Mechanism of Pdia3-dependent 1α,25-dihydroxy vitamin D3 signaling in musculoskeletal cells

Steroids

Volumn 77, Issue 10, 2012, Pages 892-896

  Boyan, Barbara D ^a   Chen, Jiaxuan ^a   Schwartz, Zvi ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

1,25(OH)2D3; Caveolae; Chondrocytes; Osteoblasts; Pdia3; Protein kinase C

Indexed keywords

CALCITRIOL; GUANINE NUCLEOTIDE BINDING PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOLIPASE A2; PHOSPHOLIPASE C; PROTEIN DISULFIDE ISOMERASE; PROTEIN DISULFIDE ISOMERASE FAMILY A MEMBER 3; PROTEIN KINASE C; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR;

BONE DEFECT; CARTILAGE CELL; CAVEOLA; CELL CULTURE; CELL DIFFERENTIATION; CELL ISOLATION; CELL MATURATION; CELL MEMBRANE; CELL STRAIN 3T3; CELL VACUOLE; CELLULAR DISTRIBUTION; CHONDROPATHY; CONFERENCE PAPER; DNA MODIFICATION; DOWNSTREAM PROCESSING; EMBRYOID BODY; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; GENE INACTIVATION; GENE OVEREXPRESSION; GENE SILENCING; GROWTH PLATE; HETEROZYGOTE; HUMAN; IMMUNOPRECIPITATION; INTESTINE EPITHELIUM CELL; KNOCKOUT MOUSE; MOUSE STRAIN; NONHUMAN; OSTEOBLAST; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION;

ANIMALS; CALCITRIOL; CELLS, CULTURED; HUMANS; MUSCULOSKELETAL SYSTEM; PROTEIN DISULFIDE-ISOMERASES; PROTEIN TRANSPORT; PROTEINS; RECEPTORS, CALCITRIOL; SIGNAL TRANSDUCTION;

MUS;

EID: 84863984417     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2012.04.018     Document Type: Conference Paper

References (45)

1. G.G. Langston, L.D. Swain, Z. Schwartz, F. Del Toro, R. Gomez, and B.D. Boyan Effect of 1,25(OH)2D3 and 24,25(OH)2D3 on calcium ion fluxes in costochondral chondrocyte cultures Calcified Tissue Int 47 1990 230 236 (Pubitemid 20321276)
2. A.W. Norman, W.H. Okamura, M.C. Farach-Carson, K. Allewaert, D. Branisteanu, and I. Nemere Structure-function studies of 1,25-dihydroxyvitamin D3 and the vitamin D endocrine system. 1,25-dihydroxy-pentadeuterio-previtamin D3 (as a 6-s-cis analog) stimulates nongenomic but not genomic biological responses J Biol Chem 268 1993 13811 13819 (Pubitemid 23195490)
3. R. Liu, W. Li, N.J. Karin, J.J. Bergh, K. Adler-Storthz, and M.C. Farach-Carson Ribozyme ablation demonstrates that the cardiac subtype of the voltage-sensitive calcium channel is the molecular transducer of 1, 25-dihydroxyvitamin D(3)-stimulated calcium influx in osteoblastic cells J Biol Chem 275 2000 8711 8718 (Pubitemid 30180223)
4. B.D. Boyan, V.L. Sylvia, D.D. Dean, H. Pedrozo, F. Del Toro, and I. Nemere 1,25-(OH)2D3 modulates growth plate chondrocytes via membrane receptor-mediated protein kinase C by a mechanism that involves changes in phospholipid metabolism and the action of arachidonic acid and PGE2 Steroids 64 1999 129 136 (Pubitemid 29168596)
5. Z. Schwartz, H. Ehland, V.L. Sylvia, D. Larsson, R.R. Hardin, and V. Bingham 1alpha,25-dihydroxyvitamin D(3) and 24R,25-dihydroxyvitamin D(3) modulate growth plate chondrocyte physiology via protein kinase C-dependent phosphorylation of extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase Endocrinology 143 2002 2775 2786 (Pubitemid 34701342)
6. A.M. Vertino, C.M. Bula, J.R. Chen, M. Almeida, L. Han, and T. Bellido Nongenotropic, anti-apoptotic signaling of 1alpha,25(OH)2-vitamin D3 and analogs through the ligand binding domain of the vitamin D receptor in osteoblasts and osteocytes. Mediation by Src, phosphatidylinositol 3-, and JNK kinases J Biol Chem 280 2005 14130 14137 (Pubitemid 40517315)
7. X. Zhang, and L.P. Zanello Vitamin D receptor-dependent 1 alpha,25(OH)2 vitamin D3-induced anti-apoptotic PI3K/AKT signaling in osteoblasts J Bone Miner Res 23 2008 1238 1248 (Pubitemid 352040178)
8. I. Nemere, M.C. Farach-Carson, B. Rohe, T.M. Sterling, A.W. Norman, and B.D. Boyan Ribozyme knockdown functionally links a 1,25(OH)2D3 membrane binding protein (1,25D3-MARRS) and phosphate uptake in intestinal cells P Natl Acad Sci USA 101 2004 7392 7397 (Pubitemid 38638043)
9. I. Nemere, M.C. Dormanen, M.W. Hammond, W.H. Okamura, and A.W. Norman Identification of a specific binding protein for 1 alpha,25-dihydroxyvitamin D3 in basal-lateral membranes of chick intestinal epithelium and relationship to transcaltachia J Biol Chem 269 1994 23750 23756 (Pubitemid 24293584)
10. I. Nemere, Z. Schwartz, H. Pedrozo, V.L. Sylvia, D.D. Dean, and B.D. Boyan Identification of a membrane receptor for 1,25-dihydroxyvitamin D3 which mediates rapid activation of protein kinase C J Bone Miner Res 13 1998 1353 1359 (Pubitemid 28418900)
11. B.D. Boyan, L.F. Bonewald, V.L. Sylvia, I. Nemere, D. Larsson, and A.W. Norman Evidence for distinct membrane receptors for 1 alpha,25-(OH)(2)D(3) and 24R,25-(OH)(2)D(3) in osteoblasts Steroids 67 2002 235 246 (Pubitemid 34150142)
12. Z. Schwartz, V.L. Sylvia, D. Larsson, I. Nemere, D. Casasola, and D.D. Dean 1alpha,25(OH)2D3 regulates chondrocyte matrix vesicle protein kinase C (PKC) directly via G-protein-dependent mechanisms and indirectly via incorporation of PKC during matrix vesicle biogenesis J Biol Chem 277 2002 11828 11837 (Pubitemid 34952738)
13. V.B. Sequeira, M.S. Rybchyn, W. Tongkao-On, C. Gordon-Thomson, P.J. Malloy, and I. Nemere The role of the vitamin D receptor and ERp57 in photoprotection by 1alpha,25-dihydroxyvitamin D3 Mol Endocrinol. 26 2012 574 582
14. B.D. Boyan, V.L. Sylvia, N. McKinney, and Z. Schwartz Membrane actions of vitamin D metabolites 1alpha,25(OH)2D3 and 24R,25(OH)2D3 are retained in growth plate cartilage cells from vitamin D receptor knockout mice J Cell Biochem 90 2003 1207 1223 (Pubitemid 37485056)
15. R.K. Wali, J. Kong, M.D. Sitrin, M. Bissonnette, and Y.C. Li Vitamin D receptor is not required for the rapid actions of 1,25-dihydroxyvitamin D3 to increase intracellular calcium and activate protein kinase C in mouse osteoblasts J Cell Biochem 88 2003 794 801 (Pubitemid 36258829)
16. V.L. Sylvia, Z. Schwartz, E.B. Ellis, S.H. Helm, R. Gomez, and D.D. Dean Nongenomic regulation of protein kinase C isoforms by the vitamin D metabolites 1 alpha,25-(OH)2D3 and 24R,25-(OH)2D3 J Cell Physiol 167 1996 380 393 (Pubitemid 26168214)
17. S. Maeda, D.D. Dean, V.L. Sylvia, B.D. Boyan, and Z. Schwartz Metalloproteinase activity in growth plate chondrocyte cultures is regulated by 1,25-(OH)(2)D(3) and 24,25-(OH)(2)D(3) and mediated through protein kinase C Matrix Biol 20 2001 87 97 (Pubitemid 32396759)
18. J. Chen, R. Olivares-Navarrete, Y. Wang, T.R. Herman, B.D. Boyan, and Z. Schwartz Protein-disulfide isomerase-associated 3 (Pdia3) mediates the membrane response to 1,25-dihydroxyvitamin D3 in osteoblasts J Biol Chem 285 2010 37041 37050
19. J.L. Costa, P.P. Eijk, M.A. van de Wiel, D. ten Berge, F. Schmitt, and C.J. Narvaez Anti-proliferative action of vitamin D in MCF7 is still active after siRNA-VDR knock-down BMC genomics 10 2009 499
20. Y. Wang, J. Chen, C.S. Lee, A. Nizkorodov, K. Riemenschneider, and D. Martin Disruption of Pdia3 gene results in bone abnormality and affects 1alpha,25-dihydroxy-vitamin D3-induced rapid activation of PKC J Steroid Biochem 121 2010 257 260
21. N. Garbi, S. Tanaka, F. Momburg, and G.J. Hammerling Impaired assembly of the major histocompatibility complex class I peptide-loading complex in mice deficient in the oxidoreductase ERp57 Nat Immunol 7 2006 93 102 (Pubitemid 41823873)
22. I. Nemere, N. Garbi, G.J. Hammerling, and R.C. Khanal Intestinal cell calcium uptake and the targeted knockout of the 1,25D3-MARRS (membrane-associated, rapid response steroid-binding) receptor/PDIA3/Erp57 J Biol Chem 285 2010 31859 31866
23. T. Yoshizawa, Y. Handa, Y. Uematsu, S. Takeda, K. Sekine, and Y. Yoshihara Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning Nat Genet 16 1997 391 396 (Pubitemid 27323308)
24. Y.C. Li, A.E. Pirro, M. Amling, G. Delling, R. Baron, and R. Bronson Targeted ablation of the vitamin D receptor: an animal model of vitamin D-dependent rickets type II with alopecia P Natl Acad Sci USA 94 1997 9831 9835
25. L.P. Zanello, and A.W. Norman Rapid modulation of osteoblast ion channel responses by 1alpha,25(OH)2-vitamin D3 requires the presence of a functional vitamin D nuclear receptor P Natl Acad Sci USA 101 2004 1589 1594 (Pubitemid 38234198)
26. Olivares-Navarrete R, Sutha K, Hyzy SL, Hutton DL, Schwartz Z, McDevitt T, et al. Osteogenic differentiation of stem cells alters vitamin D receptor expression. Stem Cells Dev. 2012, in press.
27. J.D. Oliver, F.J. van der Wal, N.J. Bulleid, and S. High Interaction of the thiol-dependent reductase ERp57 with nascent glycoproteins Science 275 1997 86 88 (Pubitemid 27020314)
28. J.G. Elliott, J.D. Oliver, and S. High The thiol-dependent reductase ERp57 interacts specifically with N-glycosylated integral membrane proteins J Biol Chem 272 1997 13849 13855 (Pubitemid 27224825)
29. J.A. Lindquist, O.N. Jensen, M. Mann, and G.J. Hammerling ER-60, a chaperone with thiol-dependent reductase activity involved in MHC class I assembly EMBO J 17 1998 2186 2195 (Pubitemid 28171904)
30. B.J. Grindel, B. Rohe, S.E. Safford, J.J. Bennett, and M.C. Farach-Carson Tumor necrosis factor-alpha treatment of HepG2 cells mobilizes a cytoplasmic pool of ERp57/1,25D-MARRS to the nucleus J Cell Biochem 112 2011 2606 2615
31. S. Coppari, F. Altieri, A. Ferraro, S. Chichiarelli, M. Eufemi, and C. Turano Nuclear localization and DNA interaction of protein disulfide isomerase ERp57 in mammalian cells J Cell Biochem 85 2002 325 333 (Pubitemid 34274900)
32. B.D. Boyan, K.L. Wong, M. Fang, and Z. Schwartz 1alpha,25(OH)2D3 is an autocrine regulator of extracellular matrix turnover and growth factor release via ERp60 activated matrix vesicle metalloproteinases J Steroid Biochem 103 2007 467 472 (Pubitemid 46401283)
33. I. Gay, Z. Schwartz, V.L. Sylvia, and B.D. Boyan Lysophospholipid regulates release and activation of latent TGF-beta1 from chondrocyte extracellular matrix Biochimica et biophysica acta 1684 2004 18 28 (Pubitemid 39144392)
34. B.D. Boyan, K.L. Wong, L. Wang, H. Yao, R.E. Guldberg, and M. Drab Regulation of growth plate chondrocytes by 1,25-dihydroxyvitamin D3 requires caveolae and caveolin-1 J Bone Miner Res 21 2006 1637 1647 (Pubitemid 44484609)
35. B.D. Boyan, L. Wang, K.L. Wong, H. Jo, and Z. Schwartz Plasma membrane requirements for 1alpha,25(OH)2D3 dependent PKC signaling in chondrocytes and osteoblasts Steroids 71 2006 286 290
36. J. Rubin, Z. Schwartz, B.D. Boyan, X. Fan, N. Case, and B. Sen Caveolin-1 knockout mice have increased bone size and stiffness J Bone Miner Res 22 2007 1408 1418 (Pubitemid 351339685)
37. J.A. Huhtakangas, C.J. Olivera, J.E. Bishop, L.P. Zanello, and A.W. Norman The vitamin D receptor is present in caveolae-enriched plasma membranes and binds 1 alpha,25(OH)2-vitamin D3 in vivo and in vitro Mol Endocrinol 18 2004 2660 2671 (Pubitemid 39482056)
38. Doroudi M, Schwartz Z, Boyan BD. Phospholipase A(2) activating protein is required for 1alpha,25-dihydroxyvitamin D(3) dependent rapid activation of protein kinase C via Pdia3. J Steroid Biochem Mol Biol. 2012, in press.
39. Z. Schwartz, V.L. Sylvia, Y. Liu, D.D. Dean, and B.D. Boyan Treatment of resting zone chondrocytes with bone morphogenetic protein-2 induces maturation into a phenotype characteristic of growth zone chondrocytes by downregulating responsiveness to 24,25(OH)2D3 and upregulating responsiveness to 1,25-(OH)2D3 Endocrine 9 1998 273 280 (Pubitemid 29091515)
40. Z. Schwartz, R.M. Gilley, V.L. Sylvia, D.D. Dean, and B.D. Boyan Prostaglandins mediate the effects of 1,25-(OH)2D3 and 24,25-(OH)2D3 on growth plate chondrocytes in a metabolite-specific and cell maturation-dependent manner Bone 24 1999 475 484 (Pubitemid 29234136)
41. Z. Schwartz, D. Shaked, R.R. Hardin, S. Gruwell, D.D. Dean, and V.L. Sylvia 1alpha,25(OH)2D3 causes a rapid increase in phosphatidylinositol-specific PLC-beta activity via phospholipase A2-dependent production of lysophospholipid Steroids 68 2003 423 437 (Pubitemid 36683174)
42. Z. Schwartz, E.J. Graham, L. Wang, S. Lossdorfer, I. Gay, and T.L. Johnson-Pais Phospholipase A2 activating protein (PLAA) is required for 1alpha,25(OH)2D3 signaling in growth plate chondrocytes J Cell Physiol 203 2005 54 70 (Pubitemid 40328172)
43. D.D. Dean, Z.V. Schwartz, O.E. Muniz, R. Gomez, L.D. Swain, and D.S. Howell Matrix vesicles contain metalloproteinases that degrade proteoglycans Bone Miner 17 1992 172 176
44. D.D. Dean, Z. Schwartz, L. Bonewald, O.E. Muniz, S. Morales, and R. Gomez Matrix vesicles produced by osteoblast-like cells in culture become significantly enriched in proteoglycan-degrading metalloproteinases after addition of beta-glycerophosphate and ascorbic acid Calcified Tissue Int 54 1994 399 408 (Pubitemid 24138759)
45. E.G. Seo, Z. Schwartz, D.D. Dean, A.W. Norman, and B.D. Boyan Preferential accumulation in vivo of 24R,25-dihydroxyvitamin D(3) in growth plate cartilage of rats Endocrine 5 1996 147 155 (Pubitemid 26426710)