High APOE epsilon 4 allele frequencies associated with Alzheimer disease in a Tunisian population

Neurological Sciences

Volumn 33, Issue 1, 2012, Pages 33-37

  Rassas, Afef Achouri ^a,c   Khiari, Hela Mrabet ^a,b   Fredj, Sondes Hadj ^c   Sahnoun, Safa ^c   Batti, Hend ^a   Zakraoui, Nouria Oudiaa ^a   Cherif, Aroua ^a   Anane, Nadia ^a   Ben Ali, Nadia ^a   Messaoud, Taieb ^c   Mrabet, Amel ^a,b  

^a CHARLES NICOLLE HOSPITAL   (Tunisia)

^b UNIVERSITY OF TUNIS EL MANAR   (Tunisia)

^c CHILDREN S HOSPITAL   (Tunisia)

Author keywords

Alzheimer disease; Apolipoprotein E; Molecular diagnosis; Risk factor

Indexed keywords

APOLIPOPROTEIN E4; GENOMIC DNA;

AGED; ALLELE; ALZHEIMER DISEASE; APOE EPSILON 4; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; MINI MENTAL STATE EXAMINATION; NEUROIMAGING; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; TUNISIA;

AGED; AGED, 80 AND OVER; ALLELES; ALZHEIMER DISEASE; APOLIPOPROTEIN E4; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENOTYPE; HUMANS; MALE; MIDDLE AGED; TUNISIA;

EID: 84863987432     PISSN: 15901874     EISSN: 15903478     Source Type: Journal    
DOI: 10.1007/s10072-011-0663-8     Document Type: Article

References (46)

1. National Institute on Aging/Alzheimer's Association Working Group (1996) Apolipoprotein E genotyping in Alzheimer's disease. Lancet 347:1091-1095
2. Breitner JC, Wyse BW, Anthony JC (1999) ApoE-epsilon4 count predicts age when prevalence of AD increases, then declines: the Cache County study. Neurology 53:321-331 (Pubitemid 29344354)
3. Terwilliger JD, Ott J (1994) Linkage disequilibrium between alleles at marker loci. In: Handbook of human genetic linkage, The John Hopkins University Press, Baltimore, pp 188-198
4. Zhong N, Weisgraber KH (2009) Understanding the association of apolipoprotein E4 with Alzheimer disease: clues from its structure. J Biol Chem 284:6027-6031
5. Farrer LA, Friedland RP, Bowirrat A, Waraska K, Korczyn A, Baldwin C (2003) Genetic and environmental epidemiology of Alzheimer's disease in Arabs residing in Israel. J Mol Neurosci 20:207-212 (Pubitemid 38146973)
6. Chien-Hsiun C, Toshiki M, Elston R, Kariuki M, Hall K, Unverzagt F et al (2010) A comparative study to screen dementia and APOE genotypes in an ageing East African population. Neurobiol Aging 31:732-740
7. Kalaria RN, Ogeng'o JA, Patel NB, Sayi JG, Kitinya JN, Chande HM et al (1997) Evaluation of risk factors for Alzheimer's disease in elderly east Africans. Brain Res Bull 44:573-577 (Pubitemid 27494674)
8. Sayi JG, Patel NB, Premkumar DR, Adem A, Winblad B, Matuja WB et al (1997) Apolipoprotein E polymorphism in elderly east Africans. East Afr Med J 74:668-670
9. Bellaj T, Ben Jemaa S, Attia Romdhane N, Dhiffallah M, Bouaziz M, Mrabet A (2008) Mini mental state examination Arabic version (A-MMSE): reliability, validity and normative data. La Tunisie Medicale 86:768-776
10. Ben Jemaa S, Bellaj T, Attia Romdhane N, Oudiaa Zakraoui N, Cherif A et al (2008) Arabic version of the Alzheimer's disease assessment scale cognitive subscale (A-ADAS COG). La Tunisie Medicale 86:777-785
11. Ben Jemaa S, Bellaj T, Attia Romdhane N, Cherif A, Oudiaa Zakraoui N, Bouaziz M et al (2008) Frontal assessment battery: reliability, validity and standardization of an Arabic form. La Tunisie Medicale 86:793-800
12. Bellaj T, Ben Jemaa S, Anane N, Attia Romdhane N, Ben Youssef K, Kahouaji H et al (2008) Geriatric depression scale Arabic version: reliability, validity and normative data. La Tunisie Medicale 86:801-808
13. Ben Hamouda I, Attia Romdhane N, Ben Youssef K, Mhenni C, Mrabet A (2008) Interrater reliability of the clinical dementia rating scale in Tunisia. La Tunisie Medicale 86:764-767
14. Attia Romdhane N, Ben Hamouda I, Ben Youssef K, Mhenni C, Ouenniche S, Mrabet A (2008) Reliability and validity of instrumental activities in daily living scale in Tunisia. La Tunisie Medicale 86:764-767
15. American Psychiatric Association (APA) (1993) Diagnostic and statistical manual of mental disorders. DSM-IV, 4th edn. American Psychiatric Association, Washington, DC
16. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinial diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease. Neurology 34:939-944 (Pubitemid 14076461)
17. Bienvenu T, Meunier C, Bousquet S, Chiron S, Richard L, Gauther-Dejean A, Rouselle J-F, Feldmann D (1999) Les techniques d'extraction de l'ADN à partir d'un échantillon sanguin. Ann Biol Clin 57:77-84 (Pubitemid 129755165)
18. Miller SA, Dykes D, Polesky HF (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16:12-15
19. Hixson JE, Vernier DT (1990) Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res 31:545-548 (Pubitemid 20107994)
20. Hajjem S, Achour N (2001) Espérance de vie sans incapacité de la population tunisienne âgée. Institut National de la Santé Publique, Tunis, pp 17-25
21. Hajem S, Mrabet A (2008) Epidémiologie des démences en Tunisie. La Tunisie Medicale 86:744-745
22. Malle E, Pfeiffer KP, Dugi K, Pfeiffer C, Glaum M, Oezcueruemez M et al (1996) Polymorphisms of apolipoprotein A-IV and E in a Turkish population living in Germany. Hum Genet 98:285-290 (Pubitemid 26258375)
23. Chartier-Harlin MC, Parfitt M, Legrain S, Pérez-Tur J, Brousseau T, Evans A et al (1994) Apolipoprotein E, epsilon 4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: analysis of the 19q13.2 chromosomal region. Hum Mol Genet 4:569-574
24. Betard C, Robitaille Y, Gee M, Tiberghien D, Larrivée D, Roy P et al (1994) Apo E allele frequencies in Alzheimer's disease, Lewy body dementia, Alzheimer's disease with cerebrovascular disease and vascular dementia. Neuroreport 15:1893-1896 (Pubitemid 24305414)
25. Raygani A, RahimiZ KharaziH, Tavilani H, Pourmotabbed T (2006) Association between apolipoprotein E polymorphism and serum lipid and apolipoprotein levels with Alzheimer's disease. Neurosci Lett 408:68-72 (Pubitemid 44466204)
26. Cariobu MA, Kokkofitou A, Manoli P, Christou S, Karagrigoriou A, Middleton L (1995) Under expression of the apolipoprotein E2 and E4 alleles in the Greek Cypriot population of Cyprus. Genet Epidemiol 12:489-497
27. Norihiro T, Akinori M, Tamao T, Hiroyuki A, Takashi A, The Japanese Genetic Study Consortium for Alzheimer disease et al (2009) Genetic association study on in and around the APOE in late-onset Alzheimer disease in Japanese. Genomics 93:441-448
28. Valveny N, Esteban E, Kandi M, Moral P (1997) APOE Polymorphism in Spanish and Moroccan populations. Clin Genet 51:354-356 (Pubitemid 27248271)
29. Bosco P, Gueant-Rodriguez R, Anello G, Spada R, Romano A, Caraci F et al (2005) Allele e4 of APOE is a stronger predictor of Alzheimer risk in Sicily than in continental South Italy. Neurosci Lett 388:168-172 (Pubitemid 41208214)
30. Piscopo P, Manfredi A, Malvezzi-Campeggi L, Crestini A, Spadoni O, Cherchi R et al (2006) Genetic study of Sardinian patients with Alzheimer's disease. Neurosci Lett 398:124-128
31. Poli M, Benerini Gatta L, Lovati C, Mariani C, Galimberti D, Scarpini E et al (2008) Interaction between the APOE 4 allele and the APH-1b c+651T>G SNP in Alzheimer's disease. Neurobiol Aging 29:1494-1501
32. Gureje O, Ogunniyi A, Baiyewu O, Price B, Unverzagt FW et al (2006) APOE epsilon4 is not associated with Alzheimer's disease in elderly Nigerians. Ann Neurol 59:182-185 (Pubitemid 43042886)
33. Heckmann JM, Low WC, De Villiers C, Rutherfoord S, Vorster A, Rao H et al (2004) Novel presenilin 1 mutation with profound neurofibrillary pathology in an indigenous Southern African family with early-onset Alzheimer's disease. Brain 127:133-142 (Pubitemid 38055352)
34. Osuntokun BO, Sahota A, Ogunniyi AO, Gureje O, Baiyewu O, Adeyinka A et al (1995) Lack of an association between apolipoprotein E epsilon 4 and Alzheimer's disease in elderly Nigerians. Ann Neurol 38:463-465
35. Maestre G, Ottman R, Stern Y, Mayeux R (1995) Apolipoprotein E and Alzheimer's disease: ethnic variation in genotype risks. Ann Neurol 37:254-259
36. Hendrie HC, Hall KS, Hui S (1995) Apolipoprotein E genotypes and Alzheimer's disease in a community study of elderly African Americans. Ann Neurol 37:118-121
37. Seripa D, Panza F, Franceschi M, D' Onofrio G, Solfrizzi V, Dallapiccola B, Pilotto A (2009) Non-apolipoprotein E and apolipoprotein E genetics of sporadic Alzheimer's disease. Ageing Res Rev 8:214-236
38. Lambert JC, Pasquier F, Cottel D, Frigard B, Amouyel P, Chritier-harlin MC (1998) A new polymorphism in the ApoE promoter associated with risk of developing Alzheimer disease. Hum Med Genet 3:533-540 (Pubitemid 28120646)
39. Kim KW, Jhoo JH, Lee KU, Lee DY, Lee JH, Youn JY, Lee BJ, Han SJ, Woo JI (1999) Association between apolipoprotein E polymorphism and Alzheimer's disease in Koreans. Neurosci Lett 277:145-148
40. Mak YT, Chiu H, Woo J, Kay R, Chan YS, Hui E, Sze KH, Lun C, Kwok T, Pang CP (1996) Apolipoprotein E genotype and Alzheimer's disease in Hong Kong elderly Chinese. Neurology 46:146-149 (Pubitemid 26156120)
41. Slooter AJ, Cruts M, Kalmijn S, Hofman A, Breteler MM, Van Broeckhoven C, van Duijn CM (1998) Risk estimates of dementia by apolipoprotein E genotypes from a population-based incidence study: the Rotterdam Study. Arch Neurol 55:964-968 (Pubitemid 28335115)
42. Yadong H (2010) A-β-independent roles of apolipoprotein E4 in the pathogenesis of Alzheimer's disease. Trends Mol Med 16:287-294
43. Richard F, Amouyel P (2001) Genetic susceptibility factors for Alzheimer's disease. Eur J Pharmacol 412:1-12 (Pubitemid 32149763)
44. Thomas P, Fenech M (2007) A review of genome mutation and Alzheimer's disease. Mutagenesis 22:15-33 (Pubitemid 46058638)
45. Lopez OL, Pouse S, Kamboh M, Androer R, Gallego ML, Becker JT et al (1998) Apolipoprotein E polymorphism in Alzheimer' disease: a comparative study of two search populations from Spain and the USA. Eur Neuol 39:229-233 (Pubitemid 28230403)
46. Carrillo Maria C, Blackwell Andrew, Hampel Harald, Lindborg Johan, Sperling Reisa, Schenk Dale et al (2009) Early risk assessment for Alzheimer's disease. Alzheimer's Dementia 5:182-196