Development of novel antibacterial agents against methicillin-resistant Staphylococcus aureus

Bioorganic and Medicinal Chemistry

Volumn 20, Issue 15, 2012, Pages 4653-4660

  Chiu, Hao Chieh ^a   Lee, Su Lin ^b   Kapuriya, Naval ^b   Wang, Dasheng ^b   Chen, Yi Ru ^a   Yu, Sung Liang ^a   Kulp, Samuel K ^b   Teng, Lee Jene ^a   Chen, Ching Shih ^b,c  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b OHIO STATE UNIVERSITY   (United States)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Anti infection agents; Anti MRSA agents; Staphylococcus aureus

Indexed keywords

4 (5 ANTHRACEN 9 YL 3 TRIFLUOROMETHYL PYRAZOL 1 YL)BENZAMIDE; AMOXICILLIN; AMPICILLIN; ANTIINFECTIVE AGENT; CELECOXIB; CHLORAMPHENICOL; N [4 (5 ANTHRACEN 2 YL 3 TRIFLUOROMETHYL PYRAZOL 1 YL)PHENYL]AMINOSULFONAMIDE; N [4 (5 ANTHRACEN 9 YL 3 TRIFLUOROMETHYL PYRAZOL 1 YL) PHENYL]AMINOSULFONAMIDE; N [4 (5 BIPHENYL 4 YL 3 TRIFLUOROMETHYL PYRAZOL 1 YL) PHENYL]AMINOSULFONAMIDE; N [4 (5 NAPHTHALEN 2 YL 3 TRIFLUOROMETHYL PYRAZOL 1 YL)PHENYL]AMINOSULFONAMIDE; N [4 (5 PARA TOLYL 3 TRIFLUOROMETHYL PYRAZOL 1 YL) PHENYL]AMINOSULFONAMIDE; N [4 (5 PHENANTHREN 2 YL 3 TRIFLUOROMETHYL PYRAZOL 1 YL)PHENYL] AMINOSULFONAMIDE; N [4 [5 (4' BROMOBIPHENYL 4 YL) 3 TRIFLUOROMETHYL PYRAZOL 1 YL]PHENYL]AMINOSULFONAMIDE; N [4 [5 (4' METHYLBIPHENYL 4 YL) 3 TRIFLUOROMETHYL PYRAZOL 1 YL]PHENYL]AMINOSULFONAMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; CANCER CELL; CHEMICAL MODIFICATION; DRUG EFFICACY; DRUG POTENCY; DRUG RESEARCH; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; MOLECULAR LIBRARY; MOUSE; NONHUMAN; SINGLE DRUG DOSE; SPECIES DIFFERENTIATION; STAPHYLOCOCCUS AUREUS;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HT29 CELLS; HUMANS; INJECTIONS, INTRAPERITONEAL; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICE; MICE, INBRED C57BL; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MUS; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 84863985411     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2012.06.018     Document Type: Article

References (29)

1. D.J. Diekema, M.A. Pfaller, F.J. Schmitz, J. Smayevsky, J. Bell, R.N. Jones, and M. Beach Clin. Infect. Dis. 32 2001 S114
2. K. Plata, A.E. Rosato, and G. Wegrzyn Acta Biochim. Pol. 56 2009 597
3. S.J. Peacock, I. de Silva, and F.D. Lowy Trends Microbiol. 9 2001 605
4. G.C. Schito Clin. Microbiol. Infect. 12 2006 3
5. W.M. Kirby Science 99 1944 452
6. K.R. Eriksen Ugeskr. Laeger. 123 1961 384
7. S. Schaefler, D. Jones, W. Perry, L. Ruvinskaya, T. Baradet, E. Mayr, and M.E. Wilson J. Clin. Microbiol. 13 1981 754
8. H.C. Chiu, S. Soni, S.K. Kulp, H. Curry, D. Wang, J.S. Gunn, L.S. Schlesinger, and C.S. Chen J. Biomed. Sci. 16 2009 110
9. H.C. Chiu, S.K. Kulp, S. Soni, D. Wang, J.S. Gunn, L.S. Schlesinger, and C.S. Chen Antimicrob. Agents Chemother. 53 2009 5236
10. H.C. Chiu, J. Yang, S. Soni, S.K. Kulp, J.S. Gunn, L.S. Schlesinger, and C.S. Chen Antimicrob. Agents Chemother. 53 2009 2998
11. A.M. Kalle, and A. Rizvi Antimicrob. Agents Chemother. 55 2011 439
12. S. Sabatini, F. Gosetto, S. Serritella, G. Manfroni, O. Tabarrini, N. Iraci, J.P. Brincat, E. Carosati, M. Villarini, G.W. Kaatz, and V. Cecchetti J. Med. Chem. 55 2012 3568
13. S.K. Kulp, Y.T. Yang, C.C. Hung, K.F. Chen, J.P. Lai, P.H. Tseng, J.W. Fowble, P.J. Ward, and C.S. Chen Cancer Res. 64 2004 1444
14. H.P. Lin, S.K. Kulp, P.H. Tseng, Y.T. Yang, C.C. Yang, and C.S. Chen Mol. Cancer Ther. 3 2004 1671
15. A.J. Johnson, A.L. Hsu, H.P. Lin, X. Song, and C.S. Chen Biochem. J. 366 2002 831
16. J. Zhu, X. Song, H.P. Lin, D.C. Young, S. Yan, V.E. Marquez, and C.S. Chen J. Natl. Cancer Inst. 94 2002 1745
17. R.M. Donlan Emerg. Infect. Dis. 7 2001 277
18. A.L. Hsu, T.T. Ching, D.S. Wang, X. Song, V.M. Rangnekar, and C.S. Chen J. Biol. Chem. 275 2000 11397
19. C. Waskewich, R.D. Blumenthal, H. Li, R. Stein, D.M. Goldenberg, and J. Burton Cancer Res. 62 2002 2029
20. X. Song, H.P. Lin, A.J. Johnson, P.H. Tseng, Y.T. Yang, S.K. Kulp, and C.S. Chen J. Natl. Cancer Inst. 94 2002 585
21. S. Boyle-Vavra, B. Ereshefsky, C.C. Wang, and R.S. Daum J. Clin. Microbiol. 43 2005 4719
22. W.J. Munckhof, S.L. Kleinschmidt, and J.D. Turnidge Int. J. Antimicrob. Agents 24 2004 605
23. G.A. Pankey, and L.D. Sabath Clin. Infect. Dis. 38 2004 864
24. R.H. Deurenberg, and E.E. Stobberingh Infect. Genet. Evol. 8 2008 747
25. L.M. Weigel, D.B. Clewell, S.R. Gill, N.C. Clark, L.K. McDougal, S.E. Flannagan, J.F. Kolonay, J. Shetty, G.E. Killgore, and F.C. Tenover Science 302 2003 1569
26. L. Cui, H. Murakami, K. Kuwahara-Arai, H. Hanaki, and K. Hiramatsu Antimicrob. Agents Chemother. 44 2000 2276
27. S.F. Altschul, T.L. Madden, A.A. Schaffer, J. Zhang, Z. Zhang, W. Miller, and D.J. Lipman Nucleic Acids Res. 25 1997 3389
28. J. Zhu, J.W. Huang, P.H. Tseng, Y.T. Yang, J. Fowble, C.W. Shiau, Y.J. Shaw, S.K. Kulp, and C.S. Chen Cancer Res. 64 2004 4309
29. Wikler, M. A. Performance Standards for Antimicrobial Susceptibility Testing; Eighteenth Informational Supplement Clinical and Laboratory Standards Institute, 2008.