Green tea extract markedly lowers the lymphatic absorption and increases the biliary secretion of 14C-benzo[a]pyrene in rats

Journal of Nutritional Biochemistry

Volumn 23, Issue 8, 2012, Pages 1007-1011

  Kim, Juyeon ^a   Koo, Sung I ^b   Noh, Sang K ^a  

^a Changwon National University   (South Korea)

^b UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

Tocopherol; Absorption; Benzo a pyrene; Bile; Green tea; Lipids; Lymph; Rats

Indexed keywords

14C BENZO[A]PYRENE; BENZO[A]PYRENE; GREEN TEA EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BILE; BILE SECRETION; CECUM; CONTROLLED STUDY; EXCRETION; INTESTINE ABSORPTION; LYMPH; MALE; NONHUMAN; RADIOACTIVITY; RAT; SMALL INTESTINE;

ABSORPTION; ANIMALS; BENZO(A)PYRENE; BILE; CARCINOGENS; LYMPH; MALE; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; TEA;

RATTUS;

EID: 84863999277     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2011.05.007     Document Type: Article

References (41)

1. Hennig B., Ettinger A.S., Jandacek R.J., Koo S., McClain C., Seifried H., et al. Using nutrition for intervention and prevention against environmental chemical toxicity and associated diseases. Environ Health Perspect 2007, 115:493-495.
2. Kazerouni N., Sinha R., Hsu C.H., Greenberg A., Rothman N. Analysis of 200 food items for benzo[a]pyrene and estimation of its intake in an epidemiologic study. Food Chem Toxicol 2001, 39:423-436.
3. Lawrence J.F., Weber D.F. Determination of polycyclic aromatic hydrocarbons in some Canadian commercial fish, shellfish, and meat products by liquid chromatography with confirmation by capillary gas chromatography-mass spectrometry. J Agric Food Chem 1984, 32:789-794.
4. Lawrence J.F., Weber D.F. Determination of polycyclic aromatic hydrocarbons in Canadian samples of processed vegetable and dairy products by liquid chromatography with fluorescence detection. J Agric Food Chem 1984, 32:794-797.
5. Alexandrov K., Rojas M., Satarug S. The critical DNA damage by benzo(a)pyrene in lung tissues of smokers and approaches to preventing its formation. Toxicol Lett 2010, 198:63-68.
6. Lee B.M., Shim G.A. Dietary exposure estimation of benzo[a]pyrene and cancer risk assessment. J Toxicol Environ Health 2007, A 68:1391-1394.
7. Rahman A., Barrowman J.A., Rahimtula A. The influence of bile on the bioavailability of polynuclear aromatic hydrocarbons from the rat intestine. Can J Physiol Pharmacol 1986, 64:1214-1218.
8. Barrowman J.A., Rahman A., Lindstrom M.B., Borgstrom B. Intestinal absorption and metabolism of hydrocarbons. Prog Lipid Res 1989, 28:189-203.
9. Laher J.M., Barrowman J.A. Intestinal absorption of carcinogenic hydrocarbons. Ann N Y Acad Sci 1988, 534:565-574.
10. Laher J.M., Barrowman J.A. Polycyclic hydrocarbon and polychlorinated biphenyl solubilization in aqueous solution of mixed micelles. Lipids 1983, 18:216-222.
11. Chan P.T., Fong W.P., Cheung Y.L., Huang Y., Ho W.K.K., Chen Z.Y. Jasmine green tea epicatechins are hypolipidemic in hamsters (Mesocricetus auratus) fed a high fat diet. J Nutr 1999, 129:1094-1101.
12. Yang M.H., Wang C.H., Chen H.L. Green, oolong and black tea extracts modulate lipid metabolism in hyperlipidemia rats fed high-sucrose diet. J Nutr Biochem 2001, 12:14-20.
13. Raederstorff D.G., Schlachter M.F., Elste V., Weber P. Effect of EGCG on lipid absorption and plasma lipid levels in rats. J Nutr Biochem 2003, 14:326-332.
14. Ikeda I., Imasato Y., Sasaki E., Nakayama M., Nagao H., Takeo T., et al. Tea catechins decrease micellar solubility and intestinal absorption of cholesterol in rats. Biochim Biophys Acta 1992, 1127:141-146.
15. Löest H.B., Noh S.K., Koo S.I. Green tea extract inhibits the lymphatic absorption of cholesterol and α-tocopherol in ovariectomized rats. J Nutr 2002, 132:1282-1288.
16. 2 and intestinal absorption of lipids in ovariectomized rats. J Nutr Biochem 2006, 17:492-498.
17. Wang S., Noh S.K., Koo S.I. Epigallocatechin gallate and caffeine differentially inhibit the intestinal absorption of cholesterol and fat in ovariectomized rats. J Nutr 2006, 136:2971-2976.
18. Koo S.I., Noh S.K. Green tea as inhibitor of the intestinal absorption of lipids: potential mechanism for its lipid-lowering effect. J Nutr Biochem 2007, 18:179-183.
19. Ikeda I., Kobayashi M., Hamada T., Tsuda K., Goto H., Iamizumi K., et al. Heat-epimerized tea catechins rich in gallocatechin gallate and catechin gallate are more effective to inhibit cholesterol absorption than tea catechins rich in epigallocatechin gallate and epicatechin gallate. J Agric Food Chem 2003, 51:7303-7307.
20. Morita K., Matsueda T., Lida T. Effect of green tea (matcha) on gastrointestinal tract absorption of polychlorinated biphenyls, polychlorinated dibenzofurans and polychlorinated dibenzo-p-dioxins in rats. Fukouka Igaku Zasshi 1997, 88:162-168.
21. Stavric B., Klassen R. Dietary effects on the uptake of benzo[a]pyrene. Food Chem Toxicol 1994, 32:727-734.
22. Reeves P.G., Nielsen F.H., Fahey G.C. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition Ad Hoc Writing Committee on the reformulation of the AIN-76A rodent diet. J Nutr 1993, 123:1939-1951.
23. Reeves P.G. AIN-93 purified diets for the study of trace element metabolism in rodents. Trace elements in laboratory rodents 1996, 3-37. CRC Press, Florida. R.R. Watson (Ed.).
24. Koo S.I., Noh S.K. Phosphatidylcholine inhibits and lysophosphatidylcholine enhances the lymphatic absorption of α-tocopherol in adult rats. J Nutr 2001, 131:717-722.
25. Noh S.K., Koo S.I. Milk sphingomyelin is more effective than egg sphingomyelin in inhibiting intestinal absorption of cholesterol and fat in rats. J Nutr 2004, 134:2611-2616.
26. Folch J., Lees M., Sloane-Stanley G.H. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 1957, 226:497-509.
27. Slover H.T., Lanza E. Quantitative analysis of food fatty acids by capillary gas chromatography. J Am Oil Chem Soc 1979, 56:933-943.
28. Zaspel B.J., Csallany A.S. Determination of alpha-tocopherol in tissues and plasma by high-performance liquid chromatography. Anal Biochem 1983, 130:146-150.
29. Shishikura Y., Khokhar S., Murray B.S. Effect of tea polyphenols on emulsification of olive oil in a small intestine model system. J Agric Food Chem 2006, 54:1906-1913.
30. Juhel C., Armand M., Pafumi Y., Rosier C., Vandermander J., Lairon D. Green tea extract (AR25) inhibits lipolysis of triglycerides in gastric and duodenal medium in vitro. J Nutr Biochem 2000, 11:45-51.
31. Buesen R., Mock M., Seidel A., Jacob J., Lampen A. Interaction between metabolism and transport of benzopyrene and its metabolites in enterocytes. Toxicol App Pharma 2002, 183:168-178.
32. Buesen R., Mock M., Nau H., Seidel A., Jacob J., Lampen A. Human intestinal Caco-2 cells display active transport of benzo[a]pyrene metabolites. Chem Biol Inter 2003, 142:201-221.
33. Fang C., Zhang Q.Y. The role of small-intestinal P450 enzymes in protection against systemic exposure of orally administered benzo[a]pyrene. J Pharmacol Exp Ther 2010, 334:156-163.
34. Ebert B., Seidel A., Lampen A. Identification of BCRP as transporter of benzo[a]pyrene conjugates metabolically formed in Caco-2 cells and its induction by Ah-receptor agonists. Carcinogenesis 2005, 26:1754-1763.
35. Ebert B., Seidel A., Lampen A. Induction of phase-1 metabolizing enzymes by oltipraz, flavones and indole-3-carbinol enhance the formation and transport of benzo[a]pyrene sulfate conjugates in intestinal Caco-2 cells. Toxicol Lett 2005, 158:140-151.
36. Ebert B., Seidel A., Lampen A. Phytochemicals induce breast cancer resistance protein in Caco-2 cells and enhance the transport of benzo[a]pyrene-3-sulfate. Toxicol Sci 2007, 96:227-236.
37. Bock K.W., Clausbruch U.C., Winne D. Absorption and metabolism of naphthalene and benzo(a)pyrene in the rat jejunum in situ. Med Biol 1979, 57:262-264.
38. Laher J.M., Rigler M.W., Vetter R.D., Barrowman J.A., Patton J.S. Similar bioavailability and lymphatic transport of benzo(a)pyrene when administered to rats in different amounts of dietary fat. J Lipid Res 1984, 25:1337-1342.
39. Maliakal P.P., Coville P.F., Wanwimolruk S. Tea consumption modulates hepatic drug metabolizing enzymes in Wistar rats. J Pharm Pharmacol 2001, 53:569-577.
40. Shu H.P., Bymun E.N. Systemic excretion of benzo(a)pyrene in the control and microsomally induced rat: the influence of plasma lipoproteins and albumin as carrier molecules. Cancer Res 1983, 43:485-490.
41. Sweeny D.J., Reinke L.A. Metabolism of benzo[a]pyrene in the perfused rat liver: factors affecting the release of phenolic metabolites into the bile and perfusate. Carcinogenesis 1987, 8:779-783.