Intra-abdominal clear-cell sarcoma: A report of 3 cases, including 1 case with unusual morphological features, and review of the literature

International Journal of Surgical Pathology

Volumn 20, Issue 4, 2012, Pages 378-385

  Shenjere, Patrick ^a   Salman, Walid D ^b   Singh, Mayuri ^b   Mangham, David Chas ^c,d   Williams, Ann ^d   Eyden, Brian Philip ^a   Howard, Nicholas ^b   Knight, Ben ^b   Banerjee, Saumitra S ^a  

^a CHRISTIE HOSPITAL   (United Kingdom)

^b EAST LANCASHIRE HOSPITALS NHS TRUST   (United Kingdom)

^c ROBERT JONES AND AGNES HUNT ORTHOPAEDIC HOSPITAL   (United Kingdom)

^d ROYAL ORTHOPAEDIC HOSPITAL   (United Kingdom)

Author keywords

clear cell sarcoma; intra abdominal; molecular studies; unusual morphology

Indexed keywords

CD57 ANTIGEN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; EPITHELIAL MEMBRANE ANTIGEN; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; PROTEIN BCL 2; PROTEIN S 100; VIMENTIN;

ABDOMINAL DISTENSION; ABDOMINAL PAIN; ADULT; AGED; ANTIGEN EXPRESSION; CASE REPORT; CELL DEATH; CELL JUNCTION; CELL STRUCTURE; CLEAR CELL SARCOMA; COMPUTED TOMOGRAPHIC COLONOGRAPHY; CYTOPLASM; DNA SEQUENCE; FEMALE; GENE REARRANGEMENT; GENE TRANSLOCATION; HUMAN; IMMUNOHISTOCHEMISTRY; LYMPH NODE HYPERPLASIA; MALE; MITOSIS; PERITONEUM CANCER; PERITONEUM CLEAR CELL SARCOMA; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; SMALL INTESTINE CANCER; SMALL INTESTINE CLEAR CELL SARCOMA;

ABDOMINAL NEOPLASMS; ADULT; AGED; DNA, NEOPLASM; FEMALE; GENE FUSION; GENE REARRANGEMENT; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INTESTINE, SMALL; LYMPH NODES; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; MUCIN-1; PATHOLOGY, MOLECULAR; PERITONEUM; SARCOMA, CLEAR CELL; SOFT TISSUE NEOPLASMS; TRANSLOCATION, GENETIC; TUMOR MARKERS, BIOLOGICAL;

EID: 84863962111     PISSN: 10668969     EISSN: 19402465     Source Type: Journal    
DOI: 10.1177/1066896911425485     Document Type: Review

References (39)

1. Chung EB, Enzinger FM. Malignant melanoma of soft parts: a reassessment of clear cell sarcoma. Am J Surg Pathol. 1983 ; 7: 405-413 (Pubitemid 13006786)
2. Enzinger FM. Clear-cell sarcoma of tendons and aponeuroses: an analysis of 21 cases. Cancer. 1965 ; 18: 1163-1174
3. Achten R, Debiec-Rychter M, De Wever I, Sciot R. An unusual case of clear cell sarcoma arising in the jejunum highlights the diagnostic value of molecular genetic techniques in establishing a correct diagnosis. Histopathology. 2005 ; 46: 472-474 (Pubitemid 40516768)
4. Antonescu CR, Nafa K, Segal NH, Dal Cin P, Ladanyi M. EWS-CREB1: a recurrent variant fusion in clear cell sarcoma- association with gastrointestinal location and absence of melanocytic differentiation. Clin Cancer Res. 2006 ; 12: 5356-5362 (Pubitemid 44497248)
5. Bury T, Hermans G, Alexis-Agnant R, Chevalier P, Limet R, Bartsch P. Clear cell sarcoma: an extremely rare cause of pleural disease. Eur Respir J. 1997 ; 10: 2653-2656 (Pubitemid 28048647)
6. Covinsky M, Gong S, Rajaram V, Perry A, Pfeifer J. EWS-ATF1 fusion transcripts in gastrointestinal tumors previously diagnosed as malignant melanoma. Hum Pathol. 2005 ; 36: 74-81 (Pubitemid 40215636)
7. Donner LR, Trompler RA, Dobin S. Clear cell sarcoma of the ileum: the crucial role of cytogenetics for the diagnosis. Am J Surg Pathol. 1998 ; 22: 121-124 (Pubitemid 28016761)
8. Ekfors TO, Kujari H, Isomäki M. Clear cell sarcoma of tendons and aponeuroses (malignant melanoma of soft parts) in the duodenum: the first visceral case. Histopathology. 1993 ; 22: 255-259 (Pubitemid 23105134)
9. Friedrichs N, Testi MA, Moiraghi L, et al. Clear cell sarcoma-like tumor with osteoclast-like giant cells in the small bowel: further evidence for a new tumor entity. Int J Surg Pathol. 2005 ; 13: 313-318 (Pubitemid 41688592)
10. Fukuda T, Kakihara T, Baba K, Yamaki T, Yamaguchi T, Suzuki T. Clear cell sarcoma arising in the transverse colon. Pathol Int. 2000 ; 50: 412-416 (Pubitemid 30451485)
11. Hersekli MA, Ozkoc G, Bircan S, et al. Primary clear cell sarcoma of rib. Skeletal Radiol. 2005 ; 34: 167-170 (Pubitemid 40305458)
12. Huang W, Zhang X, Li D, et al. Osteoclast-rich tumor of the gastrointestinal tract with features resembling those of clear cell sarcoma of soft parts. Virchows Arch. 2006 ; 448: 200-203 (Pubitemid 43237886)
13. Pauwels P, Debiec-Rychter M, Sciot R, et al. Clear cell sarcoma of the stomach. Histopathology. 2002 ; 41: 526-530 (Pubitemid 36693598)
14. Rubin BP, Fletcher JA, Renshaw AA. Clear cell sarcoma of soft parts: report of a case primary in the kidney with cytogenetic confirmation. Am J Surg Pathol. 1999 ; 23: 589-594 (Pubitemid 29214963)
15. Saw D, Tse CH, Chan J, Watt CY, Ng CS, Poon YF. Clear cell sarcoma of the penis. Hum Pathol. 1986 ; 17: 423-425 (Pubitemid 16018581)
16. Taminelli L, Zaman K, Gengler C, et al. Primary clear cell sarcoma of the ileum: an uncommon and misleading site. Virchows Arch. 2005 ; 447: 772-777 (Pubitemid 41571195)
17. Venkataraman G, Quinn AM, Williams J, Hammadeh R. Clear cell sarcoma of the small bowel: a potential pitfall. Case report. APMIS. 2005 ; 113: 716-719 (Pubitemid 41771818)
18. Zambrano E, Reyes-Mugica M, Franchi A, Rosai J. An osteoclast-rich tumor of the gastrointestinal tract with features resembling clear cell sarcoma of soft parts: reports of 6 cases of a GIST simulator. Int J Surg Pathol. 2003 ; 11: 75-81 (Pubitemid 36569928)
19. Kindblom LG, Lodding P, Angervall L. Clear-cell sarcoma of tendons and aponeuroses: an immunohistochemical and electron microscopic analysis indicating neural crest origin. Virchows Arch A Pathol Anat Histopathol. 1983 ; 401: 109-128 (Pubitemid 13035180)
20. Meis-Kindblom JM. Clear cell sarcoma of tendons and aponeuroses: a historical perspective and tribute to the man behind the entity. Adv Anat Pathol. 2006 ; 13: 286-292 (Pubitemid 44673444)
21. Graadt van Roggen JF, Mooi WJ, Hogendoorn PC. Clear cell sarcoma of tendons and aponeuroses (malignant melanoma of soft parts) and cutaneous melanoma: exploring the histogenetic relationship between these two clinicopathological entities. J Pathol. 1998 ; 186: 3-7 (Pubitemid 28407481)
22. Dim DC, Cooley LD, Miranda RN. Clear cell sarcoma of tendons and aponeuroses: a review. Arch Pathol Lab Med. 2007 ; 131: 152-156 (Pubitemid 46174153)
23. Hisaoka M, Ishida T, Kuo TT, et al. Clear cell sarcoma of soft tissue: a clinicopathologic, immunohistochemical, and molecular analysis of 33 cases. Am J Surg Pathol. 2008 ; 32: 452-460 (Pubitemid 351398938)
24. Panagopoulos I, Mertens F, Isaksson M, Mandahl N. Absence of mutations of the BRAF gene in malignant melanoma of soft parts (clear cell sarcoma of tendons and aponeuroses). Cancer Genet Cytogenet. 2005 ; 156: 74-76 (Pubitemid 39601063)
25. Hallor KH, Micci F, Meis-Kindblom JM, et al. Fusion genes in angiomatoid fibrous histiocytoma. Cancer Lett. 2007 ; 251: 158-163 (Pubitemid 46589772)
26. Wang WL, Mayordomo E, Zhang W, et al. Detection and characterization of EWSR1/ATF1 and EWSR1/CREB1 chimeric transcripts in clear cell sarcoma (melanoma of soft parts). Mod Pathol. 2009 ; 22: 1201-1209
27. Pacheco M, Horsman DE, Hayes MM, Clarkson PW, Huwait H, Nielsen TO. Small blue round cell tumor of the interosseous membrane bearing a t(2;22)(q34;q12)/EWS-CREB1 translocation: a case report. Mol Cytogenet. 2010 ; 3: 12
28. Lyle PL, Amato CM, Fitzpatrick JE, Robinson WA. Gastrointestinal melanoma or clear cell sarcoma? Molecular evaluation of 7 cases previously diagnosed as malignant melanoma. Am J Surg Pathol. 2008 ; 32: 858-866
29. Kosemehmetoglu K, Folpe AL. Clear cell sarcoma of tendons and aponeuroses, and osteoclast-rich tumour of the gastrointestinal tract with features resembling clear cell sarcoma of soft parts: a review and update. J Clin Pathol. 2010 ; 63: 416-423
30. Granville L, Hicks J, Popek E, Dishop M, Tatevian N, Lopez-Terrada D. Visceral clear cell sarcoma of soft tissue with confirmation by EWS-ATF1 fusion detection. Ultrastruct Pathol. 2006 ; 30: 111-118 (Pubitemid 44178578)
31. Terazawa K, Otsuka H, Morita N, Yamashita K, Nishitani H. Clear-cell sarcoma of the small intestine detected by FDG-PET/CT during comprehensive examination of an inflammatory reaction. J Med Invest. 2009 ; 56: 70-75
32. Joo M, Chang SH, Kim H, Gardner JM, Ro JY. Primary gastrointestinal clear cell sarcoma: report of 2 cases, one case associated with IgG4-related sclerosing disease, and review of literature. Ann Diagn Pathol. 2009 ; 13: 30-35
33. Lagmay JP, Ranalli M, Arcila M, Baker P. Clear cell sarcoma of the stomach. Pediatr Blood Cancer. 2009 ; 53: 214-216
34. Abdulkader I, Cameselle-Teijeiro J, de Alava E, Ruiz-Ponte C, Used-Aznar MM, Forteza J. Intestinal clear cell sarcoma with melanocytic differentiation and EWS [corrected] rearrangement: report of a case. Int J Surg Pathol. 2008 ; 16: 189-193 (Pubitemid 351549754)
35. Garcia JJ, Kramer MJ, Mackey ZB, O'Donnell RJ, Horvai AE. Utility of CD117 immunoreactivity in differentiating metastatic melanoma from clear cell sarcoma. Arch Pathol Lab Med. 2006 ; 130: 343-348
36. Washington K, McDonagh D. Secondary tumors of the gastrointestinal tract: surgical pathologic findings and comparison with autopsy survey. Mod Pathol. 1995 ; 8: 427-433
37. Folpe AL, Mentzel T, Lehr HA, Fisher C, Balzer BL, Weiss SW. Perivascular epithelioid cell neoplasms of soft tissue and gynecologic origin: a clinicopathologic study of 26 cases and review of the literature. Am J Surg Pathol. 2005 ; 29: 1558-1575
38. Davis IJ, Kim JJ, Ozsolak F, et al. Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers. Cancer Cell. 2006 ; 9: 473-484 (Pubitemid 43832189)
39. Segal NH, Pavlidis P, Noble WS, et al. Classification of clear-cell sarcoma as a subtype of melanoma by genomic profiling. J Clin Oncol. 2003 ; 21: 1775-1781 (Pubitemid 46638591)