Associations of ATP-binding cassette transporter A1 and G1 with insulin secretion in human insulinomas

Pancreas

Volumn 41, Issue 6, 2012, Pages 934-939

  Zhou, Huali ^a   Li, Chengjiang ^a   Li, Jun ^b   Yao, Hongtian ^b   Su, Rong ^b   Li, Wenpeng ^a   Xu, Mingzhi ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b BEIJING HOSPITAL   (China)

Author keywords

ATP binding cassette transporter A1; ATP binding cassette transporter G1; insulin secretion; insulinoma

Indexed keywords

ABC TRANSPORTER A1; ABC TRANSPORTER G1; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; ARTICLE; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULINOMA; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADULT; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL MARKERS; BLOOD GLUCOSE; CASE-CONTROL STUDIES; CHINA; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOHISTOCHEMISTRY; INSULIN; INSULINOMA; LIPIDS; MALE; MIDDLE AGED; PANCREATIC NEOPLASMS; TIME FACTORS;

EID: 84863989189     PISSN: 08853177     EISSN: 15364828     Source Type: Journal    
DOI: 10.1097/MPA.0b013e318243a5e3     Document Type: Article

References (21)

1. Guettier JM, Gorden P. Insulin secretion and insulin-producing tumors. Expert Rev Endocrinol Metab. 2010;5:217Y227.
2. Koehn J, Fountoulakis M, Krapfenbauer K. Multiple drug resistance associated with function of ABC-transporters in diabetes mellitus: molecular mechanism and clinical relevance. Infect Disord Drug Targets. 2008;8:109Y118.
3. Sturek JM, Castle JD, Trace AP, et al. An intracellular role for ABCG1-mediated cholesterol transport in the regulated secretory pathway of mouse pancreatic beta cells. J Clin Invest. 2010;120: 2575Y2589.
4. Sempoux C, Guiot Y, Dahan K, et al. The focal form of persistent hyperinsulinemic hypoglycemia of infancy: morphological and molecular studies show structural and functional differences with insulinoma. Diabetes. 2003;52:784Y794.
5. Brunham LR, Kruit JK, Verchere CB, et al. Cholesterol in islet dysfunction and type 2 diabetes. J Clin Invest. 2008;118: 403Y408.
6. Gerin I, Dolinsky VW, Shackman JG, et al. LXRbeta is required for adipocyte growth, glucose homeostasis, and beta cell function. J Biol Chem. 2005;280:23024Y23031.
7. Zitzer H,WenteW, Brenner MB, et al. Sterol regulatory element-binding protein 1 mediates liver X receptor-betaYinduced increases in insulin secretion and insulin messenger ribonucleic acid levels. Endocrinology. 2006;147:3898Y3905.
8. Brunham LR, Kruit JK, Pape TD, et al. Beta-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment. Nat Med. 2007;13:340Y347.
9. Kruit JK, Kremer PH, Dai L, et al. Cholesterol efflux via ATP-binding cassette transporter A1 (ABCA1) and cholesterol uptake via the LDL receptor influences cholesterol-induced impairment of beta cell function in mice. Diabetologia. 2010;53:1110Y1119.
10. Vergeer M, Brunham LR, Koetsveld J, et al. Carriers of loss-of-function mutations in ABCA1 display pancreatic beta-cell dysfunction. Diabetes Care. 2010;33:869Y874.
11. Koseki M, Matsuyama A, Nakatani K, et al. Impaired insulin secretion in four Tangier disease patients with ABCA1 mutations. J Atheroscler Thromb. 2009;16:292Y296.
12. Engel T, Kannenberg F, Fobker M, et al. Expression of ATP binding cassette-transporter ABCG1 prevents cell death by transporting cytotoxic 7beta-hydroxycholesterol. FEBS Lett. 2007;581:1673Y1680.
13. Terasaka N, Wang N, Yvan-Charvet L, et al. High-density lipoprotein protects macrophages from oxidized low-density lipoprotein-induced apoptosis by promoting efflux of 7-ketocholesterol via ABCG1. Proc Natl Acad Sci U S A. 2007;104:15093Y15098.
14. Fryirs M, Barter PJ, Rye KA. Cholesterol metabolism and pancreatic beta-cell function. Curr Opin Lipidol. 2009;20:159Y164.
15. Buechler C, Bared SM, Aslanidis C, et al. Molecular and functional interaction of the ATP-binding cassette transporter A1 with Fas-associated death domain protein. J Biol Chem. 2002;277:41307Y41310.
16. Gussinyer M, Clemente M, Cebrián R, et al. Glucose intolerance and diabetes are observed in the long-term follow-up of nonpancreatectomized patients with persistent hyperinsulinemic hypoglycemia of infancy due to mutations in the ABCC8 gene. Diabetes Care. 2008;31:1257Y1259.
17. Abdulhadi-Atwan M, Bushman J, Tornovsky-Babaey S, et al. Novel de novo mutation in sulfonylurea receptor 1 presenting as hyperinsulinism in infancy followed by overt diabetes in early adolescence. Diabetes. 2008;57:1935Y1940.
18. Grimberg A, Ferry RJ Jr, Kelly A, et al. Dysregulation of insulin secretion in children with congenital hyperinsulinism due to sulfonylurea receptor mutations. Diabetes. 2001;50:322Y328.
19. Aquilante CL. Sulfonylurea pharmacogenomics in Type 2 diabetes: the influence of drug target and diabetes risk polymorphisms. Expert Rev Cardiovasc Ther. 2010;8:359Y372.
20. Xu H, Murray M, McLachlan AJ. Influence of genetic polymorphisms on the pharmacokinetics and pharmaco-dynamics of sulfonylurea drugs. Curr Drug Metab. 2009;10:643Y658.
21. Darendeliler F, Fournet JC, Baz F, et al. ABCC8 (SUR1) and KCNJ11 (KIR6.2) mutations in persistent hyperinsulinemic hypoglycemia of infancy and evaluation of different therapeutic measures. J Pediatr Endocrinol Metab. 2002;15:993Y1000. Pancreas & Volume 41, Number 6, August 2012 ABCA1 and ABCG1 in Insulinomas