Use of recombinant bone morphogenetic protein 2 in free flap reconstruction for osteonecrosis of the mandible

Journal of Oral and Maxillofacial Surgery

Volumn 70, Issue 8, 2012, Pages 1991-1996

  Sweeny, Larissa ^a   Lancaster, William P ^b   Dean, Nichole R ^c   Magnuson, J Scott ^a   Carroll, William R ^a   Louis, Patrick J ^c   Rosenthal, Eben L ^a  

^a University of Alabama at Birmingham   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; INFUSE BONE GRAFT; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; UNCLASSIFIED DRUG;

ADULT; ANTIBIOTIC THERAPY; ARTICLE; BONE DEFECT; BONE INFECTION; BONE MALUNION; BONE NECROSIS; CANCER RADIOTHERAPY; CANCER RECURRENCE; CLINICAL ARTICLE; CONTROLLED STUDY; DEVICE REMOVAL; DRUG SAFETY; FEMALE; FREE TISSUE GRAFT; HEAD AND NECK CANCER; HEALING IMPAIRMENT; HUMAN; HYPERBARIC OXYGEN; JAW OSTEONECROSIS; MALE; PLASTIC SURGERY; REOPERATION; RETROSPECTIVE STUDY; TREATMENT OUTCOME; WOUND CARE;

BONE MORPHOGENETIC PROTEIN 2; BONE PLATES; BONE TRANSPLANTATION; CARCINOMA, SQUAMOUS CELL; COHORT STUDIES; DEVICE REMOVAL; FEMALE; FOLLOW-UP STUDIES; FREE TISSUE FLAPS; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MANDIBLE; MANDIBULAR DISEASES; MIDDLE AGED; OSTEORADIONECROSIS; OSTEOTOMY; POSTOPERATIVE COMPLICATIONS; RECOMBINANT PROTEINS; RECONSTRUCTIVE SURGICAL PROCEDURES; RETROSPECTIVE STUDIES; SKIN TRANSPLANTATION; SURGICAL WOUND DEHISCENCE; SURGICAL WOUND INFECTION; TRANSFORMING GROWTH FACTOR BETA; TREATMENT OUTCOME; WOUND HEALING;

EID: 84863982370     PISSN: 02782391     EISSN: 15315053     Source Type: Journal    
DOI: 10.1016/j.joms.2011.08.037     Document Type: Article

References (37)

1. R.E. Marx Osteoradionecrosis: A new concept of its pathophysiology J Oral Maxillofac Surg 41 1983 283
2. R.E. Marx, R.P. Johnson Studies in the radiobiology of osteoradionecrosis and their clinical significance Oral Surg Oral Med Oral Pathol 64 1987 379
3. D.E. Peterson, W. Doerr, A. Hovan Osteoradionecrosis in cancer patients: The evidence base for treatment-dependent frequency, current management strategies, and future studies Support Care Cancer 18 2010 1089
4. S.E. Hunter, R.L. Scher Clinical implications of radionecrosis to the head and neck surgeon Curr Opin Otolaryngol Head Neck Surg 11 2003 103
5. Y. Monnier, M. Broome, M. Betz Mandibular osteoradionecrosis in squamous cell carcinoma of the oral cavity and oropharynx: Incidence and risk factors Otolaryngol Head Neck Surg 144 2011 726
6. R.E. Marx A new concept in the treatment of osteoradionecrosis J Oral Maxillofac Surg 41 1983 351
7. R.E. Marx, R.P. Johnson, S.N. Kline Prevention of osteoradionecrosis: A randomized prospective clinical trial of hyperbaric oxygen versus penicillin J Am Dent Assoc 111 1985 49
8. D. Annane, J. Depondt, P. Aubert Hyperbaric oxygen therapy for radionecrosis of the jaw: A randomized, placebo-controlled, double-blind trial from the ORN96 study group J Clin Oncol 22 2004 4893
9. D.W. Klotch, J. Gump, L. Kuhn Reconstruction of mandibular defects in irradiated patients Am J Surg 160 1990 396
10. E. Ang, C. Black, J. Irish Reconstructive options in the treatment of osteoradionecrosis of the craniomaxillofacial skeleton Br J Plast Surg 56 2003 92
11. D.W. Chang, H.K. Oh, G.L. Robb Management of advanced mandibular osteoradionecrosis with free flap reconstruction Head Neck 23 2001 830
12. L. Wang, Y.X. Su, G.Q. Liao Quality of life in osteoradionecrosis patients after mandible primary reconstruction with free fibula flap Oral Surg Oral Med Oral Pathol Oral Radiol Endod 108 2009 162
13. O.N. Militsakh, D.I. Wallace, J.D. Kriet The role of the osteocutaneous radial forearm free flap in the treatment of mandibular osteoradionecrosis Otolaryngol Head Neck Surg 133 2005 80
14. M.M. Curi, M. Oliveira dos Santos, O. Feher Management of extensive osteoradionecrosis of the mandible with radical resection and immediate microvascular reconstruction J Oral Maxillofac Surg 65 2007 434
15. H.D. Sandel, S.P. Davison Microsurgical reconstruction for radiation necrosis: An evolving disease J Reconstr Microsurg 23 2007 225
16. D.L. Hirsch, R.B. Bell, E.J. Dierks Analysis of microvascular free flaps for reconstruction of advanced mandibular osteoradionecrosis: A retrospective cohort study J Oral Maxillofac Surg 66 2008 2545
17. Y. Okubo, K. Bessho, K. Fujimura Osteogenesis by recombinant human bone morphogenetic protein-2 at skeletal sites Clin Orthop Relat Res 2000 295
18. Y. Okubo, K. Bessho, K. Fujimura Osteoinduction by recombinant human bone morphogenetic protein-2 at intramuscular, intermuscular, subcutaneous and intrafatty sites Int J Oral Maxillofac Surg 29 2000 62
19. J.K. Burkus, M.F. Gornet, T.C. Schuler Six-year outcomes of anterior lumbar interbody arthrodesis with use of interbody fusion cages and recombinant human bone morphogenetic protein-2 J Bone Joint Surg Am 91 2009 1181
20. M.A. Fallucco, M.H. Carstens Primary reconstruction of alveolar clefts using recombinant human bone morphogenic protein-2: Clinical and radiographic outcomes J Craniofac Surg 20 suppl 2 2009 1759
21. B.P. Dickinson, R.K. Ashley, K.L. Wasson Reduced morbidity and improved healing with bone morphogenic protein-2 in older patients with alveolar cleft defects Plast Reconstr Surg 121 2008 209
22. R.G. Triplett, M. Nevins, R.E. Marx Pivotal, randomized, parallel evaluation of recombinant human bone morphogenetic protein-2/absorbable collagen sponge and autogenous bone graft for maxillary sinus floor augmentation J Oral Maxillofac Surg 67 2009 1947
23. A.S. Herford rhBMP-2 as an option for reconstructing mandibular continuity defects J Oral Maxillofac Surg 67 2009 2679
24. S. Govender, C. Csimma, H.K. Genant Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: A prospective, controlled, randomized study of four hundred and fifty patients J Bone Joint Surg Am 84 2002 2123
25. B.K. Howard, K.R. Brown, J.L. Leach Osteoinduction using bone morphogenic protein in irradiated tissue Arch Otolaryngol Head Neck Surg 124 1998 985
26. K.K. Würzler, T.L. DeWeese, W. Sebald Radiation-induced impairment of bone healing can be overcome by recombinant human bone morphogenetic protein-2 J Craniofac Surg 9 1998 131
27. O.N. Militsakh, A. Werle, N. Mohyuddin Comparison of radial forearm with fibula and scapula osteocutaneous free flaps for oromandibular reconstruction Arch Otolaryngol Head Neck Surg 131 2005 571
28. F.W. Virgin, T.A. Iseli, C.E. Iseli Functional outcomes of fibula and osteocutaneous forearm free flap reconstruction for segmental mandibular defects Laryngoscope 120 suppl 4 2010 S190
29. J.D. Smucker, J.M. Rhee, K. Singh Increased swelling complications associated with off-label usage of rhBMP-2 in the anterior cervical spine Spine (Phila Pa 1976) 31 2006 2813
30. M.P. Garrett, U.K. Kakarla, R.W. Porter Formation of painful seroma and edema after the use of recombinant human bone morphogenetic protein-2 in posterolateral lumbar spine fusions Neurosurgery 66 2010 1044
31. L.M. Tumialán, J. Pan, G.E. Rodts The safety and efficacy of anterior cervical discectomy and fusion with polyetheretherketone spacer and recombinant human bone morphogenetic protein-2: A review of 200 patients J Neurosurg Spine 8 2008 529
32. C. d'Hauthuille, S. Testelin, C. Moure Mandibular osteoradionecrosis Part II: Efficiency of revascularization surgery Rev Stomatol Chir Maxillofac 109 2008 296 in French
33. S.B. Cannady, N. Dean, A. Kroeker Free flap reconstruction for osteoradionecrosis of the jaws - Outcomes and predictive factors for success Head Neck 33 2011 424
34. Q. Gao, W. Tong, J.S. Luria Effects of bone morphogenetic protein-2 on proliferation and angiogenesis in oral squamous cell carcinoma Int J Oral Maxillofac Surg 39 2010 266
35. D. Mines, Y. Gu, T.D. Kou Recombinant human bone morphogenetic protein-2 and pancreatic cancer: A retrospective cohort study Pharmacoepidemiol Drug Saf 20 2011 111
36. V. Alt, A. Chhabra, J. Franke An economic analysis of using rhBMP-2 for lumbar fusion in Germany, France and UK from a societal perspective Eur Spine J 18 2009 800
37. V. Alt, S.T. Donell, A. Chhabra A health economic analysis of the use of rhBMP-2 in Gustilo-Anderson grade III open tibial fractures for the UK, Germany, and France Injury 40 2009 1269