Renal angina: An emerging paradigm to identify children at risk for acute kidney injury

Pediatric Nephrology

Volumn 27, Issue 7, 2012, Pages 1067-1078

  Basu, Rajit K ^a   Chawla, Lakhmir S ^b   Wheeler, Derek S ^a   Goldstein, Stuart L ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Acute kidney injury; Renal angina; Scoring systems

Indexed keywords

AMINOPEPTIDASE; CREATININE; CYSTATIN C; GAMMA GLUTAMYLTRANSFERASE; GELATINASE B; GLUTATHIONE TRANSFERASE; INTERLEUKIN 18; KIDNEY INJURY MOLECULE 1; LACTATE DEHYDROGENASE; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN;

ACUTE KIDNEY FAILURE; APACHE; ARTIFICIAL VENTILATION; CREATININE BLOOD LEVEL; DISEASE COURSE; DISEASE SEVERITY; FOLLOW UP; GLOMERULUS FILTRATION RATE; HOSPITAL COST; HUMAN; INTENSIVE CARE; KIDNEY DISEASE; KIDNEY PERFUSION; LACTATE DEHYDROGENASE BLOOD LEVEL; LENGTH OF STAY; LOGISTIC ORGAN DYSFUNCTION SCORE; MORTALITY; MULTIPLE ORGAN DYSFUNCTION SCORE; PREDICTIVE VALUE; PRIORITY JOURNAL; RENAL ANGINA; RENAL REPLACEMENT THERAPY; REVIEW; RISK FACTOR; SCORING SYSTEM; SEQUENTIAL ORGAN FAILURE ASSESSMENT; SURVIVAL PREDICTION; UREA BLOOD LEVEL; URINE VOLUME;

ACUTE KIDNEY INJURY; BIOLOGICAL MARKERS; CHILD; EARLY DIAGNOSIS; HUMANS; RISK FACTORS; SEVERITY OF ILLNESS INDEX;

EID: 84863988283     PISSN: 0931041X     EISSN: 1432198X     Source Type: Journal    
DOI: 10.1007/s00467-011-2024-5     Document Type: Review

References (73)

1. Uchino S, Kellum JA, Bellomo R, Doig GS, Morimatsu H, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, Gibney N, Tolwani A, Ronco C (2005) Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA 294:813-818 (Pubitemid 41175724)
2. Hoste EA, Schurgers M (2008) Epidemiology of acute kidney injury: how big is the problem? Crit Care Med 36:S146-S151 (Pubitemid 351483044)
3. Basu RK, Devarajan P, Wong H, Wheeler DS (2011) An update and review of acute kidney injury in pediatrics. Pediatr Crit Care Med 12:339-347
4. Hui-Stickle S, Brewer ED, Goldstein SL (2005) Pediatric ARF epidemiology at a tertiary care center from 1999 to 2001. Am J Kidney Dis 45:96-101 (Pubitemid 40038049)
5. Akcan-Arikan A, Zappitelli M, Loftis LL, Washburn KK, Jefferson LS, Goldstein SL (2007) Modified RIFLE criteria in critically ill children with acute kidney injury. Kidney Int 71:1028-1035 (Pubitemid 46741996)
6. Symons JM, Chua AN, Somers MJ, Baum MA, Bunchman TE, Benfield MR, Brophy PD, Blowey D, Fortenberry JD, Chand D, Flores FX, Hackbarth R, Alexander SR, Mahan J, McBryde KD, Goldstein SL (2007) Demographic characteristics of pediatric continuous renal replacement therapy: a report of the prospective pediatric continuous renal replacement therapy registry. Clin J Am Soc Nephrol 2:732-738
7. Chawla LS, Amdur RL, Amodeo S, Kimmel PL, Palant CE (2011) The severity of acute kidney injury predicts progression to chronic kidney disease. Kidney Int 79:1361-1369
8. Liu KD (2009) Impact of acute kidney injury on lung injury. Am J Physiol Lung Cell Mol Physiol 296:L1-L2
9. Doi K, Ishizu T, Fujita T, Noiri E (2011) Lung injury following acute kidney injury: kidney-lung crosstalk. Clin Exp Nephrol 15:464-470
10. Hoste EA, Kellum JA (2007) Incidence, classification, and outcomes of acute kidney injury. Contrib Nephrol 156:32-38
11. Zappitelli M, Bernier PL, Saczkowski RS, Tchervenkov CI, Gottesman R, Dancea A, Hyder A, Alkandari O (2009) A small post-operative rise in serum creatinine predicts acute kidney injury in children undergoing cardiac surgery. Kidney Int 76:885-892
12. Goldstein SL, Chawla LS (2010) Renal angina. Clin J Am Soc Nephrol 5:943-949
13. Hoste EA, Kellum JA (2006) Acute kidney dysfunction and the critically ill. Minerva Anestesiol 72:133-143
14. Hoste EA, De Waele JJ (2008) Acute kidney injury in the intensive care unit: it's the gene, stupid! Crit Care Med 36:3266-3267
15. Hoste EA, Clermont G, Kersten A, Venkataraman R, Angus DC, De Bacquer D, Kellum JA (2006) RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: a cohort analysis. Crit Care 10:R73
16. Schneider J, Khemani R, Grushkin C, Bart R (2010) Serum creatinine as stratified in the RIFLE score for acute kidney injury is associated with mortality and length of stay for children in the pediatric intensive care unit. Crit Care Med 38:933-939
17. Zappitelli M (2008) Epidemiology and diagnosis of acute kidney injury. Semin Nephrol 28:436-446
18. Brophy PD (2008) Renal supportive therapy for pediatric acute kidney injury in the setting of multiorgan dysfunction syndrome/sepsis. Semin Nephrol 28:457-469
19. Askenazi DJ, Ambalavanan N, Hamilton K, Cutter G, Laney D, Kaslow R, Georgeson K, Barnhart DC, Dimmitt RA (2010) Acute kidney injury and renal replacement therapy independently predict mortality in neonatal and pediatric noncardiac patients on extracorporeal membrane oxygenation. Pediatr Crit Care Med 12:e1-e6
20. Skippen PW, Krahn GE (2005) Acute renal failure in children undergoing cardiopulmonary bypass. Crit Care Resusc 7:286-291
21. Picca S, Principato F, Mazzera E, Corona R, Ferrigno L, Marcelletti C, Rizzoni G (1995) Risks of acute renal failure after cardiopulmonary bypass surgery in children: a retrospective 10-year case-control study. Nephrol Dial Transplant 10:630-636
22. Blinder JJ, Goldstein SL, Lei VV, Baycroft A, Fraser CD Jr, Nelson DP, Jefferies JL (2011) Congenital heart surgery in infants: Effects of acute kidney injury on outcomes. J Thorac Cardiovasc Surg. doi:10.1016/j.jtcvs.2011.06.021
23. Ueki M, Asaga T, Chujo K, Ono J, Iwanaga Y, Taie S (2008) D-allose protects against endotoxemic acute renal injury. J Biosci Bioeng 105:481-485 (Pubitemid 351815028)
24. Himmelfarb J, Joannidis M, Molitoris B, Schietz M, Okusa MD, Warnock D, Laghi F, Goldstein SL, Prielipp R, Parikh CR, Pannu N, Lobo SM, Shah S, D'Intini V, Kellum JA (2008) Evaluation and initial management of acute kidney injury. Clin J Am Soc Nephrol 3:962-967
25. Andreoli SP (2008) Management of acute kidney injury in children: a guide for pediatricians. Paediatr Drugs 10:379-390
26. Bunchman TE (2008) Treatment of acute kidney injury in children: from conservative management to renal replacement therapy. Nat Clin Pract Nephrol 4:510-514
27. Kellum JA, Decker JM (2001) Use of dopamine in acute renal failure: a meta-analysis. Crit Care Med 29:1526-1531 (Pubitemid 32762331)
28. Moffett BS, Mott AR, Nelson DP, Goldstein SL, Jefferies JL (2008) Renal effects of fenoldopam in critically ill pediatric patients: A retrospective review. Pediatr Crit Care Med 9:403-406
29. Basu R, Wheeler D (2011) Approaches to the Management of Acute Kidney Injury in Children. Recent Patents Biomarkers 1:49-59
30. Cole L, Bellomo R, Hart G, Journois D, Davenport P, Tipping P, Ronco C (2002) A phase II randomized, controlled trial of continuous hemofiltration in sepsis. Crit Care Med 30:100-106 (Pubitemid 34112184)
31. Murugan R, Karajala-Subramanyam V, Lee M, Yende S, Kong L, Carter M, Angus DC, Kellum JA (2010) Acute kidney injury in non-severe pneumonia is associated with an increased immune response and lower survival. Kidney Int 77:527-535
32. Goldstein SL, Somers MJ, Baum MA, Symons JM, Brophy PD, Blowey D, Bunchman TE, Baker C, Mottes T, McAfee N, Barnett J, Morrison G, Rogers K, Fortenberry JD (2005) Pediatric patients with multi-organ dysfunction syndrome receiving continuous renal replacement therapy. Kidney Int 67:653-658 (Pubitemid 40139857)
33. Sutherland SM, Zappitelli M, Alexander SR, Chua AN, Brophy PD, Bunchman TE, Hackbarth R, Somers MJ, Baum M, Symons JM, Flores FX, Benfield M, Askenazi D, Chand D, Fortenberry JD, Mahan JD, McBryde K, Blowey D, Goldstein SL (2010) Fluid overload and mortality in children receiving continuous renal replacement therapy: the prospective pediatric continuous renal replacement therapy registry. Am J Kidney Dis 55:316-325
34. Kellum JA, Angus DC (2002) Patients are dying of acute renal failure. Crit Care Med 30:2156-2157
35. Murugan R, Kellum JA (2011) Acute kidney injury: what's the prognosis? Nat Rev Nephrol 7:209-217
36. Zappitelli M, Goldstein SL, Symons JM, Somers MJ, Baum MA, Brophy PD, Blowey D, Fortenberry JD, Chua AN, Flores FX, Benfield MR, Alexander SR, Askenazi D, Hackbarth R, Bunchman TE (2008) Protein and calorie prescription for children and young adults receiving continuous renal replacement therapy: a report from the Prospective Pediatric Continuous Renal Replacement Therapy Registry Group. Crit Care Med 36:3239-3245
37. Goldstein SL (2007) Kidney function assessment in the critically ill child: is it time to leave creatinine behind? Crit Care 11:141
38. Parikh CR, Lu JC, Coca SG, Devarajan P (2010) Tubular proteinuria in acute kidney injury: a critical evaluation of current status and future promise. Ann Clin Biochem 47:301-312
39. Coca SG, Yalavarthy R, Concato J, Parikh CR (2008) Biomarkers for the diagnosis and risk stratification of acute kidney injury: a systematic review. Kidney Int 73:1008-1016 (Pubitemid 351543898)
40. Siew ED, Ware LB, Ikizler TA (2011) Biological markers of acute kidney injury. J Am Soc Nephrol 22:810-820
41. Vincent JL, Moreno R (2010) Clinical review: scoring systems in the critically ill. Crit Care 14:207
42. Vincent JL, Bruzzi de Carvalho F (2010) Severity of illness. Semin Respir Crit Care Med 31:31-38
43. Fiaccadori E, Maggiore U, Lombardi M, Leonardi S, Rotelli C, Borghetti A (2000) Predicting patient outcome from acute renal failure comparing three general severity of illness scoring systems. Kidney Int 58:283-292 (Pubitemid 30429873)
44. Knaus WA, Draper EA, Wagner DP, Zimmerman JE (1985) APACHE II: a severity of disease classification system. Crit Care Med 13:818-829 (Pubitemid 15250137)
45. Le Gall JR, Lemeshow S, Saulnier F (1993) A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study. JAMA 270:2957-2963 (Pubitemid 24000804)
46. Lemeshow S, Teres D, Klar J, Avrunin JS, Gehlbach SH, Rapoport J (1993) Mortality Probability Models (MPM II) based on an international cohort of intensive care unit patients. JAMA 270:2478-2486 (Pubitemid 23342299)
47. Lemeshow S, Teres D, Avrunin JS, Gage RW (1988) Refining intensive care unit outcome prediction by using changing probabilities of mortality. Crit Care Med 16:470-477
48. Pollack MM, Ruttimann UE, Getson PR (1988) Pediatric risk of mortality (PRISM) score. Crit Care Med 16:1110-1116 (Pubitemid 18267293)
49. Pollack MM, Patel KM, Ruttimann UE (1996) PRISM III: an updated Pediatric Risk of Mortality score. Crit Care Med 24:743-752 (Pubitemid 26155716)
50. Pollack MM, Patel KM, Ruttimann U, Cuerdon T (1996) Frequency of variable measurement in 16 pediatric intensive care units: influence on accuracy and potential for bias in severity of illness assessment. Crit Care Med 24:74-77
51. Moreno R, Vincent JL, Matos R, Mendonca A, Cantraine F, Thijs L, Takala J, Sprung C, Antonelli M, Bruining H, Willatts S (1999) The use of maximum SOFA score to quantify organ dysfunction/failure in intensive care. Results of a prospective, multicentre study. Working Group on Sepsis related Problems of the ESICM. Intensive Care Med 25:686-696 (Pubitemid 29376122)
52. Leteurtre S, Martinot A, Duhamel A, Gauvin F, Grandbastien B, Nam TV, Proulx F, Lacroix J, Leclerc F (1999) Development of a pediatric multiple organ dysfunction score: use of two strategies. Med Decis Making 19:399-410 (Pubitemid 29474766)
53. Leteurtre S, Martinot A, Duhamel A, Proulx F, Grandbastien B, Cotting J, Gottesman R, Joffe A, Pfenninger J, Hubert P, Lacroix J, Leclerc F (2003) Validation of the paediatric logistic organ dysfunction (PELOD) score: prospective, observational, multicentre study. Lancet 362:192-197 (Pubitemid 36859934)
54. Uchino S, Bellomo R, Morimatsu H, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, Gibney N, Tolwani A, Doig GS, Oudemans van Straaten H, Ronco C, Kellum JA (2005) External validation of severity scoring systems for acute renal failure using a multinational database. Crit Care Med 33:1961-1967 (Pubitemid 41306516)
55. Mehta RL, Chertow GM (2003) Acute renal failure definitions and classification: time for change? J Am Soc Nephrol 14:2178-2187 (Pubitemid 36909928)
56. Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P (2004) Acute renal failure-definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care 8:R204-R212
57. Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, Levin A (2007) Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care 11:R31
58. Hoste EA, Kellum JA (2006) RIFLE criteria provide robust assessment of kidney dysfunction and correlate with hospital mortality. Crit Care Med 34:2016-2017 (Pubitemid 43982486)
59. Chang CH, Lin CY, Tian YC, Jenq CC, Chang MY, Chen YC, Fang JT, Yang CW (2010) Acute kidney injury classification: comparison of AKIN and RIFLE criteria. Shock 33:247-252
60. Plotz FB, Bouma AB, van Wijk JA, Kneyber MC, Bokenkamp A (2008) Pediatric acute kidney injury in the ICU: an independent evaluation of pRIFLE criteria. Intensive Care Med 34:1713-1717
61. Duzova A, Bakkaloglu A, Kalyoncu M, Poyrazoglu H, Delibas A, Ozkaya O, Peru H, Alpay H, Soylemezoglu O, Gur-Guven A, Bak M, Bircan Z, Cengiz N, Akil I, Ozcakar B, Uncu N, Karabay-Bayazit A, Sonmez F (2010) Etiology and outcome of acute kidney injury in children. Pediatr Nephrol 25:1453-1461
62. Palmieri T, Lavrentieva A, Greenhalgh D (2009) An assessment of acute kidney injury with modified RIFLE criteria in pediatric patients with severe burns. Intensive Care Med 35:2125-2129
63. Cartin-Ceba R, Haugen EN, Iscimen R, Trillo-Alvarez C, Juncos L, Gajic O (2009) Evaluation of "Loss" and "End stage renal disease" after acute kidney injury defined by the Risk, Injury, Failure, Loss and ESRD classification in critically ill patients. Intensive Care Med 35:2087-2095
64. Parikh CR, Mishra J, Thiessen-Philbrook H, Dursun B, Ma Q, Kelly C, Dent C, Devarajan P, Edelstein CL (2006) Urinary IL-18 is an early predictive biomarker of acute kidney injury after cardiac surgery. Kidney Int 70:199-203 (Pubitemid 44000139)
65. Simmons EM, Himmelfarb J, Sezer MT, Chertow GM, Mehta RL, Paganini EP, Soroko S, Freedman S, Becker K, Spratt D, Shyr Y, Ikizler TA (2004) Plasma cytokine levels predict mortality in patients with acute renal failure. Kidney Int 65:1357-1365 (Pubitemid 38406974)
66. Ahlstrom A, Tallgren M, Peltonen S, Pettila V (2004) Evolution and predictive power of serum cystatin C in acute renal failure. Clin Nephrol 62:344-350 (Pubitemid 39480840)
67. Zappitelli M, Washburn KK, Arikan AA, Loftis L, Ma Q, Devarajan P, Parikh CR, Goldstein SL (2007) Urine neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in critically ill children: a prospective cohort study. Crit Care 11:R84
68. Mishra J, Dent C, Tarabishi R, Mitsnefes MM, Ma Q, Kelly C, Ruff SM, Zahedi K, Shao M, Bean J, Mori K, Barasch J, Devarajan P (2005) Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery. Lancet 365:1231-1238 (Pubitemid 40469655)
69. Al-Ismaili Z, Palijan A, Zappitelli M (2011) Biomarkers of acute kidney injury in children: discovery, evaluation, and clinical application. Pediatr Nephrol 26:29-40
70. Bailey D, Phan V, Litalien C, Ducruet T, Merouani A, Lacroix J, Gauvin F (2007) Risk factors of acute renal failure in critically ill children: A prospective descriptive epidemiological study. Pediatr Crit Care Med 8:29-35 (Pubitemid 46168354)
71. Michael M, Kuehnle I, Goldstein SL (2004) Fluid overload and acute renal failure in pediatric stem cell transplant patients. Pediatr Nephrol 19:91-95 (Pubitemid 38088257)
72. Kist-van Holthe JE, Goedvolk CA, Brand R, van Weel MH, Bredius RG, van Oostayen JA, Vossen JM, van der Heijden BJ (2002) Prospective study of renal insufficiency after bone marrow transplantation. Pediatr Nephrol 17:1032-1037 (Pubitemid 36097647)
73. Goldstein SL (2011) Advances in pediatric renal replacement therapy for acute kidney injury. Semin Dial 24:187-191