Subacute toxicity assessment of water disinfection byproducts on zebrafish

Pathology and Oncology Research

Volumn 18, Issue 3, 2012, Pages 579-584

  Rácz, Gergely ^a   Csenki, Zsolt ^b   Kovács, Róbert ^b   Hegyi, Árpád ^b   Baska, Ferenc ^b   Sujbert, László ^a   Zsákovics, Ivett ^c   Kis, Renáta ^c   Gustafson, Ryan ^d   Urbányi, Béla ^b   Szende, Béla ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b SZENT ISTVÁN UNIVERSITY   (Hungary)

^c 3D HISTECH Kft ^*  (Hungary)

^d University of North Carolina at Chapel Hill   (United States)

Author keywords

2,4 Difluoroaniline; 4 Ethylbenzaldehyde; Water disinfection byproducts; Zebrafish

Indexed keywords

2,4 DIFLUOROANILINE; 4 ETHYLBENZALDEHYDE; DISINFECTANT AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; DYSTROPHY; HISTOPATHOLOGY; KIDNEY; LC 50; LETHARGY; LIVER; NONHUMAN; QUANTITATIVE ANALYSIS; SKIN; TOXICITY TESTING; ZEBRA FISH;

ANILINE COMPOUNDS; ANIMALS; DISINFECTION; DRINKING WATER; KIDNEY; LETHAL DOSE 50; LIVER; SKIN; WATER POLLUTANTS, CHEMICAL; ZEBRAFISH;

EID: 84863990538     PISSN: 12194956     EISSN: 15322807     Source Type: Journal    
DOI: 10.1007/s12253-011-9479-3     Document Type: Article

References (27)

1. Nieuwenhuijsen MJ, Toledano MB, Elliott P (2000) Uptake of chlorination disinfection by-products; a review and a discussion of its implications for exposure assessment in epidemiological studies. J Expo Anal Environ Epidemiol 10:586-599
2. Cognet L, Courtois Y, Mallevialle J (1986) Mutagenic activity of disinfection by-products. Environ Health Perspect 69:165-175
3. Woodruff NWet al (2001) Human cell mutagenicity of chlorinated and unchlorinated water and the disinfection byproduct 3-chloro-4- (dichloromethyl)-5-hydroxy-2(5H)-furanone (MX). Mutat Res 495:157-168
4. Morris RD et al (1992) Chlorination, chlorination by-products, and cancer: a meta-analysis. Am J Public Health 82:955-963
5. Bove GE Jr, Rogerson PA, Vena JE (2007) Case control study of the geographic variability of exposure to disinfectant byproducts and risk for rectal cancer. Int J Health Geogr 6:18
6. Villanueva CM et al (2007) Bladder cancer and exposure to water disinfection by-products through ingestion, bathing, showering, and swimming in pools. Am J Epidemiol 165:148-156
7. Sujbert L et al (2006) Genotoxic potential of by-products in drinking water in relation to water disinfection: survey of preozonated and post-chlorinated drinking water by Ames-test. Toxicology 219:106-112
8. Racz G et al (2004) Rapid communication: water disinfection byproducts enhanced apoptotic activity in human lymphocytes. J Toxicol Environ Health A 67:1315-1319
9. Krasner SW et al (2006) Occurrence of a new generation of disinfection byproducts. Environ Sci Technol 40:7175-7185
10. Berghmans S et al (2005) Making waves in cancer research: new models in the zebrafish. Biotechniques 39:227-237
11. Simon K, Lapis K (1984) Carcinogenesis studies on guppies. Natl Canc Inst Monogr 65:71-81
12. Amatruda JF et al (2002) Zebrafish as a cancer model system. Canc Cell 1:229-231
13. OECD, OECD 203 (1992) OECD Guidelines for testing of chemicals,
14. Effects on biotic systems. Method 203. Fish, Acute Toxicity Test. Adopted July 17, 1992
15. Mulrane L et al (2008) Automated image analysis in histopathology: a valuable tool in medical diagnostics. Expert Rev Mol Diagn 8:707-725
16. Krenacs T et al (2010) Digital microscopy for boosting database integration and analysis in TMA studies.MethMol Biol 664:163-175
17. Blaser RE, Chadwick L, McGinnis GC (2010) Behavioral measures of anxiety in zebrafish (Danio rerio). Behav Brain Res 208:56-62
18. Rook JJ (1974) Formation of haloforms during chlorination of natural waters. Wat Treat Exam 2:234-243
19. von Gunten U et al (2001) By-products formation during drinking water disinfection: a tool to assess disinfection efficiency? Water Res 35:2095-2099
20. Cantor KP (1982) Epidemiological evidence of carcinogenicity of chlorinated organics in drinking water. Environ Health Perspect 46:187-195
21. Plewa MJ et al (2002) Mammalian cell cytotoxicity and genotoxicity analysis of drinking water disinfection by-products. Environ Mol Mutagen 40:134-142
22. Lele Z, Krone PH (1996) The zebrafish as a model system in developmental, toxicological and transgenic research. Biotechnol Adv 14:57-72
23. Lammer E et al (2009) Development of a flow-through system for the fish embryo toxicity test (FET) with the zebrafish (Danio rerio). Toxicol In Vitro 23:1436-1442
24. Peterson SM, Freeman JL (2009) Cancer cytogenetics in the zebrafish. Zebrafish 6:355-360
25. Mione MC, Trede NS (2010) The zebrafish as a model for cancer. Dis Model Mech 3:517-523
26. Sullivan C, Kim CH (2008) Zebrafish as a model for infectious disease and immune function. Fish Shellfish Immunol 25:341-350
27. Khudoley VV (1984) Use of aquarium fish, Danio rerio and Poecilia reticulata, as test species for evaluation of nitrosamine carcinogenicity. Natl Canc Inst Monogr 65:65-70