Confirmation of a proarrhythmic risk underlying the clinical use of common Chinese herbal intravenous injections

Journal of Ethnopharmacology

Volumn 142, Issue 3, 2012, Pages 829-835

  Chen, Long ^a,b   Titch, Tom ^c   Luo, Zhuoka ^a   Xu, Yi ^a   Li, Xuehua ^a   Huang, Feifei ^a   Liu, Lei ^a   Xiao, Wei ^d   Wu, Hao ^a   Wang, Zhongyue ^b  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b Institute of Chinese Medicine of Taizhou China Medical City   (China)

^c ELI LILLY AND COMPANY   (United States)

^d State Key Laboratory of Pharmaceutical Process New teach for Chinese Medicine   (China)

Author keywords

Arrhythmia; Chinese herbal intravenous injection; Electrophysiology; Ion channels

Indexed keywords

CALCIUM CHANNEL L TYPE; CHINESE DRUG; POTASSIUM CHANNEL HERG; QINGKAILING; SHUANGHUAN GLIAN; SODIUM CHANNEL NAV1.5; UNCLASSIFIED DRUG; YINZHIHUANG;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHINESE HERB; CONCENTRATION RESPONSE; CONTROLLED STUDY; ELECTROCARDIOGRAPHY; HEART MUSCLE CELL; HEART PAPILLARY MUSCLE; HEART PROARRHYTHMIA; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PATCH CLAMP;

ACTION POTENTIALS; ANIMALS; ARRHYTHMIAS, CARDIAC; DRUGS, CHINESE HERBAL; ETHER-A-GO-GO POTASSIUM CHANNELS; GUINEA PIGS; HEART VENTRICLES; HEK293 CELLS; HUMANS; INJECTIONS, INTRAVENOUS; MYOCYTES, CARDIAC; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; PAPILLARY MUSCLES; PHYTOTHERAPY; RISK;

CAVIA;

EID: 84863984507     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.06.008     Document Type: Article

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