; MASS SPECTROMETRY; MODELS, STATISTICAL; MONOSACCHARIDES; OLIGOSACCHARIDES; PROTEIN PROCESSING, POST-TRANSLATIONAL;

EID: 84864001286     PISSN: 13674803     EISSN: 14602059     Source Type: Journal    
DOI: 10.1093/bioinformatics/bts242     Document Type: Article

References (28)

1. Amerongen, A.V. et al. (1995) Salivary mucins: protective functions in relation to their diversity. Glycobiology, 5, 733-740.
2. An, H.J. and Lebrilla, C.B. (2010) Structure elucidation of native N- and O-linked glycans by tandem mass spectrometry (tutorial). Mass Spectrom. Rev., 30, 560-578.
3. Andersch-Bjorkman, Y. et al. (2007) Large scale identification of proteins, mucins, and their O-glycosylation in the endocervical mucus during the menstrual cycle. Mol. Cell Proteom., 6, 708-716.
4. Bikker, F.J. (2004) Salivary Agglutinin: Structure and Function. Vrije Universiteit Amsterdam, Amsterdam.
5. Bozdogan, H. (1987) Model selection and akaike information criterion (Aic): the general-theory and its analytical extensions. Psychometrika, 52, 345-370.
6. Campbell, M.P. et al. (2011) UniCarbKB: putting the pieces together for glycomics research. Proteomics, 11, 4117-4121.
7. Corfield, A.P. et al. (2000) Mucins and mucosal protection in the gastrointestinal tract: new prospects for mucins in the pathology of gastrointestinal disease. Gut, 47, 589-594.
8. Gill, D.J. et al. (2010) Location, location, location: new insights into O-GalNAc protein glycosylation. Trends Cell Biol., 21, 149-158.
9. Hayes, C.A. et al. (2011) UniCarb-DB: a database resource for glycomic discovery. Bioinformatics, 27, 1343-1344.
10. Hayes, C.A. et al. (2012) Glycomic work-flow for analysis of mucin O-linked oligosaccharides. Methods Mol. Biol., 842, 141-163.
11. Holmen, J.M. et al. (2004) Mucins and their O-Glycans from human bronchial epithelial cell cultures. Am. J. Physiol. Lung Cell Mol. Physiol., 287, L824-L834.
12. Karlsson, N.G. and Thomsson, K.A. (2009) Salivary MUC7 is a major carrier of blood group I type O-linked oligosaccharides serving as the scaffold for sialyl Lewis x. Glycobiology, 19, 288-300.
13. Larsson, J.M. et al. (2009)Acomplex, but uniform O-glycosylation of the human MUC2 mucin from colonic biopsies analyzed by nanoLC/MSn. Glycobiology, 19, 756-766.
14. Lauc, G. et al. (2010) Complex genetic regulation of protein glycosylation. Mol. Biosyst., 6, 329-335.
15. Marino, K. et al. (2010) A systematic approach to protein glycosylation analysis: a path through the maze. Nat. Chem. Biol., 6, 713-723.
16. Morelle, W. and Michalski, J.C. (2005) Glycomics and mass spectrometry. Curr. Pharm. Des., 11, 2615-2645.
17. Mortier, A. et al. (2011) Effect of posttranslational processing on the in vitro and in vivo activity of chemokines. Exp. Cell Res., 317, 642-654.
18. Novotny, M.V. et al. (2008) Biochemical individuality reflected in chromatographic, electrophoretic and mass-spectrometric profiles. J. Chromatogr. B Anal. Technol. Biomed. Life Sci., 866, 26-47.
19. Ohtsubo, K. and Marth, J.D. (2006) Glycosylation in cellular mechanisms of health and disease. Cell, 126, 855-867.
20. Packer, N.H. et al. (2008) Frontiers in glycomics: bioinformatics and biomarkers in disease. An NIH white paper prepared from discussions by the focus groups at a workshop on the NIH campus, Bethesda, MD(September 11-13, 2006). Proteomics, 8, 8-20.
21. Reis, C.A. et al. (2010) Alterations in glycosylation as biomarkers for cancer detection, J. Clin. Pathol., 63, 322-329.
22. Schulz, B.L. et al. (2007) Glycosylation of sputum mucins is altered in cystic fibrosis patients. Glycobiology, 17, 698-712.
23. Schulz, B.L. et al. (2005) Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions. Biochem. J., 387, 911-919.
24. Sidebotham, R.L. et al. (1995) Influence of blood group and secretor status on carbohydrate structures in human gastric mucins: implications for peptic ulcer. Clin. Sci. (London), 89, 405-415.
25. Thomsson, K.A. et al. (2005) MUC5B glycosylation in human saliva reflects blood group and secretor status. Glycobiology, 15, 791-804.
26. Vigerust, D.J. (2011) Protein glycosylation in infectious disease pathobiology and treatment. Cent. Eur. J. Biol., 6, 802-816.
27. Wine, J.J. and Joo, N.S. (2004) Submucosal glands and airway defense. Proc. Am. Thorac. Soc., 1, 47-53.
28. Wuhrer, M. et al. (2011) Mass spectrometric glycan rearrangements. Mass Spectrom. Rev., 30, 664-680.